Centre for Microbial Research
The Centre for Microbial Research (CMR) was created as a niche Centre of THSTI to explore the interactions between microorganisms and humans and to better understand the role and effect of microorganisms in human health and disease. In addition, CMR is actively involved in Antimicrobial Resistance research for diagnostic and therapeutic development. The promising part of CMR is the integration of fundamental and clinical sciences for disease understanding, biotherapeutic discovery, and reducing infectious disease burden to a greater extent.
Major programs
- Human Microbiome Research
Objective: Understand the composition, diversity, dynamics, and functions of the microbiome in health and disease. Currently, microbiome research has a major focus on non-alcoholic fatty liver disease, sepsis, cancer, and preterm birth
- Antibiotic Resistance Research
Objective 1: Decoding the whole genome sequences of bacterial pathogens associated with sepsis, urinary tract infections, respiratory infections, and understand the resistance heterogeneity in different pathogens.
Objective 2: Rapid detection of antimicrobial resistance traits in clinical samples adopting molecular approaches.
Objective 3: Developing alternative therapy including antibiotic potentiators discovery, phage therapy, antibiofilm agents for MDR and PDR infections.
Objective 4: Integrative data mining for genome based rapid detection of antibiotic resistance in Gram-negative ESKAPE pathogens.
Objective 5: Development of rapid peptide-based MRM-MS assays for sensitive and specific identification of MDR bacterial pathogens from clinical samples.
- Neonatal Sepsis Research
Objective 1: Study sepsis pathogenesis and discover novel therapeutics and diagnostics.
Objective 2: Discover the potential reservoirs of sepsis-causing bacterial pathogens and their transmission dynamics.
Objective 3: Understand host genetic variations associated with increased susceptibility to neonatal sepsis and death.
Objective 4: Understand the role of the gut microbiome (bacteria, fungi, viruses) in neonatal sepsis.
Name of faculty members and Scientists
DR. BHABATOSH DAS, PROFESSOR
DR. KRISHNAMOHAN ATMAKURI, ASSOCIATE PROFESSOR
DR. DINESH MAHAJAN, ASSOCIATE PROFESSOR
DR. SUSMITA CHAUDHURI, ASSOCIATE PROFESSOR
DR. AMIT KUMAR YADAV, PRINCIPAL SCIENTIST-II
DR. YASHWANT KUMAR, SENIOR RESEARCH SCIENTIST
DR. DAIZEE TALUKDAR, RESEARCH SCIENTIST
DR. DEEPJYOTI PAUL, RESEARCH SCIENTIST
DR. PRABHAKAR BABELE, RESEARCH SCIENTIST
The centre/facility is open to providing services to academia and industry. For any queries, contact the following
Contact Details
Dr. Bhabatosh Das
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bhabatosh@thsti.res.in
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0129- 2876471
