Thsti - Translational Health Science and Technology Institute

भारत सरकार के विज्ञान एवम प्रौदयोगिकी मंत्रालय के जैव प्रौदयोगिकी विभाग की स्वायत्त संस्थान
AN AUTONOMOUS INSTITUTE OF DEPT. OF BIOTECHNOLOGY, MINISTRY OF SCIENCE AND TECHNOLOGY, GOVT OF INDIA

होम
संकाय प्रोफ़ाइल

DR.BHABATOSH DAS

M.Sc., M.Tech., Ph.D., FAScT

PROFESSOR

2022: Fellow of West Bengal Academy of Science and Technology
2017: JSPS Fellow, Osaka University, Japan
2008-2011: CNRS Postdoctoral Fellow, The Institute of Integrative Biology of the Cell, France
2006-2008: CSIR Research Fellow, Indian Institute of Chemical Biology, India
2003-2006: ICMR Research Fellow, Indian Institute of Chemical Biology, India
2001-2003: M.Tech., Biotech. & Biochem. Eng., IIT-Kharagpur, India

Currently, my lab is working to understand the genome and genetics of microbial community associated with (a) Gastroenteritis (b) Sepsis (c) Term and preterm birth.

(a) Genomics of bacterial pathogens: We are investigating the (i) genome compositions and functions of bacterial pathogens associated with SEPSIS, DIARRHOEA and GASTRIC CANCER (ii) Emergence of antimicrobial resistant bacterial pathogens. In addition, our lab is actively involved in engineering bacterial genome for developing reporter strains to screen compound library and identify hit molecules that will help to restore the efficacy of existing antibiotics against drug resistant bacterial pathogens, specially Gram-negative ESKAPE pathogens.

Vision: Identify potential target and hit molecules for developing antibiotic potentiators.

(b) Alternative to Antibiotics: Extensive drug-resistant bacterial pathogens drastically reduce the efficacy of most of the routinely used antibiotics in the health sector. Antimicrobial resistant crisis is a urgent situation that needs immediate attention. An alternative to antibiotics to tackle drug-resistant bacterial pathogens is a potential option. We are working on the discovery and development of bacteriophage-based biotherapeutics to treat extensively drug-resistant bacterial pathogens responsible for sepsis, urinary tract infections, respiratory tract infections, and gastro-intestinal tract infections. We have isolated hundreds of bacteriophages that can eliminate Acinetobacter baumannii, Klebsiella pneumoniae, Pseudomonas aeruginosa, Escherichia coli, Vibrio cholerae, and Neisseria gonorrhoeae from the infection sites. Currently, we are developing effective bacteriophage coktails to use it against blood-stream infections, respiratory tract infections, and gastro-intestinal tract infections.

Vision: Develop an effective phage cocktail to treat extensive drug-resistant bacterial infections.

(c) Reproductive tract microbiome: We are decoding the metagenomics sequences Indian women enrolled in the GARBH-Ini pregnancy cohort. Our major focus is oriented to understand the (i) role of vaginal microbiota in the birth outcomes (ii) specific microbial genomic signatures associated with birth outcomes. We have isolated different Lactobacillus species from the vaginal milieu of Indian women. Currently, decoding their genome sequences and looking for functions associated with inflammation, anti-inflammation, antimicrobial and antimicrobial resistance.

Vision: Understand the biology of preterm birth (PTB) and role of vaginal microbiota in PTB.

Publication

2024

97. Deka A, KumarN, Basu S, Chawla M, Bhattacharya N, Ali SK, Madan U, Kumar S, Das B, Sengupta D, Awasthi A, Basak S(2024) Non-canonical NF-kB signaling limits the tolerogenic b-catenin-Raldh2 axis in gut dendritic cells. EMBO J (Accepted).

96. Arunan B, Talukdar D, Swain S, Varadarajan A, Sarda R, Singh G, Nischal N, Soneja M, Bakshi S, Jana P, Tanwar S, Sikka K, Verma H, Subramanian A, Xess I, Wig N, Das B*, Ray A (2024) Metagenomic insights into fungal community composition of the nasopharyngeal region of COVID associated mucormycosis patients from India. J. Med. Virol. 2024 Apr; 96(4): e29601.doi: 10.1002/jmv.29601. *Corresponding author

95. Purohit A., Kandiyal B, Kumar S, Pragasam AK, Kamboj P, Talukdar D, Verma J, Sharma V,Sarkar S, Mahajan D, Yadav R, Ahmed R, Nanda R, Dikshit D, Banerjee SK, Shalimar, Das B (2024)Genomic repertoires of Collinsella aerofaciens linked with increased ethanol production and liver inflammation in NAFLD. iScience 27, 108764, February 16, 2024 https://doi.org/10.1016/j.isci.2023.108764 (Corresponding author).

94. Wadhwa K, Malik S, Srinigila B, [Others], Wadhwa N, Das B, Garg PK, (2024) Correlation of severity and clinical outcomes of COVID-19 with virus variants: A prospective, multicentre hospital network study. Ind. J. Med. Res. 159(1):p 91-101.

2023

93. Mehrotra T., Konar D., Pragasam AK., Kumar S.,Jana P., Babele P., Paul D.,Purohit A.,Tanwar S., Bakshi S., Das S., Verma J., Talukdar D.,Narendrakumar L., Kothidar A., Karmakar SP., Chaudhuri S., Pal S., Jain K., Srikanth CV., Sankar JS., Atmakuri K., Agarwal R., Gaind R., Ballal M., Kammili N., Bhadra RK, Ramamurthy T., Nair GB. Das B. (2023). Antimicrobial resistance heterogeneity among multidrug-resistant Gram-negative pathogens: Phenotypic, Genotypic and Proteomic analysis. Proc. Natl. Acad. Sci. U S A (2023 Aug 15;120(33):e2305465120. doi: 10.1073/pnas.2305465120. Epub 2023 Aug 7. PMID: 37549252; PMCID: PMC10434301. (Corresponding author).

92. Saikrishna K, Talukdar D, Das S, Bakshi S, Chakravarti P, Jana P, Karmakar S, Wig N, Ray A, Das B* (2023) Study on effects of probiotics on whole gut microbiome and clinical course in patients with critical care illnesses. Microbial Ecology. 2023 May 3. doi: 10.1007/s00248-023-02224-8. Epub ahead of print. PMID: 37133495. (Corresponding author).

91. Saha M, Pragasam AK, Kumari S, Verma J, Das B, Bhadra RK (2023) Genomic and functional insights into antibiotic resistance genes floR and strA-linked with SXT element of Vibrio cholerae non-O1/non-O139. Microbiology (SGM), DOI 10.1099/mic.0.001424 (Corresponding author).

90. Talukdar D, Bandopadhyay P, Ray Y, Paul SR, Sarif J, D’Rozario R, Lahiri A, Bhowmick D, Chatterjee S, Das B, Ganguly D (2023) Association of gut microbial dysbiosis with disease severity, response to therapy and disease outcomes in Indian patients with COVID-19. Gut Pathogens. 15(1):22. doi: 10.1186/s13099-023-00546-z. PMID: 37161621; PMCID: PMC10170741. (Corresponding author).

89. Paul D, Chawla M, Ahrodia T, Narendrakumar L, Das B (2023) Antibiotic potentiators against macrolide resistance: Discovery and development. Antibiotics 2023, 12(12), 1715; https://doi.org/10.3390/antibiotics12121715

88. Das B*, Mahajan D, Rakonjac J (2023). Editorial: Antibiotic Potentiators Against Drug-Resistant Pathogens: Discovery, Development and Clinical Applications. Frontiers in Microbiology. doi.org/10.3389/fmicb.2023.1173906.(Corresponding author).

87. Panwar S, Kumari S, Verma J, Bakshi S, Lekshmi N, Paul D, Das B. (2023) Toxin linked mobile genetic elements in major enteric bacterial pathogens. Gut Microbiome. doi.org/10.1017/gmb.2023.2 (Corresponding author).

86. Das B^#, Chowdhury G^#, Pant A, Kumar S, Mukherjee P, Koley H, Okamoto K, Ramamurthy T, Dutta S, Mukhopadyay A (2023) Genomic Insights into An Extensively Drug Resistant Pseudomonas aeruginosa Isolated from Diarrhea Case in Kolkata, India. Future Microbiology doi.org/10.2217/fmb-2022-0140. (# Contributed equally).

85. Lekshmi N, Chakraborty M, Kumari S, Paul D, Das B (2023) β-Lactam potentiators to re-sensitize resistant pathogens: Discovery, development, clinical use and the way forward. Frontiers in Microbiol. 13:1092556. doi: 10.3389/fmicb.2022.1092556.

84. Pant A, Das B, Arimbasseri GA (2023) Host Microbiome in tuberculosis: Disease, treatment, and immunity perspectives. Front. Microbiol. Volume 14; doi: 10.3389/fmicb.2023.1236348

83. Taneja J, Chatterjee K, Sasidharan J, Abbas SZ, Rai AK, Raychaudhury S, Das B, Das A (2023) Post-COVID-19 Rhino-Orbito-Cerebral mucormycosis: A clinicomycological study from North India. Medical Mycology, myad067, https://doi.org/10.1093/mmy/myad067

82. Nii T, Maeda Y, Motooka D, Naito M, Matsumoto Y, Ogawa T, Oguro-Igashira E, Kishikawa T, Yamashita M, Koizumi S, Kurakawa T, Okumura R, Kayama H, Murakami M, Sakaguchi T, Das B, Nakamura S, Okada Y, Kumanogoh A, Takeda K (2023) Genomic repertoires linked with pathogenic potency of arthritogenic Prevotella copri isolated from the gut of rheumatoid arthritis patients. Annals of the Rheumatic Diseases. 2023;82:621-629. doi:10.1136/annrheumdis-2022-222881.

