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DR. BHABATOSH DAS, M.Sc., M.Tech., Ph.D.  

Associate Professor
+91-129-2876471 
bhabatosh [at] thsti [dot] res [dot] in
2017: JSPS Fellow, Osaka University, Japan
2008-2011: CNRS Fellow, The Institute of Integrative Biology of the Cell, France
2006-2008: CSIR Research Fellow, Indian Institute of Chemical Biology, India
2003-2006: ICMR Research Fellow, Indian Institute of Chemical Biology, India
2001-2003: M.Tech., Biotech. & Biochem. Eng., IIT-Kharagpur, India
1998-2000: M.Sc., Zoology, Visva-Bharati University, Santiniketan, India


Currently, my lab is working to understand the genomic repertoires of microbial community associated with (a) gastroenteritis (b) antimicrobial resistance and (c) preterm birth.
 

(1) Gastroenteritis: We are working on the gastrointestinal tract microbiome of Indian population and investigating role of gut microbiota in the Health and diseases including (i) chronic and acute diarrhoea (ii) Neonatal sepsis and (iii) Nonalcoholic fatty liver disease (NAFLD).
 

(2) Antimicrobial resistance (AMR): Emergence of antimicrobial resistant bacterial pathogens is a global concern. We are probing whole genome sequences of bacterial pathogens to identify horizontally acquired genetic elements linked with AMR genes and understand the acquisition and dissemination mechanisms of AMR traits. We have also initiated research to resensitise resistant pathogens by (i) inducing bacterial genome instability and (ii) inhibiting microbial functions linked with non-inheritable antimicrobial resistance.

(3) Preterm birth (PTB): We are studying the vaginal microbiome of Indian women and examining (i) role of vaginal microbiota in the birth outcomes (ii) specific microbial genomic signatures positively or negatively associated with PTB. We have isolated different Lactobacillus species from the vaginal milieu of Indian women and decoding their genome sequences and to identify functions associated with birth outcomes.  

2021

64. Pinna N.K., Anjana R. M., Saxena S., Dutta A., Gnanaprakash V., Gnanavadivel R., Sukumaran A., Raghavan S., Subramanian C., Rani S., Radha V., Balasubramanyam M., Pant A., Nielsen T., Jorgensen T., Færch K., Kashani A., Camila M., Silva A., Vestergaard H., Haldor T.H., Hansen T., Arumugam T., Nair G.B., Das B., Pedersen O., Mohan V., Mande S. (2020) Trans-ethnic gut microbial signatures of prediabetic subjects from India and Denmark. Genome Medicine. 13:36  (Corresponding author).

 

63. Will R.C., Ramamurthy T., Sharma N.C., Balaji V., Pragasam A., Vasudevan K., Kumar D., Das D., Heinz E., Melnikov V., Sangal V., Dougan G., Mutreja A. (2020) Spatiotemporal persistence of multiple, diverse clones and toxins of Corynebacterium diphtheriaNature communication. 12:1500.

 

62. Alvarez-Silva C., Kashani A., Hansen T.H., Pinna N.K., Anjana R.M., Dutta A., Saxena S., Stoy J., Kampmann U., Nielsen T., Jorgensen T., Gnanaprakash V., Gnanavadivel R., Sukumaran A., Rani C.S.S., Færch K., Radha V., Balasubramanyam M., Nair G.B., Das B., Vestergaard H., Hansen T., Mande S.S., Mohan V., Arumugam M., Pedersen O. (2020) Transethnic gut microbiota signatures of type 2 diabetes in Denmark and India. Genome Medicine. 13.36.

 

61. Devi T.B., Devadas K., George M., Gandhimathi A., Chouhan D., Retnakumar R.J., Alexander S.M., Vargheses J., Sanjai D., Sivakumar K.C., Das B., Nair G.B., Chattopadhyay S., (2020) Low Bifidobacterium abundance in intestinal microbiome is related to Helicobacter pylori infection and severe gastric diseases. Front. Microbiology. doi: 10.3389/fmicb.2021.631140

2020

60. Pant A., Bag S., Saha B. Verma J., Banerjee S., Kumar P., Kumar B., Kumar Y., Desigamani A., Maiti S., Maiti T., Banerjee S., Koley H., Dutta S., Nair G., Ramamurthy T., Das B. (2020). Molecular Insights into the genome dynamics and interactions between core and acquired genome of Vibrio cholerae. Proc. Natl. Acad. Sci, USA. doi/10.1073/pnas.2006283117

Highlighted: Nature India (Genetically engineered cholera bug may yield vaccines, drugs)
https://www.natureasia.com/en/nindia/article/10.1038/nindia.2020.144

59. Das B., and Bhadra R.K. (2020) (p)ppGpp Metabolism and Antimicrobial Resistance in Bacterial Pathogens. Front. Microbiology. doi: 10.3389/fmicb.2020.563944

58. Rakshit D., Dasgupta S., Das B., Bhadra R.K. (2020) Functional Insights into the Role of gppA in (p)ppGpp Metabolism of Vibrio cholerae. Front. Microbiology. doi: 10.3389/fmicb.2020.564644

57. Kumar A., Das B., Kumar N. (2020) Vibrio Pathogenicity Island-1: The Master Determinant of Cholera Pathogenesis. Front. Cell. Infect. Microbiol. | doi: 10.3389/fcimb.2020.561296

56. Kedia1 S., Ghosh T.S., Jain S., Desigamani A., Kumar A., Gupta V., Bopanna S., Yadav D.P., Goyal S., Makharia G., Travis S., Das B., and Ahuja V (2020) Gut microbiome diversity in acute severe colitis is distinct from mild to moderate ulcerative colitis. J. Gast. Hepat. doi: 10.1111/jgh.15232

