
DR.SUSMITA CHAUDHURI
Ph.D.
ASSISTANT PROFESSOR
- Ph.D., National Institute of Cholera & Enteric Diseases, University of Calcutta.
- M.Sc., University of Calcutta.
- B.Sc., Presidency College, University of Calcutta.
Areas of Expertise
- Molecular basis of viable-but-non-culturable (VBNC) bacteria
- Biomarker discovery by genomics, epigenomics, proteomics, metabolomics
- Diagnostic and alternative therapeutic interventions for antimicrobial resistance
- Monoclonal antibody based therapeutic innovation for bacterial infections
Research Interests/ Research Summary
Our present research interest is focused on anti-microbial resistance (AMR) by developing innovative diagnostics and drug delivery formulations for bacterial infections. We emphasize on a multi-pronged approach to tackle AMR with rapid, point of care diagnostics, improved formulations for controlling hospital acquired infections and developing alternetive to antibiotics. We also delve into in depth mechanistic studies of viable-but-non-culturable (VBNC) cells relevant to bacterial species critical for human health.
Research Experience
- Scientist D, Centre for Biodesign and Diagnostics, THSTI, 2018-2019
- Scientist C, Centre for Biodesign and Diagnostics, THSTI, 2011-2018
- Senior Scientist in Biopharmaceutical R&D, Panacea Biotec Ltd., New Delhi (2007-2011)
- Postdoctoral Fellow in Department of Medical Microbiology & Immunology, University of Alberta, Canada (2005-2007)
Publication
- Longitudinal serology in SARS-CoV-2 infected individuals in India – a prospective cohort study. Ramachandran Thiruvengadam,…..Susmita Chaudhuri….Shinjini Bhatnagar. The American Journal of Tropical Medicine and Hygiene. Am. J. Trop. Med. Hyg., 105(1), 2021, pp. 66–72
- Comparative evaluation of SARS-CoV-2 IgG immunoassays in India, Susmita Chaudhuri et.al., J Clin Virol, 2020, 24;131:104609..
- Essential laboratory diagnostic at each level of health laboratory services in South East Asia region. Susmita Chaudhuri et. al., World Health Organization, 2020 (In press).
- Das B, Chaudhuri S*, Srivastava R, Nair GB, Ramamurthy T. Fostering Research into Antimicrobial Research In India. British Medical Journal. 2017. 358: j3535. (Co-corresponding)
- Kumar N, Gupta DG, Kumar S, Maurya P, Tiwari A, Mathew B, Banerjee S, Hadlar S, Pillai J, Bhatnagar S and Chaudhuri S. Exploring packaged microvesicle proteome composition of Chinese Hamster Ovary secretome. J Bioprocess Biotech. 2016. 6:274.
- Chaudhuri S, Maurya P, Kaur M, Tiwari A, Borth N, Bhatnagar S and Kumar N. Investigation of CHO Secretome: Potential Way to Improve Recombinant Protein Production from Bioprocess . 2015. J Bioprocess Biotech 2015, 5:7
- S Chaudhuri, ... L J. Guilbert. Human cytomegalovirus interacts with TLR2 and CD14 on syncytiotrophoblasts to stimulate TNFαmRNA & apoptosis. Placenta. 2009. 30:994-1001.
- Chaudhuri S, ... Naik TN. Molecular epidemiology of HCV infection among acute and chronic liver disease patients in Kolkata, India. J Clin Virol. 2005 Jan;32(1):38-46.
- S. Das, V. Varghese, S. Chaudhuri, ...T. N. Naik.. Genetic variability of human rotavirus strains isolated from Eastern and Northern India. J Med Virol. 2004 Jan; 72 (1): 156-61.
- P. Barman, S. Ghosh, S. Das, V. Varghese, S. Chaudhuri, ...T.N. Naik. Sequencing and sequence analysis of VP7 and NSP5 genes reveal emergence of new genotype of bovine Group B rotaviruses in India. J Clin Microbiol. 2004 Jun; 42 (6): 2816-2818.
- Das S, Varghese V, Chaudhuri S, ... Naik TN. Emergence of Novel Human Group A Rotavirus G12 Strains in India. J Clin Microbiol 2003; 41: 2760-2762.
- Chowdhury A, Santra A, Chaudhuri S, ... Mazumdar DNG. Hepatitis C virus Infection in General Population: A Community Based Study in West Bengal, India. Hepatology 2003; 37: 802-809.
- Das S, Sen A, Uma G, Varghese V, Chaudhuri S, ....Naik TN. Genomic Diversity of Group A Rotavirus Strains Infecting Humans in Eastern India. J Clin Microbiol 2002; 40: 146-149.
- Method of improving stability of recombinant protein product in CHO batch culture by selective removal of metalloproteinase rich exosomal fraction and uses thereof (2015)
- Method of flow cytometry based rapid antimicrobial susceptibility testing and uses thereof (2017)
- Discontinuous lateral flow test strip and method (2018)
- Novel oxone-based sanitizer protect against toxic pathogens (2020)
- Novel Fenton reagent-based sanitizer protect against toxic pathogens (2020)
- Biofilm inhibiting sol-gel composition for coating on substrates and process of preparing the same (2021)
- Antimicrobial biofilm containing silver nanoparticles (2021)
1. Development and evaluation of a rapid phenotypic antimicrobial susceptibility test for clinical use; BIRAC; 2019-2021
2. Novel Eco-friendly Nano-composite Coatings for Prevention of Surgical Site Infections; DBT; 2019-2022
3. Emerging drug resistance of uropathogens in community acquired urinary tract infection and molecular insights into dynamics of resistance traits in Indian isolates- A pan-India multi-centric study; ICMR; 2019-2022
4. Community testing of COVID-19 in Mumbai; BMGF-BIRAC; 2021-2021
· Tie-BIRAC award for Women in Entrepreneurial Research, 2018.
· NIH-Fogarty fellowship on Indo-US Framework Program on Global Health Innovation, sponsored by NIH-Fogarty International Centre for Microfluidics and Imaging training at Tufts University, Boston, USA, 2017.
· Biotechnology Ignition Grant award for the development of ‘Rapid Point-of-care field deployable typhoid diagnostics’ by BIRAC, 2017.
· MFN Strategic Training Programme fellowship, Perinatal Research Centre, University of Alberta, Canada, 2006-2007.
· 'Best Poster Award'; Poster entitled 'Molecular Epidemiology of HCV Infection among Acute and Chronic Liver Disease Patients in Kolkata'; VI-Sir Dorabji Tata Symposium on Viral Hepatitis at the Indian Institute of Science, Bangalore, India, on March 10-11, 2005.
· National Scholarship (1997-98) of the Gov. of India on the result of B.Sc. (Zoology Hons.) Examination of Calcutta University.
· 'Sarasibala Chaudhuri' scholarship in the year 1997 for ranking 1st Class 2nd in Calcutta University in B.Sc. (Zoology Hons.) Exam.
Entrepreneurial Venture:
Co-Founder of Tritek Innovation Pvt. Ltd., based in THSTI Interim Incubation Centre, NCR Biotech Science Cluster, Faridabad.
MS.MANISHA YADAV
PH.D STUDENT
MR.SUBHASH CHANDRA TANWAR
TECHNICAL OFFICER-I
MS.SWETA PANDEY
PH.D STUDENT
MS.DEBRUPA SARKAR
PROJECT ASSOCIATE-I
MS.SIMRAN BABBAR
RESEARCH FELLOW
- SUSMITA[AT]THSTI[DOT]RES[DOT]IN