81. Rizvi ZA, Adhikari N, Sharma K, Sadhu S, Dandotiya J, Khatri R, Singh V, Vinayake Das V, Das B, Medigeshi G, Mani S, Pandey AK, Bhatnagar S, Samal S, Garg PK, Awasthi A, (2023) Omicron sub-lineage BA.5 infection causes attenuated pathology and results in robust protection in Omicron recovered hACE2 transgenic mice. Communications Biology (Accepted).

80. Deshpande S, Ansari M, Sutar J, Das P, Hingankar N, Mukherjee S, Jayal P, Singh S, Anantharaj A, Singh J, Chattopadhyay S, Raghavan S, Gosain M, Chauhan S, Shrivas S, Prasad C, Chauhan S, Sharma N, Jana P, Thiruvengadam R, Kshetrapal P, Wadhwa N, Das B, Batra G, Medigeshi G, Sok D, Bhatnagar S, Garg P, Bhattacharya J (2023). Ancestral SARS-CoV-2 driven antibody repertoire diversity in an unvaccinated individual correlates with expanded neutralization breadth. Microbiology Spectrum. doi.org/10.1128/spectrum.04332-22.

2022

79. Kumar S, Mehrotra T, Talukdar T, Verma J, Karmakar BC, Paul P, Choudhuri S, Kumari AP, Bakshi S, Kumari S, Chawla M, Purohit A, Karmakar SP, Mutreja A, Banerjee S, Ray A, Ramamurthy T, Mukhopadyay AK, Das D* (2022) Region-specific Genomic Signatures of Multidrug-Resistant Helicobacter pylori Isolated from East and South India. GENE 2022 Dec 30;847:146857. doi: 10.1016/j.gene.2022.146857. (Correponding Author)

78. Pant A, Maiti TK, Mahajan D, Das B* (2022) Human Gut Microbiota and Drug Metabolism. Microbial Ecology. 2022 Jul 23:1-15. doi: 10.1007/s00248-022-02081-x (Correponding Author)

77. Chawla M, Verma J, Gupta R, Das B* (2022) Antibiotic Potentiators against Multidrug-resistant Bacteria: Discovery, Development and Clinical Relevance. Front. Microbiol. 2022 Jul 1;13:887251. doi: 10.3389/fmicb.2022.887251 (Corresponding author)

76. Biswas Q, Purohit A, Kumar A, Rakshit D, Maiti D, Das B*, Bhadra RK, (2022) Genetic and mutational analysis of virulence traits and its modulation in an environmental toxigenic Vibrio cholerae non-O1/non-O139 strain VCE232. Microbiology, SGM (UK). doi: 10.1099/mic.0.001135 (Corresponding author)

75. Ramamurthy T, Pragasam AK, Brown TA, Will RC, Vasudevan K, Das B, Srivastava SK, Chowdhury G, Mukhopadhyay AK, Dutta S, Veeraraghavan B, Thomson NR, Sharma NC, Nair GB, Takeda Y, Ghosh A, Dougan G, Mutreja A (2022) Vibrio cholerae O139 genomes provide a clue to why it failed to usher in the eighth cholera pandemic. Nature Communication (Accepted)

74. Chowdhury G, Ramamurthy T, Das B, Ghosh D, Okamoto K, Miyoshi S, Dutta S, Mukhopadhyay A (2022) Characterization of NDM-5 Carbapenemase-Encoding Gene (blaNDM-5)-Positive Multidrug Resistant Commensal Escherichia coli from Diarrheal Patients. Infn. Drug Resist. 2022:15 1–12

73. Pavan S, Prabhu AN, Gorthi SP, Das B, Mutreja A, Shetty V, Ramamurthy T, Ballal M (2022) Exploring the multifactorial aspects of Gut Microbiome in Parkinson’s Disease. Folia Microbiologica 2022 May 18. doi: 10.1007/s12223-022-00977-2.

72. Yadav YK, Banerjee SK, Das B, Chaudhary K (2022) Editorial: System biology and Omics approaches for understanding complex disease biology. Front. Genet. doi: 10.3389/fgene.2022.896818

71. Medigeshi M., Batra G, Murugesan D.R., Thiruvengadam R., Chattopadhyay S., Das B., Gosain M., Ayushi, Singh J., Anbalagan A., Shaman H., Pargai K., Mehdi F., Das S.J., Kahlon N., Singh S., Kshetrapal P., Wadhwa N., Pandey A.K., Bhatnagar S., Garg P.K. (2022) Sub-optimal Neutralisation of Omicron (B.1.1.529) Variant by Antibodies induced by Vaccine alone or SARS-CoV-2 Infection plus Vaccine (Hybrid Immunity) post 6-months. eBioMedicine. doi.org/10.1101/2022.01.04.22268747

70. Bir R, Gautam H, Arif N, Verma J., Banerjee S, Tyagi S, Mohapatra S, Sood S, Dhawan B, Chaudhry R, Kapil A, Das BK, Das B (2022) Analysis of Colistin resistance in Carbapenem-Resistant Enterobacterales and XDR Klebsiella pneumoniae. Therapeutic Advances in Infectious Disease. doi:10.1177/20499361221080650

69. Aggarwal H, Pathak P, Singh V, Kumar Y, Shankar M, Das B, Jagavelu K, Dikshit M (2021) Vancomycin-induced modulation of Gram-positive gut bacteria and metabolites remediate insulin resistance in iNOS knockout mice. Front Cell Infect Microbiol. 19 January 2022DOI:10.21203/rs.3.rs-826534/v1

2021

68. MehrotraT, Devi TB, Kumar S, Talukdar D, Karmakar SP, Kothidar A, Verma J, Kumari S, Alexander SM, Retnakumar RJ, Devadas K, Ray A, Mutreja A, Nair GB, Chattopadhyay S, Das B (2021) Antimicrobial resistance and virulence in Helicobacter pylori: Genomic insights. Genomics.2021 Oct 5;113(6):3951-3966(Corresponding Author)

67. KumarS,KumariN, Talukdar D, Kothidar A, Sarkar M, Mehta O, Kshetrapal P, Wadhwa N, Thiruvengadam R, Desiraju BK, GARBH-Ini study group, Nair GB, Bhatnagar S, Mukherjee S, Das B, (2021)The Vaginal Microbial Signatures of Preterm Birth Delivery in Indian Women. Front Cell Infect Microbiol.2021 April,doi: 10.3389/fcimb.2021.622474 (Corresponding Author)

66. Pinna NK, Anjana RM, Saxena S, Dutta A, Gnanaprakash V, Rameshkumar G, Aswath S, Raghavan S, Rani CSS, Radha V, Balasubramanyam M, Pant A, Nielsen T, Jørgensen T, Færch K, Kashani A, Silva MCA, Vestergaard H, Hansen TH, Hansen T, Arumugam M, Nair GB, Das B., Pedersen O, Mohan V, Mande SS. Trans-ethnic gut microbial signatures of prediabetic subjects from India and Denmark. Genome Med. 2021 Mar 3;13(1):36. doi: 10.1186/s13073-021-00851-9. PMID: 33658065; PMCID: PMC7931552. (Corresponding Author)

65. Das B, Dutta S, Ghosh TS, Kumar S, Kushal RK, Ray P, Suri, V, Nair GB (2021) Human milk microbiome of healthy lactating North Indian mothers is dominated by genus Pseudomonas. Journal of Human Lactation. 2021 Sep 28:8903344211048415.PMID: 34581614

64. Chowdhury G, Senapati T, Das B, Kamath A, Pal D, Bose P, Deb A, Paul S, Mukhopadhyay AK, Dutta S, Ramamurthy T (2021) Laboratory evaluation of the rapid diagnostic tests for the detection of Vibrio cholerae O1 using diarrheal samples. 2021 May, PLOS Neg. Trop. Dis. 2021 Jun 15;15(6):e0009521. doi: 10.1371/journal.pntd.0009521. PMID: 34129602.

63. Kumar M, Kumar J, Sharma S, Hussain A, Shelly A, Das B, Mazumder S (2021) TLR22-mediated activation of TNF--caspase-1/IL-1 inflammatory axis leads to apoptosis of Aeromonas hydrophila-infected macrophages. Molecular Immunology. S0161-5890(21)00206-6

62. Alvarez-Silva C, Kashani A, Hansen TH, Pinna NK, Anjana RM, Dutta A, Saxena S, Støy J, Kampmann U, Nielsen T, Jørgensen T, Gnanaprakash V, Gnanavadivel R, Sukumaran A, Rani CSS, Færch K, Radha V, Balasubramanyam M, Nair GB, Das B. Vestergaard H, Hansen T, Mande SS, Mohan V, Arumugam M, Pedersen O. Trans-ethnic gut microbiota signatures of type 2 diabetes in Denmark and India. Genome Med. 2021 Mar 3;13(1):37. doi: 10.1186/s13073-021-00856-4. PMID: 33658058; PMCID: PMC7931542.