55. Mehta O., Ghosh T.S., Kothidar A., Gowtham M.R., Mitra R., Kshetrapal P., Wadhwa N., Ramachandran T., GARBH-Ini study group, G. Balakrish Nair, Bhatnagar S., Das B. (2020) The vaginal microbiome of pregnant Indian women: Insights into the genome of dominants Lactobacillus species. Mic. Ecol. (Human Microbiome). doi:10.1007/s00248-020-01501-0

Highlighted: Nature India (Friendly bugs protect pregnant women)
https://www.natureasia.com/en/nindia/article/10.1038/nindia.2020.85

Highlighted: Research Matters (Vaginal microbiome: New insights into vaginal microbes may help to reduce premature birth)
https://researchmatters.in/news/new-insights-vaginal-microbes-may-help-reduce-premature-birth?fbclid=IwAR1X2OCwCVwg40tRG1WO6auktcpqHSCqq0SHPfI_8h4chhokQfxlgXiYeTw

54. Chaterjee P., Nagi N., Agarwal A., Das B., Banerjee S., Sarkar S., Gupta N., Gangakhedkar R., Bhargava B. (2020). The 2019 novel coronavirus disease (COVID-19) pandemic: A review of the current evidence. Ind. J. Med. Res. DOI:10.4103/ijmr.IJMR_519_20.

2019
53. Das B. (2019). Insights into TLCΦ Lysogeny: A Twist in the mechanism of IMEXs Integration. Proc. Natl. Acad. Sci, USA. 2019 Aug 22. pii: 201912633  doi: 10.1073/pnas.1912633116. (IF=10.4)

52. Verma J., Bag S., Saha B., Kumar P., Ghosh T.S., Dayal M., Dey P., Anbumani D., Kumar D., Rana P., Kumar B., Maiti T., Sharma N.C., Bhadra R.K., Mutreja A., Nair G.B., Ramamurthy T., Das B. (2019) Genomic Plasticity associated with the antimicrobial resistance in Vibrio cholerae. Proc. Natl. Acad. Sci, USA. 116:6226-6231.doi.org/10.1073/pnas.1900141116. (IF=10.4)

Highlighted: Nature India (How cholera bacteria defy antibiotics)
https://www.natureasia.com/en/nindia/article/10.1038/nindia.2019.40

Highlighted: The Hindu (Cholera bacteria have become highly drug-resistant)
https://www.thehindu.com/sci-tech/science/cholera-bacteria-have-become-highly-drug-resistant/article29309292.ece

51. Sharma N.C., Efstratiou A., Guaraldi A.L.M., Mokrousov I., Mutreja A., Das B., Ramamurthy T. (2019). Diptheria. Nature Reviews Disease Primers. 2019 Dec 5;5(1):81 https://doi.org/10.1038/s41572-019-0131-y  (IF=32.3)

50. Bag S., Ghosh T.S., Banerjee S., Mehta O, Verma J., Dayal M., Anbumani D., Kumar P., Saha B., Kedia S., Ahuja V., Ramamurthy T., Das B. (2019). Molecular Insights into Antimicrobial Resistance Traits of Commensal Human Gut Microbiota. Mic. Ecol. (Human Microbiome) 77(2):546-557.

Highlighted: Nature India (Pathogens pick up drug resistance genes from friendly bacteria)
https://www.natureasia.com/en/nindia/article/10.1038/nindia.2018.95

49. Pareek S., Kurakawa T., Das B., Motooka D., Nakaya S., Rongsen-Chandola T., Goyal N., Kayama H., Dodd D., Okumura R., Maeda Y., Fujimoto K., Nii T., Ogawa T., Iida T., Bhandari B., Kida T., Nakamura S., Nair G.B., Takeda K. (2019) A comparative analysis of intestinal microbiota diversity between Japanese and Indian population shows diet dependent interaction of bacteria and fungi. npj/Biofilms and Microbiomes. doi.org/10.1038/s41522-019-0110-9.

48. Das B., Verma J., Kumar P., Ghosh A., Ramamurthy T. (2019). Antibiotic Resistance in Vibrio cholerae: Understanding the Genesis and Mechanisms. Vaccine. pii: S0264-410X(19)30793-5.

47. Basu P., Das B., Bhadra R.K. (2019). Research on Vibrio cholerae in India: Last 10 years upshots. Proc. Ind. Natl.  Sci. Acad. (Accepted)

46. Pant A., Das B., Bhadra RK. (2019) CTX phage of Vibrio cholerae: Genomics and applications. Vaccine. S0264-410X(19)30796-0.



45. Das B. and Chattoraj D.K. (2019). Commentary: Functionality of Two Origins of Replication in Vibrio cholerae Strains with a Single Chromosome. Front. Microbiol. 2019 Jun 19;10:1314. doi:10.3389/fmicb.2019.01314.

44. Ramamurthy T, Mutreja A, Weill FX, Das B, Ghosh A, Nair GB.(2019) Revisiting the Global Epidemiology of Cholera in Conjunction With the Genomics of Vibrio cholerae. Front Public Health. 2019 Jul 23;7:203. doi: 10.3389/fpubh.2019.00203.



43. Das B. and Nair G.B. (2019). Homeostasis and Dysbiosis of the Gut Microbiome in Health and Disease. J. Bioscience. DOI: 10.1007/s12038-019-9926-y.

42. Ramamurthy T., Das B., Mukhopadhyay A., Debes AK., Chakraborty S., Sack D. (2019). Diagnostic techniques for rapid detection of Vibrio cholerae O1/O139. Vaccine. 2019 Aug 16. pii: S0264-410X(19)31020-5.

