• भारत सरकार के विज्ञान एवम प्रौदयोगिकी मंत्रालय के जैव प्रौदयोगिकी विभाग की स्वायत्त संस्थान
  • AN AUTONOMOUS INSTITUTE OF DEPT. OF BIOTECHNOLOGY, MINISTRY OF SCIENCE AND TECHNOLOGY, GOVT OF INDIA
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  • संकाय प्रोफ़ाइल
Publication

 

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2024

  • Anurag Raj, Suruchi Aggarwal, Prateek Singh, Amit Kumar Yadav*, Debasis Dash*. PgxSAVy: a tool for comprehensive evaluation of variant peptide quality in proteogenomics–catching the (un) usual suspects.Computational and Structural Biotechnology Journal, 2024. doi: 10.1016/j.csbj.2023.12.033.

2023

2022

2021

2020

2019

 

2018

 

2017

 

2016

 

2014

 

2013

 

2012

 

2011

  • Inventors - Ajay Kumar, Shilpa Jamwal, Suruchi Aggarwal, Kanury VS Rao, Amit Kumar YadavMethod of hyperplexing in mass spectrometry to elucidate temporal dynamics of proteome (provisional patent filed)

  • Inventors - Ajay Kumar, Shilpa Jamwal, Suruchi Aggarwal, Kanury VS Rao, Amit Kumar YadavMethod of hyperplexing in mass spectrometry to elucidate temporal dynamics of proteome (PCT filed)

Extramural Projects

  1. To create a proteogenomic reference map of human liver by integrating genomics and proteomic data to facilitate studies on non-alcoholic fatty liver disease (NAFLD) [part of DBT-National Network Project (NNP) with IGIB (Coordinator), THSTI, NIPGR, ILS and NEHU as members, each with their own project] (as Principal Investigator from THSTI, 2023-2028)
  2. A Pilot study on the large-scale analysis of chronic pancreatitis through high-throughput mass spectrometry-based proteomics and proteogenomics for biomarker discovery (as Principal-Investigator from THSTI, AIIMS-THSTI collaborative inter-institutional grant, 2023-2025)
  3. Metabolic associated liver disease (MAFLD) in lean and obese: search for disease and progression biomarkers. (as Co-Investigator, SERB-SUPRA grant, 2022-2025)
  4. Identification of stage-specific diagnostic and prognostic biomarker(s) of Non-alcoholic fatty liver disease using the multi-omics approach. (as Co-Investigator, AIIMS-THSTI collaborative inter-institutional grant, 2019-2022)
  5. DBT- BDI Big Data Initiative grant from Department of Biotechnology, titled “Integrating multiple proteomics database search algorithms in a unified framework for time efficient large scale analyses” (as Principal Investigator, Mar 2018-Sep 2021)
  6. Large-scale proteomics analysis of post-translational modifications and their crosstalks in cardiovascular diseases"- under the IYBA - Innovative Young Biotechnologist Award, 2013 Grant (as Principal Investigator, 2014-2018)

Intramural Project (THSTI):

  • Development of an in-silico tool and database for identification of unique peptide(s)/protein(s) among bacterial genomes/proteomes (as Principal Investigator, 2017-2019)
  • Integrative data mining for genome based rapid detection of antibiotic resistance in Gram - negative ESKAPE pathogens (as Principal Investigator, 2021-2023)
  • Understand the genomic repertoires and proteome of extensively drug resistant Serratia marcescens isolated from rural India (as Co-Investigator, 2022-2024)

As Mentor: (1)

  1. MK Bhan Young Research Fellowshipto Dr. Suruchi Aggarwal – “Stage-specific molecular signature identification for non-alcoholic fatty-liver disease using integrative analysis of multi-omics data and artificial intelligence” (2023)
  • Best Presentation (Runner-up), Virtual Podium Asia Pacific on Proteomics, Metabolomics and Lipidomics, VPAP online (2022)
  • Innovative Young Biotechnologist Award (IYBA) 2013
  • Awarded “Innovators Under 35 2013” (TR35) in India by MIT Technology Review, March 2013 
  • Young Scientist Travel Awardfrom DST (Sep 2011)
  • CSIR-JRF, June 2007 (Top 25)
  • GATE qualified, Feb 2007
  • CSIR-JRF, December 2006

 

Software Copyrights

1.     HyperQuant : Diary no. 5027/2016-CO/SW on 26.04.2016. Suruchi Aggarwal, Amit Kumar Yadav.

2.     QuantWizIQ : Diary No. 2190/2016-CO/SW on 22.02.2016. Suruchi Aggarwal, Amit Kumar Yadav.

3.     MODa Pipeline : Diary no. 2186/2016-CO/SW on 22.02.2016. Manu Kandpal, Suruchi Aggarwal, Amit Kumar Yadav.

4.     ModSTDiary no. 13388/2016CO/SW on 22.11.2016. Suruchi Aggarwal, Amit Kumar Yadav.

5.     ProteomeExplorer : Diary No. 1539/2017-CO/SW on 27.01.2017. Puneet Kumar Kadimi, Suruchi Aggarwal, Amit Kumar Yadav.

6.     TheoLib : Diary No. 2302/2019-CO/SW on 12.02.2019. Pallavi Mahajan, Suruchi Aggarwal, Amit Kumar Yadav.

7.     UniPEPtor: Diary No. 2306/2019-CO/SW on 12.01.2019. Amit Kumar Yadav, Pallavi Mahajan, Asmita Bharti.

 

MR.SANCHIT SINGHANIA
PH.D STUDENT

MS.MANSI RANA
PH.D STUDENT

MS.NIKITA
PROJECT ASSOCIATE-I

MS.USHA M.
PROJECT ASSOCIATE-I

Dr. Ritu Sharaya

Sanchit Singhania

Mansi Rana

Usha M

Nikita Dalal

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  • AMIT[DOT]YADAV[AT]THSTI[DOT]RES[DOT]IN