61. Will RC, Ramamurthy T, Sharma NC, Veeraraghavan B, Sangal L, Haldar P, Pragasam AK, Vasudevan K, Kumar D, Das B. Heinz E, Melnikov V, Baker S, Sangal V, Dougan G, Mutreja A. Spatiotemporal persistence of multiple, diverse clades and toxins of Corynebacterium diphtheriae. Nat. Commun. 2021 Mar 8;12(1):1500. doi: 10.1038/s41467-021-21870-5. PMID: 33686077; PMCID: PMC7940655.

60. Devi TB, Devadas K, George M, Gandhimathi A, Chouhan D, Retnakumar RJ, Alexander SM, Varghese J, Dharmaseelan S, Chandrika SK, Jissa VT, Das B.Nair GB, Chattopadhyay S. Low Bifidobacterium Abundance in the Lower Gut Microbiota Is Associated With Helicobacter pylori-Related Gastric Ulcer and Gastric Cancer. Front Microbiol. 2021 Feb 26;12:631140. doi: 10.3389/fmicb.2021.631140. PMID: 33717022; PMCID: PMC7953064.

2020

59. Pant A, Bag S, Saha B, Verma J, Kumar P, Banerjee S, Kumar B, Kumar Y, Desigamani A, Maiti S, Maiti TK, Banerjee SK, Bhadra RK, Koley H, Dutta S, Nair GB, Ramamurthy T, Das B. Molecular insights into the genome dynamics and interactions between core and acquired genomes of Vibrio cholerae. Proc Natl Acad Sci U S A. 2020 Sep 22;117(38):23762-23773. doi: 10.1073/pnas.2006283117. Epub 2020 Sep 1. PMID: 32873641; PMCID: PMC7519391.(Corresponding author)

58. Das B.Bhadra RK. (p)ppGpp Metabolism and Antimicrobial Resistance in Bacterial Pathogens. Front Microbiol. 2020 Oct 9;11:563944. doi: 10.3389/fmicb.2020.563944. PMID: 33162948; PMCID: PMC7581866.(Corresponding author)

57. Rakshit D, Dasgupta S, Das B, Bhadra RK. Functional Insights Into the Role of gppA in (p)ppGpp Metabolism of Vibrio cholerae. Front Microbiol. 2020 Sep 29;11:564644. doi: 10.3389/fmicb.2020.564644. PMID: 33117311; PMCID: PMC7552824.(Corresponding author)

56. Kumar A, Das B., Kumar N. Vibrio Pathogenicity Island-1: The Master Determinant of Cholera Pathogenesis. Front Cell Infect Microbiol. 2020 Oct 6;10:561296. doi: 10.3389/fcimb.2020.561296. PMID: 33123494; PMCID: PMC7574455.(Corresponding author)

55. Kedia S, Ghosh TS, Jain S, Desigamani A, Kumar A, Gupta V, Bopanna S, Yadav DP, Goyal S, Makharia G, Travis SPL, Das B. Ahuja V. Gut microbiome diversity in acute severe colitis is distinct from mild to moderate ulcerative colitis. J. Gastroenterol Hepatol. 2021 Mar;36(3):731-739. doi: 10.1111/jgh.15232. Epub 2020 Sep 14. PMID: 32870508.(Corresponding author)

54. Mehta O, Ghosh TS, Kothidar A, Gowtham MR, Mitra R, Kshetrapal P, Wadhwa N, Thiruvengadam R; GARBH-Ini study group, Nair GB, Bhatnagar S, Das B. Vaginal Microbiome of Pregnant Indian Women: Insights into the Genome of Dominant Lactobacillus Species. Microb Ecol. 2020 Aug;80(2):487-499. doi: 10.1007/s00248-020-01501-0. Epub 2020 Mar 23. PMID: 32206831.(Corresponding author)

53. Chatterjee P, Nagi N, Agarwal A, Das B, Banerjee S, Sarkar S, Gupta N, Gangakhedkar RR. The 2019 novel coronavirus disease (COVID-19) pandemic: A review of the current evidence. Indian J Med Res. 2020 Feb & Mar;151(2 & 3):147-159. doi: 10.4103/ijmr.IJMR_519_20. PMID: 32362642; PMCID: PMC7357405.

2019

52. Das B.Insights into TLCΦ lysogeny: A twist in the mechanism of IMEX integration. Proc Natl Acad Sci U S A. 2019 Sep 10;116(37):18159-18161. doi: 10.1073/pnas.1912633116. Epub 2019 Aug 22. PMID: 31439815; PMCID: PMC6744843.(Corresponding author)

51. Das B.Chattoraj DK. Commentary: Functionality of Two Origins of Replication in Vibrio cholerae Strains With a Single Chromosome. Front Microbiol. 2019 Jun 19;10:1314. doi: 10.3389/fmicb.2019.01314. PMID: 31275259; PMCID: PMC6594386.

50. Ramamurthy T, Mutreja A, Weill FX, Das B. Ghosh A, Nair GB. Revisiting the Global Epidemiology of Cholera in Conjunction With the Genomics of Vibrio cholerae. Front Public Health. 2019 Jul 23;7:203. doi: 10.3389/fpubh.2019.00203. Erratum in: Front Public Health. 2019 Aug 23;7:237. PMID: 31396501; PMCID: PMC6664003.

49. Pareek S, Kurakawa T, Das B, Motooka D, Nakaya S, Rongsen-Chandola T, Goyal N, Kayama H, Dodd D, Okumura R, Maeda Y, Fujimoto K, Nii T, Ogawa T, Iida T, Bhandari N, Kida T, Nakamura S, Nair GB, Takeda K. Comparison of Japanese and Indian intestinal microbiota shows diet-dependent interaction between bacteria and fungi. NPJ Biofilms Microbiomes. 2019 Dec 20;5(1):37. doi: 10.1038/s41522-019-0110-9. PMID: 31885873; PMCID: PMC6925221.

48. Das B,Verma J, Kumar P, Ghosh A, Ramamurthy T. Antibiotic resistance in Vibrio cholerae: Understanding the ecology of resistance genes and mechanisms. Vaccine. 2020 Feb 29;38 Suppl 1:A83-A92. doi: 10.1016/j.vaccine.2019.06.031. Epub 2019 Jul 2. PMID: 31272870.(Corresponding author)

47. Pant A, Das B, Bhadra RK. CTX phage of Vibrio cholerae: Genomics and applications. Vaccine. 2020 Feb 29;38 Suppl 1:A7-A12. doi: 10.1016/j.Vaccine. 2019.06.034. Epub 2019 Jul 1. PMID: 31272871.(Corresponding author)

46.Ramamurthy T, Das B, Chakraborty S, Mukhopadhyay AK, Sack DA. Diagnostic techniques for rapid detection of Vibrio cholerae O1/O139. Vaccine. 2020 Feb 29;38 Suppl 1:A73-A82. doi: 10.1016/j.vaccine.2019.07.099. Epub 2019 Aug 16. PMID: 31427135.

45. Das B.Nair GB. Homeostasis and dysbiosis of the gut microbiome in health and disease. J Biosci. 2019 Oct;44(5):117. PMID: 31719226.(Corresponding author)

44. Senapati T, Kothidar A, Banerjee SK, Das B. Insights into the gastrointestinal tract microbiomes of Indian population. J Biosci. 2019 Oct;44(5):113. PMID: 31719222.(Corresponding author)

43. Sharma NC, Efstratiou A, Mokrousov I, Mutreja A, Das B, Ramamurthy T. Diphtheria. Nat Rev Dis Primers. 2019 Dec 5;5(1):81. doi: 10.1038/s41572-019-0131-y. PMID: 31804499.

42. Verma J, Bag S, Saha B, Kumar P, Ghosh TS, Dayal M, Senapati T, Mehra S, Dey P, Desigamani A, Kumar D, Rana P, Kumar B, Maiti TK, Sharma NC, Bhadra RK, Mutreja A, Nair GB, Ramamurthy T, Das B. Genomic plasticity associated with antimicrobial resistance in Vibrio cholerae. Proc Natl Acad Sci U S A. 2019 Mar 26;116(13):6226-6231. doi: 10.1073/pnas.1900141116. Epub 2019 Mar 13. PMID: 30867296; PMCID: PMC6442563.(Corresponding author)

41.Adela R, Reddy PNC, Ghosh TS, Aggarwal S, Yadav AK, Das B, Banerjee SK. Serum protein signature of coronary artery disease in type 2 diabetes mellitus. J Transl Med. 2019 Jan 24;17(1):17. doi: 10.1186/s12967-018-1755-5. PMID: 30674322; PMCID: PMC6345069.