41. Senapati T., Kothidar A., Banerjee S. Das B. (2019). Insights Into the Gastrointestinal Tract Microbiomes of Indian Population. J. Bioscience. DOI: 10.1007/s12038-019-9927-x



40. Adela R., Reddy PNC, Ghosh TS., Aggarwal S., Yadav A., Das B., Banerjee S (2019). Serum Protein Signature of Coronary Artery Disease in Type-2 Diabetes Mellitus. J. Transl. Medicine. 2019:17 doi.org/10.1186/s12967-018-1755-5

2018


2018

39. Das B. Ghosh TS., Kedia S., Rampal R., Saxena S., Bag S., Ridhima M.,  Dayal M., Mehta O., Surendranath A., Travis SPL., Tripathi P., Nair GB., Ahuja V. (2018). Analysis of the gut microbiome of Rural and Urban Healthy Indians living in Sea level and High Altitude Areas.  Sci.  Rep. 8(1):10104.

Highlighted: Nature India (Rural Indians have healthier guts than urban folks)
https://www.natureasia.com/en/nindia/article/10.1038/nindia.2018.88

Highlighted: The week (That Gut Feeling)
https://www.theweek.in/health/cover/2020/01/10/that-gut-feeling.html

Highlighted: Dept. of Biotechnology, GOI (Richness, functions and diversity of the gut microbiome of healthy Indians)
http://www.dbtindia.nic.in/gut-microbiome-of-healthy-indians/

Highlighted: Vigyan Prasar, DST, GOI (A peek into gut of Indians throws up surprises)
http://vigyanprasar.gov.in/isw/peek_into_gut_indians_throwsup_surprises_story.html

Highlighted: The Hindu (What your gut is telling you)
https://www.thehindu.com/sci-tech/health/what-your-gut-is-telling-you/article24485083.ece

Highlighted: Hindustan Times (Vegetarian diet helps keep Indian gut healthy: Study)
https://www.hindustantimes.com/health/vegetarian-diet-helps-keep-indian-gut-healthy-study/story-9fEx1ypTnvOlm1y9zoJKzL.html

Highlighted: Deccan Herald (Scientists map gut microbiota of Indians)
https://www.deccanherald.com/national/scientists-map-gut-microbiota-682983.html



38. Sarkar S., Das B., Banerjee S.K., (2018). Insights into the Human Gut Microbiome and Cardiovascular Diseases. J. Prac. Card. Sci. 2018;4:10-4.



37. Kumar A., Bag S., Das B. (2018) Novel Genetic tool to study the stability of genomic islands. Rec. Pat. Biotech. doi:10.2174/1872208312666180223113618.



2017


36. Das B., Choudhuri S., Srivastava R., Nair G.B., Ramamurthy T. (2017). Fostering research on antimicrobial resistance in India. The BMJ 2017;358:j3535 (IF=27.6)



35. Bag S., Ghosh T.S., Das B. (2017). Complete genome sequence of Faecalibacterium prausnitzii strain Indica isolated from the gut of a healthy adult Indian. Genome Announc. 16;5(46). pii: e01286-17.



34. Bag S., Ghosh T.S., Das B. (2017). Complete genome sequence of Collinsella aerofaciens strain Indica isolated from the gut of a healthy Indian. Genome Announc. 22;5(47). pii: e01361-17.



33. Kumar P., Bag S., Dey P., Ghosh T.S., Dayal M., Saha B., Verma J., Saxena S., Pant A., Kumar D., Desigamani A., Rana P., Hanpude P., Maity T.K., Bhadra R.K., Sharma N.C., Nair G.B., Ramamurthy T., Das B.  (2017). Molecular Insights into Antimicrobial Resistance Traits of Multidrug Resistant Enteric Pathogens isolated from India.  Sci.  Rep. 2017 Oct 31;7(1):14468. (Top 100 read microbiology article for Scientific Reports in 2017).



32. Bag S., Ghosh T.S., Das B. (2017). Whole Genome Sequence of Megasphaera elsdenii strain Indica isolated from the gut of a healthy adult Indian. Genome Announc 5: e01033-17.



31. Das A., Pereira V., Saxena S., Ghosh TS., Anbumani D., Bag S., Das B., Nair GB., Abraham P., Mande SS (2017) Gastric microbiome of Indian patients with Helicobacter pylori infection, and their interaction network. 2017, Sci.  Rep. 2017 Oct 2;3:17067. (Top 100 read microbiology article for Scientific Reports in 2017).



30. Bag S., Ghosh T.S., Das B. (2017). Whole Genome Sequence of Bifidobacterium longum strain Indica isolated from the gut of a healthy adult Indian. Genome Announc. 5: e01017-17.

29.

29. Srivastava N., Shelly A., Kumar M., Pant A., Das B., Majumdar T., Mazumder S. (2017). Aeromonas hydrophila utilizes TLR4 topology for synchronous activation of MyD88 and TRIF to orchestrate anti-inflammatory responses in zebrafish. Cell Death Discv. 2017, 3, 17067.

28.

28. Bag S., Ghosh T., Das B. (2017). Draft Genome Sequence of Prevotella copri isolated from the gut of a healthy adult Indian. Genome Announc. 5:e00834-17.



2016


27. Das B., Pazhani G.P., Sarkar A., Mukhopadhyay A.K., Nair G.B., Ramamurthy T. (2016). Molecular Evolution and Functional Divergence of Vibrio cholerae. Curr. Opin. Infect. Dis. 29(5):520-7.

26.

