• भारत सरकार के विज्ञान एवम प्रौदयोगिकी मंत्रालय के जैव प्रौदयोगिकी विभाग की स्वायत्त संस्थान
  • AN AUTONOMOUS INSTITUTE OF DEPT. OF BIOTECHNOLOGY, MINISTRY OF SCIENCE AND TECHNOLOGY, GOVT OF INDIA
  • होम
  • संकाय प्रोफ़ाइल
Publication

From Ph.D. Thesis:

1.Sundaramoorthy N.S, Sivasubramanian A, Nagarajan S. Simultaneous inhibition of MarR by salicylate and efflux pumps by curcumin sensitizes colistin resistant clinical isolates of Enterobacteriaceae. Microb Pathog, 2020; 148: 104445 

2. Sundaramoorthy N.S, Mohan H.M, Subramanian S, Raman T, Ganesan S.S, Sivasubramanian A, Nagarajan S. Ursolic acid inhibits efflux and curtails colistin resistant Enterobacteriaceae. AMB Expr, 2019; 9:27 

3. Sundaramoorthy N.S, Suresh P, Ganesan S.S, GaneshPrasasd A, Nagarajan S. Restoring colistin sensitivity in colistin-resistant E. coli: Combinatorial use of MarR inhibitor with efflux pump inhibitor. Sci Rep, 2019; 9:19845 

4. Bharathan S, Sundaramoorthy N.S, Chandrasekaran H, Rangappa G, ArunKumar G.P, Subramaniyan S.B, Veerappan A, Nagarajan S. Sub lethal levels of platinum nanoparticle cures plasmid in combination with carbapenem, curtails carbapenem resistant Escherichia coli. Sci Rep, 2019; 9:5305 

Review:

 

1.      Sundaramoorthy N.S,Shankaran P, Gopalan V, Nagarajan S. New tools to mitigate drug resistance in Enterobacteriaceae – Escherichia coli and Klebsiella pneumoniae. Crit. Rev. Microbiol., 2022.

Other Publications:

5. Sundaramoorthy N.S, Thothathri S, Bhaskaran M, GaneshPrasad A, Nagarajan S. Phages from Ganges River curtail in vitro biofilms and planktonic growth of drug resistant Klebsiella pneumoniae in a zebrafish infection model. AMB Expr, 2021; 11(1): 27

6. Sundaramoorthy N.S, Mitra K, Ganesh J.S, Makala H, Lotha R, Bhanuvalli S.R, Ulaganathan V, Tiru V, Sivasubramanian A, Nagarajan S. Ferulic acid derivative inhibits NorA efflux and in combination with ciprofloxacin curtails growth of MRSA in vitro and in vivo. Microb Pathog, 2018; 54-62 

7. Lowrence R.C, Ramakrishnan A, Sundaramoorthy N. S, Shyam A, Mohan, V, Subbarao H.M.V, Ulaganathan V, Raman T, Solomon A, Nagarajan S. Norfloxacin salts of carboxylic acids curtail planktonic and biofilm mode of growth in ESKAPE pathogens. J Appl Microbiol, 2018; 124: 408-422 

8. Lotha R, Shamprasad B.R, Sundaramoorthy N.S, Nagarajan S, Sivasubramanian A. Biogenic phytochemicals (cassinopin and isoquercetin) capped copper nanoparticles (ISQ/CAS@CuNPs) inhibits MRSA biofilms. Microb Pathog, 2019; 132:178-187. 

9. Lotha R, Shamprasad B.R, Sundaramoorthy N.S, Ganapathy R, Nagarajan S, Sivasubramanian A. Zero valent silver nanoparticles capped with capsaicinoids containing Capsicum annuum extract, exert potent anti-biofilm effect on food borne pathogen Staphylococcus aureus and curtail planktonic growth on a zebrafish infection model. Microb Pathog, 2018; 124:291-300 

10. Lotha R, Sundaramoorthy N.S, Shamprasad B.R , Nagarajan S, Sivasubramanian A. Plant nutraceuticals (Quercetrin and Afzelin) capped silver nanoparticles exert potent antibiofilm effect against food borne pathogen Salmonella enterica serovar Typhi and curtail planktonic growth in zebrafish infection model. Microb Pathog, 2018; 120: 109-118 

 

11. Manigandan A, Handi V, Sundaramoorthy N.S, Dhandapani R, Radhakrishnan R, Sethuraman S, Subramanian A. Responsive Nanomicellar Theranostic Cages for Metastatic Breast Cancer, Bioconjugate Chem (2018)

  1. Sundaramoorthy N.Sand Nagarajan S.  Can Nanoparticles help in the battle against drug resistant infections in “Post – Antibiotic Era”? AMR – Underlying mechanisms and therapeutic approaches. Springer Nature, 2022; 175 - 213
  2. Sundaramoorthy N.S, Raman T and Nagarajan S. Zebrafish as an Indispensable Tool for Infectious Diseases and Immune Modulatory Studies. Zebrafish Model for Biomedical Research. Springer Nature, 2022; 181-195
  3. Sri N.S,Thiagarajan R, Manikandan R, Arumugam M. Curcumin based food supplements: Challenges and future prospects. Non vitamin and non-mineral Nutritional supplements. Academic Press. 2019:119-128
  4. Lalitha C, Rathore S.S, Raman T, Sundaramoorthy N.S, Ramakrishnan J. Do non-medical uses of antibiotics develop cross resistance in clinical pathogens? Bacterial Adaptation to Co-resistance OR Agricides to Antibiotics: Bacterial Tolerance. Springer Nature, 2019; 81-107
  5. Sri N.S,Thiagarajan R, Manikandan R, Arumugam M. Curcumin and molecular targets on eye diseases. Studies in Natural Products Chemistry. Elsevier. 2019; 63: 339-356

1. Identification of enhancers of known TB drugs by performing phenotypic or macrophage based screens. (MK Bhan Young Research Fellowship 2023-2026 Ongoing)

2. Reversing colistin resistance in MDR E. coli by combinatorial approach: Use of MarR inhibitor in coniunction with efflux pump inhibitor (CSIR SRF fellowship 2021-2022)

  • MK Bhan Young Research Fellowship from Department of Biotechnology (DBT), India (2023)
  • Senior Research Fellow from Council of Scientific & Industrial Research (CSIR), India (2021)
  • Best oral presentation in 3rd Annual National meet (2019) of Centre for Research on Infectious diseases (CRID), SASTRA deemed University, Thanjavur guested by Prof. Tapas K. Kundu, Director, CSIR-CDRI, Lucknow, India (Title of the talk: Role of sub lethal levels of Platinum nanoparticles as a plasmid curing agent to reverse drug resistance in MDR E. coli)
  • Best short talk in 2nd Annual national meet (2018) of Centre for Research on Infectious diseases (CRID), SASTRA deemed University, Thanjavur (Title of the talk: Comparison of Bacteriophage(s) from Ganges and Cauvery River to Curtail Gram Negative Pathogens In Planktonic & Biofilm Mode of Growth In-vitro & In-vivo)

Mentor: Dr. Ramandeep Singh, Professor, THSTI

  • NIRANJANASRI[AT]THSTI[DOT]RES[DOT]IN