2018

40. Das B,Ghosh TS, Kedia S, Rampal R, Saxena S, Bag S, Mitra R, Dayal M, Mehta O, Surendranath A, Travis SPL, Tripathi P, Nair GB, Ahuja V. Analysis of the Gut Microbiome of Rural and Urban Healthy Indians Living in Sea Level and High Altitude Areas. Sci Rep. 2018 Jul 4;8(1):10104. doi: 10.1038/s41598-018-28550-3. PMID: 29973712; PMCID: PMC6031670.(Corresponding author)

39. Bag S, Ghosh TS, Banerjee S, Mehta O, Verma J, Dayal M, Desigamani A, Kumar P, Saha B, Kedia S, Ahuja V, Ramamurthy T, Das B. Molecular Insights into Antimicrobial Resistance Traits of Commensal Human Gut Microbiota. Microb Ecol. 2019 Feb;77(2):546-557. doi: 10.1007/s00248-018-1228-7. Epub 2018 Jul 16. PMID: 30009332.(Corresponding author)

38. Sarkar S., Das B., Banerjee S.K., (2018). Insights into the Human Gut Microbiome and Cardiovascular Diseases. J. Prac. Card. Sci.2018;4:10-4. (Corresponding author)

37. Kumar A, Bag S, Das B. Novel Genetic Tool to Study the Stability of Genomic Islands. Recent Pat Biotechnol. 2018;12(3):200-207. doi: 10.2174/1872208312666180223113618. PMID: 29473528.(Corresponding author)

2017

36. Das B,Chaudhuri S, Srivastava R, Nair GB, Ramamurthy T. Fostering research into antimicrobial resistance in India. BMJ. 2017 Sep 6;358:j3535. doi: 10.1136/bmj.j3535. PMID: 28877874; PMCID: PMC5582344.(Corresponding author)

35. Bag S, Ghosh TS, Das B. Complete Genome Sequence of Faecalibacterium prausnitzii Isolated from the Gut of a Healthy Indian Adult. Genome Announc. 2017 Nov 16;5(46):e01286-17. doi: 10.1128/genomeA.01286-17. PMID: 29146862; PMCID: PMC5690339.(Corresponding author)

34. Bag S, Ghosh TS, Das B. Complete Genome Sequence of Collinsella aerofaciens Isolated from the Gut of a Healthy Indian Subject. Genome Announc. 2017 Nov 22;5(47):e01361-17. doi: 10.1128/genomeA.01361-17. PMID: 29167267; PMCID: PMC5701492.(Corresponding author)

33. Kumar P, Bag S, Ghosh TS, Dey P, Dayal M, Saha B, Verma J, Pant A, Saxena S, Desigamani A, Rana P, Kumar D, Sharma NC, Hanpude P, Maiti TK, Mukhopadhyay AK, Bhadra RK, Nair GB, Ramamurthy T, Das B. Molecular Insights into Antimicrobial Resistance Traits of Multidrug Resistant Enteric Pathogens isolated from India. Sci Rep. 2017 Oct 31;7(1):14468. doi: 10.1038/s41598-017-14791-1. PMID: 29089611; PMCID: PMC5663842.(Corresponding author)

32. Bag S, Ghosh TS, Das B. Whole-Genome Sequence of a Megasphaera elsdenii Strain Isolated from the Gut of a Healthy Indian Adult Subject. Genome Announc. 2017 Oct 19;5(42):e01033-17. doi: 10.1128/genomeA.01033-17. PMID: 29051237; PMCID: PMC5646390.(Corresponding author)

31. Das A, Pereira V, Saxena S, Ghosh TS, Anbumani D, Bag S, Das B, Nair GB, Abraham P, Mande SS. Gastric microbiome of Indian patients with Helicobacter pylori infection, and their interaction networks. Sci Rep. 2017 Nov 13;7(1):15438. doi: 10.1038/s41598-017-15510-6. PMID: 29133866; PMCID: PMC5684312. (Top 100 read microbiology article for Scientific Reports in 2017).

30. Bag S, Ghosh TS, Das B. Whole-Genome Sequence of Bifidobacterium longum Strain Indica, Isolated from the Gut of a Healthy Indian Adult. Genome Announc. 2017 Oct 12;5(41):e01017-17. doi: 10.1128/genomeA.01017-17. PMID: 29025929; PMCID: PMC5637489.(Corresponding author)

29.Srivastava N, Shelly A, Kumar M, Pant A, Das B, Majumdar T, Mazumder S. Aeromonas hydrophila utilizes TLR4 topology for synchronous activation of MyD88 and TRIF to orchestrate anti-inflammatory responses in zebrafish. Cell Death Discov. 2017 Oct 2;3:17067. doi: 10.1038/cddiscovery.2017.67. PMID: 29142761; PMCID: PMC5680545.

28. Bag S, Ghosh TS, Das B. Draft Genome Sequence of Prevotella copri Isolated from the Gut of a Healthy Indian Adult. Genome Announc. 2017 Sep 14;5(37):e00834-17. doi: 10.1128/genomeA.00834-17. PMID: 28912310; PMCID: PMC5597751.(Corresponding author)

2016

27. Das B,Pazhani GP, Sarkar A, Mukhopadhyay AK, Nair GB, Ramamurthy T. Molecular evolution and functional divergence of Vibrio cholerae. Curr Opin Infect Dis. 2016 Oct;29(5):520-7. doi: 10.1097/QCO.0000000000000306. PMID: 27537830.

26. Bag S, Saha B, Mehta O, Anbumani D, Kumar N, Dayal M, Pant A, Kumar P, Saxena S, Allin KH, Hansen T, Arumugam M, Vestergaard H, Pedersen O, Pereira V, Abraham P, Tripathi R, Wadhwa N, Bhatnagar S, Prakash VG, Radha V, Anjana RM, Mohan V, Takeda K, Kurakawa T, Nair GB, Das B. An Improved Method for High Quality Metagenomics DNA Extraction from Human and Environmental Samples. Sci Rep. 2016 May 31;6:26775. doi: 10.1038/srep26775. PMID: 27240745; PMCID: PMC4886217.(Corresponding author)

25. Rakonjac J, Das B, Derda R. Editorial: Filamentous Bacteriophage in Bio/Nano/Technology, Bacterial Pathogenesis and Ecology. Front Microbiol. 2016 Dec 23;7:2109. doi: 10.3389/fmicb.2016.02109. PMID: 28066406; PMCID: PMC5179506.

24. Chowdhury G, Bhadra RK, Bag S, Pazhani GP, Das B, Basu P, Nagamani K, Nandy RK, Mukhopadhyay AK, Ramamurthy T. Rugose atypical Vibrio cholerae O1 El Tor responsible for 2009 cholera outbreak in India. J Med Microbiol. 2016 Oct;65(10):1130-1136. doi: 10.1099/jmm.0.000344. Epub 2016 Aug 25. PMID: 27561681.

2015

23. Pant A, Anbumani D, Bag S, Mehta O, Kumar P, Saxena S, Nair GB, Das B. Effect of LexA on Chromosomal Integration of CTXÏ• in Vibrio cholerae. J Bacteriol. 2015 Oct 26;198(2):268-75. doi: 10.1128/JB.00674-15. PMID: 26503849; PMCID: PMC4751795.(Corresponding author)

2014

22. Das B. Mechanistic insights into filamentous phage integration in Vibrio cholerae. Front Microbiol. 2014 Nov 28;5:650. doi: 10.3389/fmicb.2014.00650. PMID: 25506341; PMCID: PMC4246890.(Corresponding author)

21. Das B, Kumari R, Pant A, Sen Gupta S, Saxena S, Mehta O, Nair GB. A novel, broad-range, CTXΦ-derived stable integrative expression vector for functional studies. J Bacteriol. 2014 Dec;196(23):4071-80. doi: 10.1128/JB.01966-14. Epub 2014 Sep 15. PMID: 25225263; PMCID: PMC4248877.(Corresponding author)

20. Banerjee R, Das B, Balakrish Nair G, Basak S. Dynamics in genome evolution of Vibrio cholerae. Infect Genet Evol. 2014 Apr;23:32-41. doi: 10.1016/j.meegid.2014.01.006. Epub 2014 Jan 23. PMID: 24462909.

19. Midonet C, Das B, Paly E, Barre FX. XerD-mediated FtsK-independent integration of TLCÏ• into the Vibrio cholerae genome. Proc Natl Acad Sci U S A. 2014 Nov 25;111(47):16848-53. doi: 10.1073/pnas.1404047111. Epub 2014 Nov 10. PMID: 25385643; PMCID: PMC4250166.

18. Das B., Nair G.B., Bhadra R.K. (2014). Acquisition and dissemination mechanisms of CTXΦ in Vibrio cholerae: New paradigm for dif residents. World J Med Genet. 4: 27-33.

17. Bag S, Das B, Dasgupta S, Bhadra RK. Mutational analysis of the (p)ppGpp synthetase activity of the Rel enzyme of Mycobacterium tuberculosis. Arch Microbiol. 2014 Aug;196(8):575-88. doi: 10.1007/s00203-014-0996-9. Epub 2014 May 24. PMID: 24859914.

16. Kim EJ, Lee D, Moon SH, Lee CH, Kim SJ, Lee JH, Kim JO, Song M, Das B, Clemens JD, Pape JW, Nair GB, Kim DW. Molecular insights into the evolutionary pathway of Vibrio cholerae O1 atypical El Tor variants. PLoS Pathog. 2014 Sep 18;10(9):e1004384. doi: 10.1371/journal.ppat.1004384. PMID: 25233006; PMCID: PMC4169478.