26. Bag S., Saha B., Mehta O., D. Anbumani, Kumar N., Dayal M., Pant A., Kumar P., Saxena S., AllinK.H., Hansen T., Arumugam M., Vestergaard H.,Pedersen O., Pereira V., Abraham P., Tripathi R., Wadhwa N., Bhatnagar S., PrakashV.G., Radha V., Anjana R. M., Mohan V., Takeda K., Kurakawa T., Nair G.B., Das B.  (2016). An Improved Method For Isolation Of High Quality Community Bacterial DNA From Human And Environmental Samples For Metagenomics Studies. Sci. Rep.6, 26775; doi: 10.1038/srep26775 (Top 100 read article for Scientific Reports in 2016)

25.

25. Rakonjac J., Das B., and Derda R. (2016). Filamentous Bacteriophage in Bio/Nano/Technology, Bacterial Pathogenesis and Ecology. Front. Microbiol. 7:2109.

24.

24. Chowdhury G., Bhadra R.K., Bag S., Pazhani G.P., Das B., Basu P., Nagamani K., Nandy R.K., Mukhopadhyay A.K., Ramamurthy T. (2016).  Rugose atypical Vibrio cholerae O1 El Tor responsible for 2009 cholera outbreak in India. J. Med. Microb. 65: 1130-1136



2015


23. Pant A., Anbumani D., Bag S., Mehta B., Kumar P., Saxena S., Nair G. B., Das B. (2015). Effect of LexA on chromosomal integration of CTXf in Vibrio cholerae. J. Bacteriol.198:268-75.

2014
22.

2014

22. Das B. (2014). Mechanistic Insights Into Filamentous Phage Integration In Vibrio cholerae. Front. Microbiol. 5:650.

21.

21. Das B., Kumari R., Pant A., Sen Gupta S., Saxena S., Nair G.B. (2014). A Novel, Broad-Range, CTXΦ-Derived Stable Integrative Expression Vector For Functional Studies. J. Bacteriol. 196(23): 4071-80.

Highlighted: Times of India (Research roundup: Vector-wise)
https://timesofindia.indiatimes.com/home/education/news/Researcg-roundup-Vector-wise/articleshow/48511390.cms


Highlighted: Dept. of Biotechnology, GOI (Scientists in THSTI Develop Novel Genetic Tools to speed up Drug Discovery Research)
http://www.dbtindia.nic.in/scientists-in-thsti-develop-novel-genetic-tools-to-speed-up-drug-discovery-research/

20. Das B. Banerjee R, Nair G.B., Basak S. (2014). Dynamics in genome evolution of Vibrio cholerae. Infect Genet Evol.23:32-41.

19.

19. Das B., Midonet C.,  Paly E., Barre F.X. (2014). XerD initiates the integration of TLCΦinto the Vibrio cholerae genome independently of FtsK. Proc. Natl. Acad. Sci. USA; 111 (47): 16848-16853.(IF=10.4)

18.

18. Das B., Nair G.B., Bhadra R.K. (2014). Acquisition and dissemination mechanisms of CTXΦ in Vibrio cholerae: New paradigm for dif residents. World J Med Genet. 4: 27-33.



17. Bag S., Das B., Dasgupta S., Bhadra R.K. (2014). Mutational analysis of the (p)ppGpp synthetase activity of the Rel enzyme of Mycobacterium tuberculosis. Arch Microbiol. 196(8):575-88.



16. Kim E.J., Lee D., Moon S.H., Lee C.H., Kim S.J., Lee J.H., Kim, J.O., Song M., Das B., Clemens J.D., Pape J. W., Nair G.B., Kim D.W. (2014) Molecular insights into the evolutionary pathway of Vibrio cholerae O1 atypical El Tor variants. Plos pathogens. 0(9):e1004384.

15.

15. Ghosh T.S., Sen Gupta S., Bhattacharya T., Yadav D., Barik A., Chowdhury A., Das B., Mande S.S., Nair G.B. (2014) Gut Microbiomes of Indian children of varying nutritional status. PLoS One.9:e95547



2013


14. Das B., Martinez E., Midonet C., and Barre F.X. (2013). Integrative mobile elements exploiting Xer recombination. Trends Microbiol. 21:23-30. (IF=11.4)

 

2012

13. Pal R.R., Bag S., Dasgupta S., Das B., Bhadra R.K. (2012). Functional characterization of the stringent response regulatory gene dksA of Vibrio cholerae and its role in modulation of virulence phenotypes. J. Bacteriol.194(20):5638-48.



2011

12. Das B., Bischerour J., Barre F.X. (2011). VGJF integration and excision mechanisms contribute to the genetic diversity of Vibrio cholerae epidemic strains. Proc. Natl. Acad. Sci, USA. 108:2516-2521.(IF=10.4)

.

11. Das B., Bischerour J., Barre F.X. (2011). Molecular mechanism of acquisition of the cholera toxin genes. Indian J. Med. Res. 133:195-200.



10. Pal R.R., Das B., Dasgupta S., Bhadra R.K. (2011). Genetic components of stringent response in Vibrio cholerae. Indian J. Med. Res. 133:212-217.

9. Majumdar T., Das B., Bhadra R.K., Dam B., Mazumder S. (2011). Complete nucleotide sequence of a quinolone resistance gene (qnrS2) carrying plasmid of Aeromonas hydrophila isolated from fish. Plasmid. 66:79-84.



2010

8. Das B., Bischerour J., Val M.E., Barre F.X. (2010) Molecular keys of the tropism of integration of the Cholera Toxin phage. Proc. Natl. Acad. Sci, USA 107:4377-4382. (Commentary in PNAS). (IF=10.4)

7.

7. Halder K., Das B., Nair G. B., Bhadra R.K. (2010). Molecular evidences favouring stepwise evolution of Mozambique Vibrio cholerae O1 El Tor hybrid strain. Microbiology (SGM) 156:99-107.

