- Post Doctoral Fellow, THSTI
- Ph.D. Biochemistry, Jiwaji University
- M.Sc. Biochemistry, Pune University
Broad area of research
2. Mass spectrometry
3. Biomarker discovery
4. Anti-microbial resistance
Babele P, Midha M, Rao K, Kumar A. Temporal Profiling of Host Proteome against Different M. tuberculosis Strains Reveals Delayed Epigenetic Orchestration. Microorganisms (2023).
Babele P, Yadav AK. Back2Basics: mass-to-charge ratio (m/z) in proteomics. J Proteins Proteom. (2023). https://doi.org/10.1007/s42485-023-00115-7.
Mehrotra T, Konar D, Pragasam AK, Kumar S, Jana P, Babele P, Paul D, Purohit A, Tanwar S, Bakshi S, Das S, Verma J, Talukdar D, Narendrakumar L, Kothidar A, Karmakar SP, Chaudhuri S, Pal S, Jain K, Srikanth CV, Sankar MJ, Atmakuri K, Agarwal R, Gaind R, Ballal M, Kammili N, Bhadra RK, Ramamurthy T, Nair GB, Das B. Antimicrobial resistance heterogeneity among multidrug-resistant Gram-negative pathogens: Phenotypic, genotypic, and proteomic analysis. Proc Natl Acad Sci U S A (2023). 120(33):e2305465120. doi: 10.1073/pnas.2305465120. Epub 2023 Aug 7. PMID: 37549252.
Rizvi ZA, Babele P, Madan U, Sadhu S, Tripathy MR, Goswami S, Mani S, Dikshit M, Awasthi A. Pharmacological potential of Withania somnifera (L.) Dunal and Tinospora cordifolia (Willd.) Miers on the experimental models of COVID-19, T cell differentiation, and neutrophil functions. Front Immunol. (2023). 14:1138215. doi: 10.3389/fimmu.2023.1138215. PMID: 36960064; PMCID: PMC10028191.
Babele P, Rizvi ZA, Sadhu S, Madan U, Tripathy MR, Goswami S, Mani S, Kumar S, Awasthi A, Dikshit M. Prophylactic treatment of Glycyrrhiza glabra mitigates COVID-19 pathology through inhibition of pro-inflammatory cytokines in the hamster model and NETosis. Front Immunol. (2022). 13:945583. doi: 10.3389/fimmu.2022.945583. PMID: 36238303; PMCID: PMC9550929.
Sabna S, Kamboj DV, Kumar RB, Babele P, Rajoria S, Gupta MK, Alam SI. Strategy for the Enrichment of Protein Biomarkers from Diverse Bacterial Select Agents. Protein Pept Lett. (2021). 28(9):1071-1082. doi: 10.2174/0929866528666210405160131. PMID: 33820508.
Sabna S, Kamboj DV, Rajoria S, Kumar RB, Babele P, Goel AK, Tuteja U, Gupta MK, Alam SI. Protein biomarker elucidation for the verification of biological agents in the taxonomic group of Gammaproteobacteria using tandem mass spectrometry. World J Microbiol Biotechnol. (2021). 37(5):74. doi: 10.1007/s11274-021-03039-w. PMID: 33779874.
Babele P, Kumar RB, Rajoria S, Rashid F, Malakar D, Bhagyawant SS, Kamboj DV, Alam SI. Putative serum protein biomarkers for epsilon toxin exposure in mouse model using LC-MS/MS analysis. Anaerobe (2020). 63:102209. doi: 10.1016/j.anaerobe.2020.102209. Epub 2020 May 6. PMID: 32387808.
Rajoria S, Sabna S, Babele P, Kumar RB, Kamboj DV, Kumar S, Alam SI. Elucidation of protein biomarkers for verification of selected biological warfare agents using tandem mass spectrometry. Sci Rep. (2020). 10(1):2205. doi: 10.1038/s41598-020-59156-3. PMID: 32042063; PMCID: PMC7010682.
Babele P, Verma S, Kumar RB, Bhagyawant SS, Kamboj DV, Alam SI. Elucidation of protein biomarkers in plasma and urine for epsilon toxin exposure in mouse model. Anaerobe (2019). 59:76-91. doi: 10.1016/j.anaerobe.2019.05.010. Epub 2019 May 27. PMID: 31145997.
Babele P, Mishra A. A comparative study of antibacterial activity of crude extracts preparations of five medicinal plants: Ocimum sanctum, Ajadirachta indica, Punica granatum, Psidium guajava, and Syzygium aromaticum against multi drug resistant bacteria of clinical origin. World J Pharm Res. (2014). Vol.3 No.5 Suppl. pp.1174-1187 ref.31
Understanding the genomic repertoires and proteomes of extensively drug-resistant Serratia marcescens isolated from rural India
A pilot study on the large-scale analysis of chronic pancreatitis through high-throughput mass spectrometry-based proteomics and proteogenomics for biomarker discovery
Young scientist award at 34th M.P. Young Scientist Congress (MPCST)
Oral presentation award in Young Scientist Conference at 6th India International Science Festival (IISF)
CSIR-NET JRF with All India Rank 59/832
Madhya Pradesh State Eligibility Test (MP-SET)
GATE-BT with All India Rank 149/10719
Organized post-conference workshop on "Biomedical Proteomics and Data Analysis" during 15th Annual meeting of Proteomic Society, New Delhi, November 23, 2023
Organized two-day workshop on "Proteomics and Data Analysis" in THSTI under the aegis of Proteomic Society, Faridabad, February 09-10, 2023
Invited talk on "Proteomics Application in Medicine" in one-day National Symposium organised by Barkatullah University, Bhopal, February 03, 2023
Ms. Nivedita Som
Mr. Ravi Maddeshiya