15.Ghosh TS, Gupta SS, Bhattacharya T, Yadav D, Barik A, Chowdhury A, Das B, Mande SS, Nair GB. Gut microbiomes of Indian children of varying nutritional status. PLoS One. 2014 Apr 24;9(4):e95547. doi: 10.1371/journal.pone.0095547. PMID: 24763225; PMCID: PMC3999041.

2013

14. Das B, Martínez E, Midonet C, Barre FX. Integrative mobile elements exploiting Xer recombination. Trends Microbiol. 2013 Jan;21(1):23-30. doi: 10.1016/j.tim.2012.10.003. Epub 2012 Nov 2. PMID: 23127381.

2012

13. Pal RR, Bag S, Dasgupta S, Das B, Bhadra RK. Functional characterization of the stringent response regulatory gene dksA of Vibrio cholerae and its role in modulation of virulence phenotypes. J Bacteriol. 2012 Oct;194(20):5638-48. doi: 10.1128/JB.00518-12. Epub 2012 Aug 17. PMID: 22904284; PMCID: PMC3458680.

2011

12. Das B, Bischerour J, Barre FX. VGJphi integration and excision mechanisms contribute to the genetic diversity of Vibrio cholerae epidemic strains. Proc Natl Acad Sci U S A. 2011 Feb 8;108(6):2516-21. doi: 10.1073/pnas.1017061108. Epub 2011 Jan 24. PMID: 21262799; PMCID: PMC3038760.

11. Das B,Bischerour J, Barre FX. Molecular mechanism of acquisition of the cholera toxin genes. Indian J Med Res. 2011 Feb;133(2):195-200. PMID: 21415494; PMCID: PMC3089051.

10.Pal RR, Das B, Dasgupta S, Bhadra RK. Genetic components of stringent response in Vibrio cholerae. Indian J Med Res. 2011 Feb;133(2):212-7. PMID: 21415497; PMCID: PMC3089054.

9. Majumdar T, Das B, Bhadra RK, Dam B, Mazumder S. Complete nucleotide sequence of a quinolone resistance gene (qnrS2) carrying plasmid of Aeromonas hydrophila isolated from fish. Plasmid. 2011 Jul;66(2):79-84. doi: 10.1016/j.plasmid.2011.05.001. Epub 2011 Jun 12. PMID: 21664930.

2010

8. Das B, Bischerour J, Val ME, Barre FX. Molecular keys of the tropism of integration of the cholera toxin phage. Proc Natl Acad Sci U S A. 2010 Mar 2;107(9):4377-82. doi: 10.1073/pnas.0910212107. Epub 2010 Jan 21. PMID: 20133778; PMCID: PMC2840090.

7. Halder K, Das B, Nair GB, Bhadra RK. Molecular evidence favouring step-wise evolution of Mozambique Vibrio cholerae O1 El Tor hybrid strain. Microbiology (Reading). 2010 Jan;156(Pt 1):99-107. doi: 10.1099/mic.0.032458-0. Epub 2009 Oct 1. PMID: 19797359.

2009

6. Das B,Pal RR, Bag S, Bhadra RK. Stringent response in Vibrio cholerae: genetic analysis of spoT gene function and identification of a novel (p)ppGpp synthetase gene. Mol Microbiol. 2009 Apr;72(2):380-98. doi: 10.1111/j.1365-2958.2009.06653.x. Epub 2009 Mar 4. PMID: 19298370.

2008

5. Das B,Bhadra RK. Molecular characterization of Vibrio cholerae DeltarelA DeltaspoT double mutants. Arch Microbiol. 2008 Mar;189(3):227-38. doi: 10.1007/s00203-007-0312-z. Epub 2007 Oct 30. PMID: 17968531.

4. Shah S, Das B, Bhadra RK. Functional analysis of the essential GTP-binding-protein-coding gene cgtA of Vibrio cholerae. J Bacteriol. 2008 Jul;190(13):4764-71. doi: 10.1128/JB.02021-07. Epub 2008 May 2. PMID: 18456812; PMCID: PMC2446790.

3. Bhowmick R, Ghosal A, Das B, Koley H, Saha DR, Ganguly S, Nandy RK, Bhadra RK, Chatterjee NS. Intestinal adherence of Vibrio cholerae involves a coordinated interaction between colonization factor GbpA and mucin. Infect Immun. 2008 Nov;76(11):4968-77. doi: 10.1128/IAI.01615-07. Epub 2008 Sep 2. PMID: 18765724; PMCID: PMC2573318.

2007

2. Das B,Halder K, Pal P, Bhadra RK. Small chromosomal integration site of classical CTX prophage in Mozambique Vibrio cholerae O1 biotype El Tor strain. Arch Microbiol. 2007 Dec;188(6):677-83. doi: 10.1007/s00203-007-0275-0. Epub 2007 Jul 6. PMID: 17618421.

2006

1.Maiti D, Das B, Saha A, Nandy RK, Nair GB, Bhadra RK. Genetic organization of pre-CTX and CTX prophages in the genome of an environmental Vibrio cholerae non-O1, non-O139 strain. Microbiology (Reading). 2006 Dec;152(Pt 12):3633-3641. doi: 10.1099/mic.0.2006/000117-0. PMID: 17159216.

BOOK/BOOK CHAPTERS

21. Ahrodia T, Kandiyal B, Das B. Microbiota and epigenetics: Health impact. Prog Mol Biol Transl Sci. 2023;198:93-117. doi: 10.1016/bs.pmbts.2023.03.018. Epub 2023 May 4. PMID: 37225326.

20. Das B. (2022). An introduction to human microbiome. Prog Mol Biol Transl Sci. 2022;191(1):1-28. doi: 10.1016/bs.pmbts.2022.06.026. Epub 2022 Jul 30. PMID: 36270674.

19. Pant A, Das B. (2022). Microbiome-based therapeutics: Opportunity and challenges. Prog Mol Biol Transl Sci. 2022;191(1):229-262. doi: 10.1016/bs.pmbts.2022.07.006. Epub 2022 Aug 22. PMID: 36270680.

18.Paul D., Das B. (2022). Gut microbiome in the emergence of antibiotic-resistant bacterial pathogens. Prog Mol Biol Transl Sci. 2022;192(1):1-31. doi: 10.1016/bs.pmbts.2022.07.009. Epub 2022 Sep 3. PMID: 36280316.

17. Ahrodia T, Das S, Bakshi S, Das B. (2022). Structure, functions, and diversity of the healthy human microbiome. Prog Mol Biol Transl Sci. 2022;191(1):53-82. doi: 10.1016/bs.pmbts.2022.07.003. Epub 2022 Aug 18. PMID: 36270682.

16. Ahrodia T, Yodhaanjali JR, Das B. (2022). Vaginal microbiome dysbiosis in preterm birth. Prog Mol Biol Transl Sci. 2022;192(1):309-329. doi: 10.1016/bs.pmbts.2022.08.001. Epub 2022 Sep 11. PMID: 36280323.

15. Chawla M, Gupta R, Das B. (2022). Gut microbiome dysbiosis in malnutrition. Prog Mol Biol Transl Sci. 2022;192(1):205-229. doi: 10.1016/bs.pmbts.2022.07.011. Epub 2022 Aug 30. PMID: 36280320.

14. Kandiyal B, Ahuja V, Takeda K, Das B. (2022). Gut microbiome dysbiosis in inflammatory bowel disease. Prog Mol Biol Transl Sci. 2022;192(1):179-204. doi: 10.1016/bs.pmbts.2022.09.003. Epub 2022 Oct 3. PMID: 36280319.

13. J, Sankar MJ, Atmakuri K, Agarwal R, Das B. (2022).Gut microbiome dysbiosis in neonatal sepsis. Prog Mol Biol Transl Sci. 2022;192(1):125-147. doi: 10.1016/bs.pmbts.2022.07.010. Epub 2022 Aug 30. PMID: 36280317.

12. A, Alam MJ, Kandiyal B, Shalimar, Das B., Banerjee SK. (2022) Gut microbiome and non-alcoholic fatty liver disease. Prog Mol Biol Transl Sci. 2022;191(1):187-206. doi: 10.1016/bs.pmbts.2022.07.004. Epub 2022 Aug 22. PMID: 36270678.
11. Alam MJ, Puppala V, Uppulapu SK, Das B., Banerjee SK. (2022) Human microbiome and cardiovascular diseases. Prog Mol Biol Transl Sci. 2022;192(1):231-279. doi: 10.1016/bs.pmbts.2022.07.012. Epub 2022 Sep 11. PMID: 36280321.
10. Ahrodia T., Wadhwa N., Das B.(2021) Gut Microbiome Signatures in Health and Diseases. Elsevier Food Science, ISBN 9780081005965, doi.org/10.1016/B978-0-12-819265-8.00067-X

9. Ramamurthy T., Mukhopadhyay A. Das B.Nandy R., Mutreja A., Weill F.X., Nair G.B. (2020) Molecular Typing of Vibrio cholerae:Imprints in the Epidemiology of Cholerain“Molecular Typing in Bacterial Infections” Editors: Ivano de Filippis and Marian L. McKee. Publisher: Springer Nature Publishing. ISBN: 978-1-62703-185-1

8. Matta T., Purohit A., Das B. (2020). "Human reproductive tract microbiome and birth outcomes" in “Recent Advances in Obstetrics and Gynaecology”. Editor: Aruna Nigam. Evangel Publisher.