2009
6.

2009

6. Das B., Pal R.R., Bag S., Bhadra R.K. (2009). Stringent response in Vibrio cholerae: genetic analysis of spoT gene function and identification of a novel (p)ppGpp synthetase gene. Mol. Microbiol. 72:380-398.

2008
5.

2008

5. Das B., Bhadra R.K. (2008). Molecular characterization of Vibrio cholerae ΔrelA ΔspoT double mutants. Arch. Micrbiol. 189:227-238.

4. Shah S., Das B., Bhadra R.K. (2008). Functional analysis of the essential GTP-binding protein coding gene cgtA of Vibrio cholerae. J. Bacteriol. 190:4764-4771.



4. Shah S., Das B., Bhadra R.K. (2008). Functional analysis of the essential GTP-binding protein coding gene cgtA of Vibrio cholerae. J. Bacteriol. 190:4764-4771.

3. Bhowmick R., Ghosal A., Das B., Koley H., Saha D. R., Ganguly S., Nandy R.K., Bhadra R.K., Chatterjee N.S. (2008). Intestinal adherence of Vibrio cholerae involves a coordinated interaction between colonization factor GbpA and mucin. Infect. Immun. 76:4968-4977.



2007
.

2. Das B., Halder K., Pal P., Bhadra R.K. (2007). Small chromosomal integration site of classical CTX prophage in Mozambique Vibrio cholerae O1 biotype El Tor strain. Arch. Micrbiol. 188:677-683.



2006
.

1. Maiti D., Das B., Saha A., Nandy R.K., Nair G.B., Bhadra R.K. (2006). Genetic organization of the pre-CTX and CTX prophages in the genome of an environmental Vibrio cholerae non-O1, non-O139 strain. Microbiology (SGM)152:3633-3641.
 

 

Book/Book Chapter

  • Ramamurthy T., Mukhopadhyay A. Das B., Nandy R., Mutreja A., Weill F.X., Nair G.B. (2020). "Molecular Typing of Vibrio cholerae: Imprints in the Epidemiology of Cholera" in “Molecular Typing in Bacterial Infections” Editors: Ivano de Filippis and Marian L. McKee. Publisher: Springer Nature Publishing.

  • Matta T., Purohit A., Das B. (2020). "Human reproductive tract microbiome and birth outcomes" in “ Recent Advances in Obstetrics and Gynaecology”. Editor: Aruna Nigam. Evangel Publisher. 

  • Das B., Saxena S., Mehta O., Bhadra R.K., Nair G.B. (2019). "The human microbiota in health and disease" in "Probiotics in Health: Emerging Opportunities" (Edited by Takeda Y., Nair G.B., Kurpad A.). Publisher: Wiley India.

  • eBook (2017): Filamentous Bacteriophage in Bio/Nano/Technology, Bacterial Pathogenesis and Ecology. Edited by: Jasna Rakonjac, Bhabatosh Das, Ratmir Derda. Publisher: Frontiers Media SA. ISBN: 9782889450954
  • Dasgupta S., Das B., Basu P., Bhadra R.K. (2016) Molecular basis of stringent response in Vibrio cholerae (Edited by Frans J. de Bruijn. John Wiley & Sons, Inc, USA). P. 507-516 Aug 2016
  • Nair G.B., Sen Gupta S., Das B.(2014). The “Uncultured” but significant world of the human gut microbiome: New metagenomic insights. In G. P. Talwar and L.M. Srivastava (Eds.), Textbook of Biochemistry and Human Biology (pp. 664-671). Delhi, India: PHI Learning Pvt. Ltd.
  • Das B.and Nair G.B. (2012). The genomics of Cholera. In ‘Genomics Applications for the Developing World’ (Eds. Karen E. Nelson & Barbara jones-Nelson) Springer publication, USA pp. 21-38, DOI: 10.1007/978-1-4614-2182-5_3.
  • Bhadra R.K., Shah S., Das B.(2010). Small Molecule Signaling Systems in Vibrio cholerae.  In ‘Epidemiological and Molecular Aspects on Cholera’ (Eds. Ramamurthy T. & Bhattacharya S. K.). Humana Press, USA, pp. 185-201.
  • Bhadra R.K. and Das B.(2008). Coordinated regulation of gene expression in Vibrio cholerae. In ‘Vibrio cholerae: Genomics and Molecular Biology’ (Eds. Faruque, S.M. & Nair, G.B). Caister Academic Press, UK, pp. 153-167.

Bhabatosh Das, Archana Pant, Jyoti Verma, Shailendra Vyas: Title: Integrative Expression Vector. Patent application no. 201911046890; Year: 2019.

  • Young Scientist Award from International Life Sciences Institute-India for Improving Public Health in the Areas of Food Safety, Nutrition and Wellbeing (2021)

  • BMGF Travel Grant Award to attend 52nd US-Japan Joint Panel Conference on Cholera and Other Bacterial Enteric Infections (2018)
  • Japan Society for the Promotion of Science (JSPS) Invitational Fellowship Award (2017). 

  • Invited Member in World Health Organization (WHO) Expert Group for Developing “Target Product Profile for cholera Rapid Diagnostic Tests, 2017
  • Young Investigator Award (1st prize) from Yakult India Microbiota and Probiotic Science Foundation, 2016

 

Editoral Board Member

  • Microbial Ecology (Editoreal Board Member)
  • Gut Microbiome (Editoreal Board Member)
  • Frontiers in Microbiology (Guest Associate Editor)
  • Frontiers in Genetics (Guest Associate Editor)
  • EC Microbiology (Editoreal Board Member)

 

  • Best Poster Award in Conference/Symposium

 •    Best Poster Award (2018) in Biozest 2018 for research on the CTX-phage replication and integration. Organizers: South Asian University, New Delhi on 6th December 2018.
      Title: Deciphering the host bacterial factors essential for integration and replication of CTX-phage
      Presenting author: Archana Pant, Corresponding author: Bhabatosh Das.

•    Best Poster Award (2018) in the international Probiotic Symposium “Probiotics through the Lifespan” for research on the Gut Microbiome and Antimicrobial resistance (24th-25th November 2018).
Organizers:  NICED, Kolkata; ILDS, Kolkata; Amity University, Kolkata.         
     Title: Gut microbiome is the epicenter for dissemination of antimicrobial resistance traits
     Presenting author: Jyoti Verma, Corresponding author: Bhabatosh Das.

•    Best Poster Award (2018) for Antimicrobial resistance research in the international Probiotic Symposium, “ Probiotics through the Lifespan” (24-25 Nov. 2018). Organizers: NICED, Kolkata; ILDS, Kolkata; Amity University, Kolkata.
     Title: Role of gut microbiota in the emergence of colistin resistant enteric pathogens
     Presenting author: Tarosi Senapati, Corresponding author: Bhabatosh Das.      

•    Best Poster Award (2018) 
in the International Symposium on Infectious Diseases (12-14 November) for Antimicrobial resistance research. Organizer: Regional Centre for Biotechnology, Faridabad and Jamia Hamdard, Delhi.
     Title: Insights into the resistance traits of multidrug resistant enteric pathogens isolated from India
     Presenting author: Satyabrata Bag, Corresponding author: Bhabatosh Das.  

•    Best Poster Award (2018)  in the International Conference on Anti‐Microbial Resistance (16-17 Feb. 2018) for Antimicrobial resistance research. Organizer: NIPER, Kolkata and NICED Kolkata.
     Title: Molecular insights into antimicrobial resistance traits of multi drug resistant commensal human gut microbiota
     Presenting author: Satyabrata Bag, Corresponding author: Bhabatosh Das.  

•    Best Poster Award (2018) in the NIPGR and THSTI Open day (28th September) for Antimicrobial resistance research.
     Title: Antibiotic resistance in commensal and pathogenic bacteria
     Presenting author: Jyoti Verma, Corresponding author: Bhabatosh Das.
 
•    Best Poster Award (2017)
in “Cardiovascular Research Convergence” conference on 12th and 19th August 2017 for Human Microbiome research . Organizers: AIIMS-Delhi and THSTI-Faridabad.
     Title: Gut Microbiome in Inflammatory Bowel Disease: A Comparative analysis in the Indian population
     Presenting author: Tarini Shankar Ghosh. Corresponding author: Bhabatosh Das

•    Best Poster Award (2017)  in “THSTI foundation day for Human Microbiome research. Organizer: THSTI.
     Title: Insights into the Gut Microbiome of Inflammatory Bowel Disease patients living in different parts of India
     Presenting author: Tarini Shankar Ghosh. Corresponding author: Bhabatosh Das.

 

Invited Talks

Guest Speaker (Webinar talk 2021)Organized by the Calcutta University on 1st March 2021.

Title: Genetic nature and dynamics of antibiotic resistance traits in the commensal and pathogenic enteric bacteria

Guest Speaker (Webinar talk 2021)Organized by the Amrtita Vishwa Vidyapeetham on 26 February 2021.

Title: Genomics of Extensively Drug Resistant Enteric Bacterial Pathogens Isolated from India

Guest Speaker (Webinar talk 2021): Organized by the Savitribai Phule Pune University, Pune on 2nd February 2021

 

Title: Understanding role of human gut microbiome in the emergence and spread of antibiotic resistant enteric bacterial pathogens

Guest Speaker (2020, webinar talk): Organised by the Dept. of Gastroenterology, AIIMS New Delhi on 18th August 2020

Title: Homeostasis and Dysbiosis of the Human Gut Microbiome in Health and Diseases

Guest Speaker (2020, webinar talk): Organised by the School of Biotechnology, Presidency University, Kolkata on 6-7 August 2020

Title: Human Microbiome in Health and Diseases

Guest Speaker (2020, webinar talk): Organised by the Dept. of Science and Technology (DST), Govt. of Rajasthan on 12th April 2020

Title: Human Microbiome in Health and Diseases

Guest Speaker (2020, webinar talk): Organised by the Sidho-Kanho-Birsha-University, WB on 8th June 2020

Title: Molecular insights into COVID-19 and its pathogen SARS-CoV-2

Guest Speaker (2020, webinar talk): Organised by the Adamas University, Kolkata on 6th July 2020.

Title: Gut Microbiome: Associations, Functions and Implications for therapeutics

Guest Speaker (2020): 10th India probiotic symposium on “Cutting edge science and applications: Intestinal microbiota and Probiotics” organized by the Probiotic Science Foundation on 29th February-1st March 2020 at The Suryaa, New Delhi.

Title: Diet and the Gut Microbiome: Applications, Functions and Implications for Therapeutics.

Keynote Speaker (2019): Seminar on "Current Challenges of antimicrobial Resistance and Potential Intervention by Bacteriophages" organized by the ICMR-NICED on 16th and 17th September at Hyatt Regency Kolkata.

Title: Insights into Antimicrobial Resistance in Human Associated Microbes.

Guest Speaker (2019): International India|EMBO Symposium on Human Microbiome organized by J. Craig Venter Institute, US and National Institute of Biomedical Genomics, IN on 9-12 Nov, 2019.

Title: Role of vaginal microbiome in preterm birth

Guest Speaker (2019): National seminar on Next Generation DNA sequencing organized by Pondicherry University, India on 12-13 Dec, 2019.