7. Das B.,Saxena S., Mehta O., Bhadra R.K., Nair G.B. (2019). The human microbiota in health and disease. In Probiotics in Health: Emerging Opportunities (Edited by Takeda Y., Nair G.B., Kurpad A.). Publisher: Wiley India.

6. eBook (2017): Filamentous Bacteriophage in Bio/Nano/Technology, Bacterial Pathogenesis and Ecology. Edited by: Rakonjac J., Das B., Derda R. Publisher: Frontiers Media SA. ISBN: 9782889450954
5. Dasgupta S., Das B.,Basu P., Bhadra R.K. (2016) Molecular basis of stringent response in Vibrio cholerae (Edited by Frans J. de Bruijn. John Wiley & Sons, Inc, USA). P. 507-516 Aug 2016

4. Nair G.B., Sen Gupta S., Das B. (2014). The “Uncultured” but significant world of the human gut microbiome: New metagenomic insights. In G. P. Talwar and L.M. Srivastava (Eds.), Textbook of Biochemistry and Human Biology (pp. 664-671). Delhi, India: PHI Learning Pvt. Ltd.

3. Das B.and Nair G.B. (2012). The genomics of Cholera. In ‘Genomics Applications for the Developing World’ (Eds. Karen E. Nelson & Barbara jones-Nelson) Springer publication, USA pp. 21-38, DOI: 10.1007/978-1-4614-2182-5_3.

2. Bhadra R.K., Shah S., Das B.(2010). Small Molecule Signaling Systems in Vibrio cholerae. In ‘Epidemiological and Molecular Aspects on Cholera’ (Eds. Ramamurthy T. & Bhattacharya S. K.). Humana Press, USA, pp. 185-201.

1. Bhadra R.K. and Das B. (2008). Coordinated regulation of gene expression in Vibrio cholerae. In ‘Vibrio cholerae: Genomics and Molecular Biology’ (Eds. Faruque, S.M. & Nair, G.B). Caister Academic Press, UK, pp. 153-167.

Abstract

1. D Paul, J Verma, B Das (2023) A Rapid Point-of-Care Dipstick Assay for Differentiation of Sars-Cov-2 Variants in Covid-19 Patients. International Journal of Infectious Diseases 130, S24

2. J Taneja, R Ranjan, K Chatterjee, V Ramesh, B Das (2022) Phaeohyphomycosis caused by Rhinocladiella similis mimicking Sporotrichosis. Medical Mycology 60 (S1), 167

3. J Taneja, K Chatterjee, J Sasidharan, Z Abbas, AK Rai, B Das (2022) Clinical outcome and in vitro antifungal susceptibility of clinical isolates of rhino-orbito-cerebral mycosis associated with post COVID 19 from North India

Bhabatosh Das, Lekshmi N., Chawla M, Paul D. Title: Genetically engineered bacterial reporter strain and a method of preparing the same there of. Patent application no. 202411035814. Year: 2024

Bhabatosh Das, Shruti Panwar, Nitya Wadhwa, Roshan Kumar: Title: Universal microbial sample transport medium for genomic and metagenomic studies. Patent application no. 202211023269. Year: 2022

Bhabatosh Das, Archana Pant, Jyoti Verma, Shailendra Vyas: Title: Integrative Expression Vector. Patent application no. 201911046890; Year: 2019.

S. Ramachandran National Bioscience Award (2023)
Bill and Melinda Gates Foundation Award to attend Grand Challenges Annual Meeting in Dakar, Senegal (2023)
Fellow of the West Bengal Academy of Science & Technology (2022)
Young Scientist Award from International Life Sciences Institute-India for Improving Public Health in the Areas of Food Safety, Nutrition and Wellbeing (2021)
Bill and Melinda Gates Foundation Award to attend US-Japan Joint Panel Conference on Cholera and Other Bacterial Enteric Infections (2018)
Japan Society for the Promotion of Science (JSPS) Invitational Fellowship Award (2017).
Invited Member of GTFCC in World Health Organization (WHO) (2010-Till)

Young Investigator Award (1^stprize) from Yakult India Microbiota and Probiotic Science Foundation, 2016

Editorial Board Member

Microbial Ecology (Editorial Board Member)

Gut Microbiome (Editorial Board Member)

Frontiers in Microbiology (Guest Associate Editor)

Frontiers in Genetics (Guest Associate Editor)

EC Microbiology (Editorial Board Member)

Best Poster Award in Conference/Symposium

•   Best Poster Award (2018) in Biozest 2018 for research on CTX-phage replication and integration. Organizers: South Asian University, New Delhi on 6th December 2018.
      Title: Deciphering the host bacterial factors essential for integration and replication of CTX-phage
      Presenting author: Archana Pant, Corresponding author: Bhabatosh Das.

•   Best Poster Award (2018) in the international Probiotic Symposium “Probiotics through the Lifespan” for research on the Gut Microbiome and Antimicrobial resistance (24th-25th November 2018). Organizers: NICED, Kolkata; ILDS, Kolkata; Amity University, Kolkata.
     Title: Gut microbiome is the epicenter for dissemination of antimicrobial resistance traits
     Presenting author: Jyoti Verma, Corresponding author: Bhabatosh Das.

•   Best Poster Award (2018) for Antimicrobial resistance research in the international Probiotic Symposium, “ Probiotics through the Lifespan” (24-25 Nov. 2018). Organizers: NICED, Kolkata; ILDS, Kolkata; Amity University, Kolkata.
     Title: Role of gut microbiota in the emergence of colistin resistant enteric pathogens
     Presenting author: Tarosi Senapati, Corresponding author: Bhabatosh Das.

•   Best Poster Award (2018) in the International Symposium on Infectious Diseases (12-14 November) for Antimicrobial resistance research. Organizer: Regional Centre for Biotechnology, Faridabad and Jamia Hamdard, Delhi.
     Title: Insights into the resistance traits of multidrug resistant enteric pathogens isolated from India
     Presenting author: Satyabrata Bag, Corresponding author: Bhabatosh Das.

•   Best Poster Award (2018) in the International Conference on Antiâ€Microbial Resistance (16-17 Feb. 2018) for Antimicrobial resistance research. Organizer: NIPER, Kolkata and NICED Kolkata.
     Title: Molecular insights into antimicrobial resistance traits of multi drug resistant commensal human gut microbiota
     Presenting author: Satyabrata Bag, Corresponding author: Bhabatosh Das.

•   Best Poster Award (2018) in the NIPGR and THSTI Open day (28th September) for Antimicrobial resistance research.
     Title: Antibiotic resistance in commensal and pathogenic bacteria
     Presenting author: Jyoti Verma, Corresponding author: Bhabatosh Das.

•   Best Poster Award (2017) in “Cardiovascular Research Convergence” conference on 12th and 19th August 2017 for Human Microbiome research . Organizers: AIIMS-Delhi and THSTI-Faridabad.
     Title: Gut Microbiome in Inflammatory Bowel Disease: A Comparative analysis in the Indian population
     Presenting author: Tarini Shankar Ghosh. Corresponding author: Bhabatosh Das

•   Best Poster Award (2017) in “THSTI foundation day for Human Microbiome research. Organizer: THSTI.
     Title: Insights into the Gut Microbiome of Inflammatory Bowel Disease patients living in different parts of India
     Presenting author: Tarini Shankar Ghosh. Corresponding author: Bhabatosh Das.

Invited Speaker: (2024) DBT-ICMR-IAVI jointly organized workshop on Novel intervention approaches to combat “Anti-Microbial Resistance” on 3rd May 2024 at India Habitat Center, New Delhi.
Title: Genomics of drug-resistant Indian priority pathogens of clinical and environmental origins

          Invited Speaker: (2024) Genomics Analysis and Technology Conference (GATC) 2024 organized by ICGEB, New Delhi India, from April 12-14, 2024.
          Title: Distinct genomic signatures of extensively drug-resistant Indian priority pathogens of clinical and environmental origins

          Invited Speaker: (2024) Workshop on Recent Advancement in Next Generation Sequencing and Data Analysis organized by the Dept. of Biotechnology, NIPER Guwahati on 10th April 2024.
          Title: Chemistry, Technology, and Applications of Next-Generation Sequencing

          Invited Speaker: (2024) Young Pharmacologist Conclave for Fostering Research and Innovations” during the 9th and 10th April 2024 at Royal Global University, Guwahati.
          Title: Metagenomics and Microbial Genome Engineering for Biotherapeutics Discovery

          Invited Speaker: (2024) National Conference on AMR “Exploring the Bioresources of India to fight against Antimicrobial Resistance (AMR)” organized by ICMR-NICED, DBT-IBSD in association with Society of Ethnopharmacology (SFE), on 4-5 April, 2024 at Kolkata.
         Title: Microbial genome decoding and genome engineering for novel antibiotic potentiators discovery

         Invited Speaker: (2024) National Seminar on “Recent Advances in Animal Science” organized by the Visva-Bharati, Santiniketan on March 07-08, 2024
       Title: Genomics and Genome Engineering for Drug Discovery: A New Era in Therapeutics

       Invited Speaker: (2024) Conference on Microbial Ecology: Interactions and Evolution" to celebrate 40th Foundation Day of CSIR-IMTECH on January 20th 2024.
         Title: Exploring the functions of Human Microbiome as Potential Source of Biotherapeutics

         Invited Speaker: (2024) Faculty Development Program on “Fundamentals and Applications of Genomics”, Department of Biotechnology, Manav Rachna International Institute of Research & Studies, Faridabad on 13th Jan 2024
         Title: Next-Generation Sequencing: Chemistry, Technology, and applications in clinical and fundamental sciences

         Plenary Lecture: (2023) International conclave on AMR and the future of antibiotics from 8th - 9th November 2023 organized by the SRM University, Andhra Pradesh.
         Title: Functional and Genetic Heterogeneity of Antimicrobial Resistance Among Multidrug-Resistant Gram-negative Pathogens

         Keynote Speaker: (2023) Indo-US International Conference & Workshop on Antimicrobial Resistance and Human Microbiome jointly organized by the National Institute of Allergy and Infectious Diseases (NIAID) and THSTI, Faridabad from

         November 15–18, 2023.
         Title: Genomic Insights into AMR Heterogeneity of Bacterial Pathogens for Drug Discovery

         Guest Speaker: (2023) International Conference on Integrated Proteomics: Applications in Food, Nutrition and Health organized by the Proteomics Society at NIPGR- Delhi, India from November 20–22, 2023.

Title: Integrated genomic and proteomic analyses of XDR critical priority bacterial pathogens

         Invited Speaker: (2023) Seminar on emerging Antimicrobial resistance in Human pathogens organized by the Institute for Integrative Biology of the Cell, France on 12th October 2023
         Title: Microbial genomics for drug discovery and development

         Guest Speaker: (2023) USAID RISE National Workshop on Next-Generation Sequencing: Exploring the Genomic Frontier" held at The Grand, Delhi on July 13-14, 2023
         Title: Whole Genome Sequencing of drug-resistant bacterial pathogens

        Guest Speaker: (2023) "Symposium on The Role of Probiotics in Neonatal and Child Health" under the aegis of the Probiotic Association of India in early April 2023, RLAC, Delhi University
         Title: Probiotics: Current understanding and future prospects

         Guest Speaker: (2023) Hands-on workshop on "Next Generation Sequencing and Data Analysis" from February 15–17, 2023 at THSTI, Faridabad  â€¨
         Title: NGS: Advances and Applications

         Guest Speaker: (2023) DNA sequencing workshop at JIPMER Academic Centre, JIPMER Pondicherry on 9th March 2023.
         Title: Overview of Bioinformatics workflow, Raw files, genomic alignment, annotation

       Guest Speaker: (2023) AMR 2023 week invited talk from The Army College of Medical Sciences, New Delhi 22nd of November 2023
         Title: Genomic Insights into AMR Heterogeneity for the Discovery and Development of Therapeutics

         Guest Speaker: (2023) International Conference on Translational Research organized by the All India Institute of Medical Sciences, New Delhi from 16th – 18th October 2023
         Title: Genetic heterogeneity of antimicrobial resistance among multidrug-resistant Gram-negative pathogens

         Guest Speaker: (2023) Winter school lecture at Animal Biotechnology Centre, National Dairy Research Institute Karnal on Mar 4, 2023.
         Title: Rapid Detection of Antimicrobial Resistance Genes in Clinical Isolates by Dipstick Methods

         Guest Speaker: (2023) National meeting on Antimicrobial Resistance: Genomic surveillance on February 24, 2023 at Indian Council of Medical Research, Delhi.
         Title: WGS based analysis of different MDR bacterial isolates (2016-2022) from five different hospitals located across India

        Guest Speaker: (2023) International meeting on “An interdisciplinary approach to biological science” organized by the IACS, Kolkata, India between 1-3rd of February 2023
        Title: Genome plasticity and antimicrobial resistance in bacterial pathogens

        Invited Speaker: (2023) Invited talk on Antimicrobial resistance in bacterial pathogens at Rajiv Gandhi Centre for Biotechnology (RGCB), Thiruvananthapuram on 27 January 2023
Title: Genetic Heterogeneity and Dynamics of Antibiotic Resistance Genes in Bacterial Pathogens

       Keynote Speaker: (2023) National Conference on “Opportunities for MSME’s from Drug Discovery to Development ” from 10th-14th January 2023 organised by the Delhi Pharmaceutical Sciences and Research University
       Title: Translating Next Generation DNA Sequencing into Clinical Research: Opportunities and Challenges

Guest Speaker: (2022) 91st Annual Meeting of the Society of Biological Chemists (India) organized by The Society of Biological Chemists (I) Kolkata Chapter and Sister Nivedita University, Kolkata

Title: Antibiotic Resistance in Gram-negative Human Pathogens: Genetic Heterogeneity and Dynamics

Guest Speaker: (2022) 6th Biennial PAi Conference and Int'l Symposium on Psychobiotics and Gut: Potential in Neurological Disorders, organized by the ICAR-National Dairy Research Institute, Karnal and Probiotic Association of India on 5 - 6 December 2022.

Title: Genome Editing for Next-Gen Probiotics

Guest Speaker: (2022) 16^th Asian Conference on Diarrhoeal Disease and Nutrition (ASCODD-2022) organized by the National Institute of Cholera and Enteric Diseases (NICED) on 11^th – 13^th

November 2022 at Kolkata

Title: Next generation sequencing technologies: Advances and applications in research and diagnostics

Guest Speaker: (2022) Annual meeting organized by the International Life Sciences Institute India on 12^th October 2022 at New Delhi

Title: Human microbiome in health and disease

Guest Speaker: (2022) International conference on A Gateway to Understand Complex Pancreatic Disorders organized by the Indian Pancreatic Club on 8^th – 9^th October 2022 at New Delhi

Title: Basic of Human microbiome

Guest Speaker: (2022) 16^th Asian Conference on Diarrhoeal Disease and Nutrition (ASCODD-2022) organized by the National Institute of Cholera and Enteric Diseases (NICED) on 11^th – 13^th

November 2022 at Kolkata

Title: Homeostasis and Dysbiosis of human microbiome in health and disease

Guest Speaker: (2022) One-day symposium on Inflammation Organized by the Translational Health Science and Technology Institute on 14^th July 2022

Title: Inflammation and microbiome

Guest Speaker: (2022) The Vaginal Microbiome Research Consortium 2022 annual meeting organized by the Bill and Melinda Gates Foundation on 7^th January 2022

Title: Vaginal microbial signature in birth outcomes in the GARBH-Ini pregnancy cohort

Guest Speaker: (2022) Seminar on Antimicrobial Resistance organized by the Ruhvenile Biomedical Pvt. Ltd. Delhi on 23^rd April 2022

Title: Antibiotic potentiator: A key to unlock antibiotic resistance

Guest Speaker: (2022) One-day Symposium on Metabolic Associated Fatty Liver Disease Organized by the Translational Health Science and Technology Institute on 25 May 2022

Title: Geo-Specific Signature of Gut Microbiome Associated with NAFLD

Guest Speaker: (2022) Science Setu Talk organized by the Translational Health Science and Technology Institute.

Title: Micro-organisms that live in and on the human body

Guest Speaker: (2021) Grand challenges Annual Meeting 2021 at Boston, USA organized by the Bill and Melinda Gates Foundation on 8-11 November 2021

Title: Reproductive tract microbiome in Indian women associated with preterm birth

Guest Speaker (Webinar talk 2021): 10^th National Conference (AOGIN) on infections and neoplasia organized by the AIIMS-New Delhi

Title: Dysbiosis of reproductive tract microbiota in Preterm birth

Guest Speaker (Webinar talk 2021): Organized by the Calcutta University on 1st March 2021.

Title: Genetic nature and dynamics of antibiotic resistance traits in the commensal and pathogenic enteric bacteria

Guest Speaker (Webinar talk 2021): Organized by the Amrtita Vishwa Vidyapeetham on 26 February 2021.

Title: Genomics of Extensively Drug Resistant Enteric Bacterial Pathogens Isolated from India

Guest Speaker (Webinar talk 2021): Organized by the Savitribai Phule Pune University, Pune on 2nd February 2021

Title: Understanding role of human gut microbiome in the emergence and spread of antibiotic resistant enteric bacterial pathogens

Guest Speaker (2020, webinar talk) organised by the Dept. of Gastroenterology, AIIMS New Delhi on 18^th August 2020

Title: Homeostasis and Dysbiosis of the Human Gut Microbiome in Health and Diseases

Guest Speaker (2020, webinar talk) organised by the School of Biotechnology, Presidency University, Kolkata on 6-7 August 2020

Title: Human Microbiome in Health and Diseases

Guest Speaker (2020, webinar talk) organised by the Dept. of Science and Technology (DST), Govt. of Rajasthan on 12th April 2020

Title: Human Microbiome in Health and Diseases

Guest Speaker (2020, webinar talk) organised by the Sidho-Kanho-Birsha-University, WB on 8^th June 2020

Title: Molecular insights into COVID-19 and its pathogen SARS-CoV-2

Guest Speaker (2020, webinar talk) organised by the Adamas University, Kolkata on 6^th July 2020.