Title: Next Generation Sequencing Technology and Application.

Guest Speaker (2019): National Institute of Pharmaceutical Education and Research (NIPER) Kolkata on 7th November 2019.

Title: Insights into antibiotic resistance in human associated gut microbiota

Guest Speaker  (2019): Frontiers in Biological Sciences. Organizers: (i) St. Xavier's College, (ii) Presidency University (iii) CSIR-IICB, Kolkata.

Title: Understanding the role of human gut microbiome in the emergence of antibiotic resistant enteric bacterial pathogens

Guest Speaker (2019):  Workshop on Translational Health at The International Centre for Genetic Engineering and Biotechnology (ICGEB), New Delhi on 11th - 15th March 2019.

Title: Structure, functions and dynamics of gut microbiome of Indian population living in rural and urban areas.

Guest Speaker (2019): All India Institute of Medical Sciences (AIIMS), New Delhi (2nd March. 2019)

Title: Metagenomics

Guest Speaker (2019):  All India Institute of Medical Sciences (AIIMS), New Delhi (23rd Feb. 2019)

Title: Human Microbiome: Concept, Approaches and Implications

Guest Speaker (2018): 59th Annual Conference of Association of Microbiologist of India & International Symposium on Host Pathogen Interactions organized at University of Hyderabad on 9-12 December 2018.

Title: Role of Gut Microbiota of Healthy Human in the Emergence of Resistance Pathogens

Guest Speaker (2018): International Conference on “Role of Probiotics in Promoting Healthy Microbiome for Health and Immunity” organized by International Life Science Institute-India, New Delhi on 6th December 2018.

Title:Impact of Microbial Community DNA Extraction Method on Human Microbiome Study

Guest Speaker (2018): 9th India Probiotic Symposium organized by the Gut Microbiota and Probiotic Science Foundation in association with Amity University, Kolkata, National Institute of Cholera and Enteric Diseases (NICED), Kolkata and the Indian Institute of Liver and Digestive Sciences, Kolkata on 24th - 25th November 2018.

Title: GutMicrobiome of Healthy Indian Population Living in Urban and Rural Areas

Guest Speaker (2018): International Conference on Microbiome Research (ICMR) 2018, National Centre For Cell Science, Pune on 19th - 22nd November 2018.

Title:Gut Microbiome of Indian Population in Health and Diseases

Guest Speaker (2018): Institute of Life Sciences, Bhubaneswar 4th September 2018.

Title: Gut Microbiome of Indian Population in Health and Diseases

Guest Speaker (2018): Workshop and seminar on Translational research in biomedical and agricultural sciences, All India Institute of Medical Sciences, New Delhi, 6th – 7th July 2018.

Title:Molecular Insights into Antimicrobial Resistance Traits of Human Gut Microbiota

Guest Speaker (2018): Manipal Academy of Higher Education, Manipal 14th March 2018

Title: Current Understanding of the Human Microbiome

Guest Speaker (2018): Current trends in Genomics at Aligarh Muslim University, Aligarh on 21 March 2018.

Title: Genomics of commensal and pathogenic enteric bacteria: AMR perspectives

Guest Speaker (2018): NASH-context and Research at Indian Institute of liver and digestive Sciences, Kolkata on 6th February 2018.

Title: Microbiome and Metabolic Diseases

Guest Speaker (2017): Graduate School of Medicine, Osaka University, Japan on 27th October 2017.

Title: Insights into Gut Microbiome of Indian Population in Health and Diseases

Speaker and organizing secretary (2017): Indo-US Workshop on Genomics and Bioinformatics to Explore Human Microbial Ecology in Health and Diseasesorganized by THSTI on September 6th-8th 2017.

Title:Human Microbiome Research in THSTI: Understanding and Challenges

Guest Speaker (2017): at national conference onCardiovascular Research Convergence Organized by AIIMS-Delhi and THSTI-Faridabad on 12th August 2017. 

Title:Diversity, stability and resilience of human gut microbiota

Guest Speaker ((2017)): Faculty Development Programme at Kalinga Institute of Medical Sciences (KIMS) KIIT University, Bhubneswar, 29th June 2017

Title: Dysbiosis: How to measure it and its association with various diseases

Guest Speaker (2017): Institute of Post-Graduate Medical Education & Research, Kolkata on 26th May 2017

Title:Microbiome in Liver diseases

Guest Speaker (2017): at National Institute of Science Education and Research (NISER), 7th February 2017

Title: Antimicrobial Resistant Enteric Pathogens: Molecular Insights into Resistance Traits of Isolates from Indian

Guest Speaker (2017): at National Institute of Science Education and Research (NISER), 6th February 2017

Title: Gut microbiome of the Indian Population: Current Understanding and Future Challenges

Guest Speaker (2017): SUPERBUGS V/S SUPERDRUGS: The Looming Global Antibiotic Resistance Crisis, Amrita School of Biotechnology, Amritapuri, Kollam, Kerala (19th to 20th January 2017)

Title:Multidrug Resistant Enteric Pathogens: Molecular Insights into Resistance Traits of Isolates from Indian

Guest Speaker (2016): 40th Annual Conference of Indian Association of Medical Microbiologists, PGIMER, Chandigarh (23rd to 27th November 2016)

Title: Microbiome of the Indian Population: Current Understanding and Future Challenges

Young Investigator Presentation (2016): Probiotics in Health-Emerging Opportunities, Chennai (3rd to 4th December 2016)

Title: The Gut Microbiome of Healthy Indians: Findings and Challenges

Invited participant (2016): WHO Global Workshop on Strengthening Integrated Surveillance of Foodborne Diseases and Antimicrobial Resistance through the Whole Genome Sequencing methods.(4th to 8th April 2016)