Title: Gut Microbiome: Associations, Functions and Implications for therapeutics

Guest Speaker (2020): 10^th India probiotic symposium on “Cutting edge science and applications: Intestinal microbiota and Probiotics” organized by the Probiotic Science Foundation on 29^th

February-1^st March 2020 at The Suryaa, New Delhi.

Title: Diet and the Gut Microbiome: Applications, Functions and Implications for Therapeutics.

Keynote Speaker (2019): Seminar on "Current Challenges of antimicrobial Resistance and Potential Intervention by Bacteriophages" organized by the ICMR-NICED on 16th and 17th September at

Hyatt Regency Kolkata.

Title: Insights into Antimicrobial Resistance in Human Associated Microbes.

Guest Speaker (2019): International India|EMBO Symposium on Human Microbiome organized by J. Craig Venter Institute, US and National Institute of Biomedical Genomics, IN on 9-12 Nov, 2019.

Title: Role of vaginal microbiome in preterm birth

Guest Speaker (2019): National seminar on Next Generation DNA sequencing organized by the Pondicherry University, India on 12-13 Dec, 2019.

Title: Next Generation Sequencing Technology and Application.

Guest Speaker (2019): National Institute of Pharmaceutical Education and Research (NIPER) Kolkata on 7th November 2019.

Title: Insights into antibiotic resistance in human associated gut microbiota

Guest Speaker (2019): Frontiers in Biological Sciences. Organizers: (i) St. Xavier's College, (ii) Presidency University (iii) CSIR-IICB, Kolkata.

Title: Understanding the role of human gut microbiome in the emergence of antibiotic resistant enteric bacterial pathogens

Guest Speaker (2019): Workshop on Translational Health at The International Centre for Genetic Engineering and Biotechnology (ICGEB), New Delhi on 11^th - 15^th March 2019.

Title: Structure, functions and dynamics of gut microbiome of Indian population living in rural and urban areas.

Guest Speaker (2019): All India Institute of Medical Sciences (AIIMS), New Delhi (2^nd March. 2019)

Title: Metagenomics

Guest Speaker (2019): All India Institute of Medical Sciences (AIIMS), New Delhi (23^rd Feb. 2019)

Title: Human Microbiome: Concept, Approaches and Implications

Guest Speaker International Conference on “Role of Probiotics in Promoting Healthy Microbiome for Health and Immunity” organized by International Life Science Institute- India, New Delhi on 6^thDecember 2018.

Title: Impact of Microbial Community DNA Extraction Method on Human Microbiome Study

Guest Speaker 9^th India Probiotic Symposium organized by the Gut Microbiota and Probiotic Science Foundation in association with Amity University, Kolkata, National Institute of Cholera and Enteric Diseases (NICED), Kolkata and the Indian Institute of Liver and Digestive Sciences, Kolkata on 24^th- 25^th November 2018.

Title: Gut Microbiome of Healthy Indian Population Living in Urban and Rural Areas

Guest Speaker International Conference on Microbiome Research (ICMR) 2018, National Centre For Cell Science, Pune on 19^th - 22^nd November 2018.

Title: Gut Microbiome of Indian Population in Health and Diseases

Guest Speaker Institute of Life Sciences, Bhubaneswar 4^th September 2018.

Title: Gut Microbiome of Indian Population in Health and Diseases

Guest Speaker Workshop and seminar on Translational research in biomedical and agricultural sciences, All India Institute of Medical Sciences, New Delhi, 6^th – 7^th July 2018.

Title: Molecular Insights into Antimicrobial Resistance Traits of Human Gut Microbiota

Guest Speaker Manipal Academy of Higher Education, Manipal 14^th March 2018

Title: Current Understanding of the Human Microbiome

Guest Speaker Current trends in Genomics at Aligarh Muslim University, Aligarh on 21 March 2018.

Title: Genomics of commensal and pathogenic enteric bacteria: AMR perspectives

Guest Speaker NASH-context and Research at Indian Institute of liver and digestive Sciences, Kolkata on 6^th February 2018.

Title: Microbiome and Metabolic Diseases

Guest Speaker Graduate School of Medicine, Osaka University, Japan on 27^th October 2017.

Title: Insights into Gut Microbiome of Indian Population in Health and Diseases

(1) Nutra Ingradients USA (24 September 2018)

Title: Microbiome insights

https://www.nutraingredients-usa.com/Article/2018/09/24/NutraIngredients-USA-Global-Round-up-Increasing-B2-production-Amway-in-India-and-more

(2) The Hindu (26^th August 2018)

Title: A nursery of drug resistance

https://www.thehindu.com/sci-tech/health/a-nursery-of-drug-resistance/article24782373.ece

(3) BusinessLines (21st August 2018)

Gut bacteria are a reservoir of drug resistance genes: study

https://www.thehindubusinessline.com/news/science/gut-bacteria-are-a-reservoir-of-drug-resistance-genes-study/article24744954.ece

(4) Nature India(29 July 2018)

Pathogens pick up drug resistance genes from friendly bacteria

https://www.natureasia.com/en/nindia/article/10.1038/nindia.2018.95

(5) Nature India (July11, 2018)

Rural Indians have healthier guts than urban folks

https://www.natureasia.com/en/nindia/article/10.1038/nindia.2018.88

(6) Dept. of Biotechnology, Govt. of India (July 23, 2018)

Richness, functions and diversity of the gut microbiome of healthy Indians

http://www.dbtindia.nic.in/gut-microbiome-of-healthy-indians/

(7) Vigyan Prasar, Dept. of Science and Technology, Govt. of India (July 19, 2018)

A peek into gut of Indians throws up surprises

http://vigyanprasar.gov.in/isw/peek_into_gut_indians_throwsup_surprises_story.html

(8) The Hindu (July 22, 2018)

What your gut is telling you

https://www.thehindu.com/sci-tech/health/what-your-gut-is-telling-you/article24485083.ece

(9) Hindustan Times (July 22, 2018)

Vegetarian diet helps keep Indian gut healthy: Study

https://www.hindustantimes.com/health/vegetarian-diet-helps-keep-indian-gut-healthy-study/story-9fEx1ypTnvOlm1y9zoJKzL.html

(10) Deccan Herald (23rd July, 2018)

Scientists map gut microbiota of Indians

https://www.deccanherald.com/national/scientists-map-gut-microbiota-682983.html

(11) The Hindu (15th October 2017)

We need to talk about AMR

https://www.thehindu.com/todays-paper/tp-opinion/we-need-to-talk-about-amr/article19864066.ece

(12) Fountain ink (17th May 2017)

The body’s secret garden: How the exploration of the microbiome is going to change face of medicine

https://fountainink.in/reportage/the-body039s-secret-garden

(13) Dept. of Biotechnology, Govt. of India (2015)

Scientists in THSTI Develop Novel Genetic Tools to speed up Drug Discovery Research

http://www.dbtindia.nic.in/scientists-in-thsti-develop-novel-genetic-tools-to-speed-up-drug-discovery-research/

(14) Times of India (Aug 17, 2015)

Research roundup: Vector-wise

https://timesofindia.indiatimes.com/home/education/news/Researcg-roundup-Vector-wise/articleshow/48511390.cms

(14) Times of India (Aug 17, 2015)

Research roundup: Vector-wise

https://timesofindia.indiatimes.com/home/education/news/Researcg-roundup-Vector-wise/articleshow/48511390.cms

DR.PRADIPTA JANA
SENIOR TECHNICAL OFFICER

MS.SHASHI KUMARI
PH.D STUDENT

MS.MEENAL CHAWLA
PH.D STUDENT

MS.TANSHI MEHROTRA
PH.D STUDENT

MS.BHARTI
PH.D STUDENT

MR.ROSHAN KUMAR
LAB TECHNICIAN

MS.SHRUTI LAL
PROJECT ASSOCIATE-I

MS.SHREYA SARKAR
PROJECT ASSOCIATE-I

MS.KAJAL KAMBOJ
PH.D STUDENT

DR.MAHENDRA DEVIDAS JAMDHADE
TECHNICAL OFFICER-I

DR.DAIZEE TALUKDAR
RESEARCH SCIENTIST

MS.PRIYANKA VERMA
PH.D STUDENT

DR.SACHIN HARLE
RESEARCH SCIENTIST

MS.SHALINI KUMARI
LAB TECHNICIAN

MS.NISHA
TECHNICAL ASSISTANT

DR.UPMA SINGH
RESEARCH ASSOCIATE-I

MS.KAPUGANTI RAMANI SHYAM
SENIOR PROJECT ASSOCIATE

MS.SUSMITA BAKSHI
SENIOR PROJECT ASSOCIATE

MS.JYOTI SINGH
LAB TECHNICIAN

MS.NISHTHA BHARDWAJ
PROJECT ASSOCIATE-I

DR.PRABHAKAR BABELE
RESEARCH SCIENTIST

MR.SANBARTA GANGULY
TECHNICAL ASSISTANT

MS.VAISHALI GUPTA
PROJECT RESEARCH SCIENTIST-I

MS.PREETI
LAB TECHNICIAN

DR.DEEPJYOTI PAUL
RESEARCH SCIENTIST

BHABATOSH[AT]THSTI[DOT]RES[DOT]IN