Venue: Thammasat University, Bangkok, Thailand

Selected Participant (2016): Advance Course on Antibiotics (AdCAb). Les Pensieres, France, (9th to 20th October 2016)

Guest Speaker (2016): 3rd Biennial Conference & International Symposium on Stress, Microbiome & Probiotics, NISER Bhubneswar, Odisha (11-13 March 2016)

Title: Antimicrobial Resistant Enteric Pathogens: Genomics Advances and Future Perspectives

Guest Speaker (2015) : 56th Annual Conference of Association of Microbiologists of India (AMI 2015), JNU, New Delhi (7th-10th December 2015)

Title:Antibiotic resistance: Molecular insights into resistance traits of human enteric pathogens

Guest Speaker (2015): Provocative ideas on Human Placental Biology;Department of Biotechnology, Ministry of Science and Technology, Govt. of India, New Delhi.(1st -2nd December 2015)

Title:Placental microbiome and its role in pregnancy outcomes

Guest Speaker (2015): International workshop on applications of systems and mathematical biology in public health, NISER, Bhubneswar.(22nd -24th February 2015)

Title:Guanosine penta- and tetraphosphate metabolisms in bacteria and implications in gut microbiota homeostasis

Guest Speaker (2014): Indo-German Bilateral Workshops on “Diagnostics of Translational Genome Sequencing in Clinical and Public Health Microbiology” Organized by the Madras Medical Mission (MMM), Chennai, India.(19th-21stMarch 2014)

Title:Functional Metagenomics: Dissemination of Antibiotic Resistance Traits in Bacterial Pathogens

(1) Nutra Ingradients USA (24 September 2018)

Title: Microbiome insights

https://www.nutraingredients-usa.com/Article/2018/09/24/NutraIngredients-USA-Global-Round-up-Increasing-B2-production-Amway-in-India-and-more

 

(2) The Hindu (26th August 2018)

Title: A nursery of drug resistance

https://www.thehindu.com/sci-tech/health/a-nursery-of-drug-resistance/article24782373.ece

 

(3) BusinessLines (21st August 2018)

Gut bacteria are a reservoir of drug resistance genes: study

https://www.thehindubusinessline.com/news/science/gut-bacteria-are-a-reservoir-of-drug-resistance-genes-study/article24744954.ece

 

(4) Nature India(29 July 2018)

Pathogens pick up drug resistance genes from friendly bacteria

https://www.natureasia.com/en/nindia/article/10.1038/nindia.2018.95

 

(5) Nature India (July11, 2018)

Rural Indians have healthier guts than urban folks

https://www.natureasia.com/en/nindia/article/10.1038/nindia.2018.88

 

(6) Dept. of Biotechnology, Govt. of India (July 23, 2018)

Richness, functions and diversity of the gut microbiome of healthy Indians

http://www.dbtindia.nic.in/gut-microbiome-of-healthy-indians/

 

(7) Vigyan Prasar, Dept. of Science and Technology, Govt. of India (July 19, 2018)

A peek into gut of Indians throws up surprises

http://vigyanprasar.gov.in/isw/peek_into_gut_indians_throwsup_surprises_story.html

 

(8) The Hindu (July 22, 2018)

What your gut is telling you

https://www.thehindu.com/sci-tech/health/what-your-gut-is-telling-you/article24485083.ece

 

(9) Hindustan Times (July 22, 2018)

Vegetarian diet helps keep Indian gut healthy: Study

https://www.hindustantimes.com/health/vegetarian-diet-helps-keep-indian-gut-healthy-study/story-9fEx1ypTnvOlm1y9zoJKzL.html

 

(10) Deccan Herald (23rd July, 2018)

Scientists map gut microbiota of Indians

https://www.deccanherald.com/national/scientists-map-gut-microbiota-682983.html

 

(11) The Hindu (15th October 2017)

We need to talk about AMR

https://www.thehindu.com/todays-paper/tp-opinion/we-need-to-talk-about-amr/article19864066.ece

 

(12) Fountain ink (17th May 2017)

The body’s secret garden: How the exploration of the microbiome is going to change face of medicine

https://fountainink.in/reportage/the-body039s-secret-garden

 

(13) Dept. of Biotechnology, Govt. of India (2015)

Scientists in THSTI Develop Novel Genetic Tools to speed up Drug Discovery Research

http://www.dbtindia.nic.in/scientists-in-thsti-develop-novel-genetic-tools-to-speed-up-drug-discovery-research/

 

(14) Times of India (Aug 17, 2015)

Research roundup: Vector-wise

https://timesofindia.indiatimes.com/home/education/news/Researcg-roundup-Vector-wise/articleshow/48511390.cms

 

(14) Times of India (Aug 17, 2015)

Research roundup: Vector-wise

 

https://timesofindia.indiatimes.com/home/education/news/Researcg-roundup-Vector-wise/articleshow/48511390.cms

 

MS. JYOTI VERMA
RESEARCH FELLOW

MR. PAWAN KUMAR
PH.D STUDENT

MS. AYUSHI PUROHIT
PH.D STUDENT

MR. ATTESH
LAB ATTENDENT

MS. AKANSHA KOTHIDAR
RESEARCH FELLOW

DR. PALLAVI SINHA
MICROBIOLOGIST

MS. SHRUTI PANWAR
JUNIOR RESEARCH FELLOW

MS. PRIYANKA CHAKRAVARTI
LAB TECHNICIAN

MS. SHASHI KUMARI
PH.D STUDENT

MS. MEENAL CHAWLA
PH.D STUDENT