Publication

1. Narendrakumar L, Suryaletha K, Reghunathan D, Prasannakumar M, Thomas S. 2017. Insights into the draft genome sequence of a Haitian variant Vibrio cholerae strain isolated from a clinical setting in Kerala, South India. Genome Announcement 5:e00843-17. doi.org/10.1128/genomeA.00843-17. (IF- NA, ASM Journal)
2. Lekshmi. N^*, Jose D^*, Goel A K, Kumar RA, Thomas S. 2017. Development of a novel herbal combination to inhibit biofilm formation in toxigenic Vibrio cholerae. Journal of Food protection. 1933-1940. doi: 10.4315/0362-028X.JFP-17-091. (IF- 2) (^* Equal first author)
3. Lekshmi N, Joseph I, Ramamurthy T, Thomas S. 2018. Changing facades of Vibrio cholerae: an enigma in the epidemiology of cholera. Indian Journal of Medical Research. 147:  133-141. DOI: 10.4103/ijmr.IJMR_280_17.(IF- 4.2)
4. Narendrakumar L, Thomas S. 2018. Vibrio cholerae O1 gaining reduced susceptibility   to doxycycline, India. Journal of Global Antimicrobial Resistance. 31;12:141-142. doi: 10.1016/j.jgar.2018.01.009. (IF- 4.6)
5. Narendrakumar L, Gupta SS, Johnson JB, Ramamurthy T, Thomas S. 2019.  Molecular adaptations and antibiotic resistance in Vibrio cholerae: a communal challenge. Microbial Drug Resistance. 25(7):1012-1022. http://doi.org/10.1089/mdr.2018.0354. (IF- 2.6)
6. Narendrakumar L, Theresa M, Krishnankutty Chandrika S, Thomas S. 2019.  Tryptanthrin, a potential biofilm inhibitor against toxigenic Vibrio cholerae, modulating the global quorum sensing regulator, LuxO. Biofouling. 35(10):1093-1103 doi: 10.1080/08927014.2019.1696315 . (IF- 2.7)
7. Lekshmi Narendrakumar, Sivakumar Krishnankutty Chandrika, Sabu Thomas. 2020 Adaptive resistance evolution of V. cholerae to doxycycline associated with spontaneous mutation. International Journal of Antimicrobial Agents. 56(3): 106097. https://doi.org/10.1016/j.ijantimicag.2020.106097.(IF- 10.8)
8. Lekshmi Narendrakumar, Vishnu S. Jaikumar, Sivakumar K. Chandrika and Sabu Thomas. 2020. Epidemiological and pathogenic characteristics of Haitian variant V. cholerae circulating in India over a decade (2000-2018). Microbial Pathogenesis.  149: 104538. doi.org/10.1016/j.micpath.2020.104538 (IF- 3.8)
9. Narendrakumar L, Joseph I, Thomas S. 2020. Potential Effectiveness and Adverse Implications of Repurposing Doxycycline in COVID-19 Treatment. Expert Review of Anti-infective Therapy. 24:1-8. doi. 10.1080/14787210.2021.1865803 (IF- 5.7) 
10. Lekshmi Narendrakumar, Anusha Gopinathan, Sreekrishnan TP, Anisha Asokan, Anil Kumar, Gireesh Kumar, Sabu Thomas. 2021. The bane of coastal marine environment: A fatal case of Vibrio vulnificus associated cellulitis and septicaemia. Indian Journal of Medical Microbiology.39(3): 386-388. (IF- 1.6)
11. Narendrakumar L, Sudhagar A, Preena PG,  Nithianantham SR,  Mohandas SP, Swaminathan TR. 2022. Detection of Mycobacterium marinum and multidrug-resistant bacteria in a chronic progressive disease outbreak among Siamese fighting fish (Betta splendens) in India. Biologia. https://doi.org/10.1007/s11756-022-01118-3 (IF-1.5)
12. Lekshmi Narendrakumar*, Medha Chakraborty, Shashi Kumari, Deepjyoti Paul, Bhabatosh Das. 2023. β-Lactam potentiators to re-sensitize resistant pathogens: Discovery, development, clinical use and the way forward. Frontiers in Microbiology. Doi:10.3389/fmicb.2022.1092556 (IF. 5.2) (Corresponding author)

Co-author publications

1. Suryaletha K, Narendrakumar L, John J, Reghunathan D, Prasannakumar M, Thomas S. 2018. Genomic insights into biofilm-forming Enterococcus faecalis SK460 isolated from a chronic diabetic ulcer patient. Genome Announcement 6:e01463-17. https://doi.org/10.1128/genomeA.01463-17. (IF- NA, ASM Journal)
2. Paul M, Narendrakumar L, R Vasanthakumary A, Joseph I, Thomas S. 2019. Genome sequence of a multidrug-resistant Klebsiella pneumoniae ST78 with high colistin resistance isolated from a patient in India. Journal of Global Antimicrobial Resistance 17 (2019) 187–188. https://doi.org/10.1016/j.jgar.2019.04.008. (IF- 4.6)
3. Suryaletha K, Narendrakumar L, John J, Radhakrishnan MP, George S, Thomas S. 2019. Decoding the proteomic changes involved in the biofilm formation of Enterococcus faecalis SK460 to elucidate potential biofilm determinants. BMC Microbiology 19:146. https://doi.org/10.1186/s12866-019-1527-2. (IF- 4.2)
4. Shashindran N, Narendrakumar L, Udayakumaran S, Vijayakumar DM, Thomas S, Kumar A. First report of Vibrio cholerae O9, novel ST520, isolated from a child with bacteraemia-associated sepsis. Indian Journal of Medical Microbiology 2020; 38: 489-91. (IF- 1.6)
5. Aparna Shankar, Devika Jagajeedas, Megha Periyappilly Radhakrishnan, Merin Paul, Lekshmi Narendrakumar, Karthika Suryaletha, Akhila V.S, Sudha B Nair, Sabu Thomas. Elucidation of Health Risks using Metataxonomic and Antibiotic Resistance Profiles of Microbes in Flood Affected Waterbodies, Kerala 2018. 2020. Journal of Flood Risk Management. 2020; e12673. https://doi.org/10.1111/jfr3.12673 (IF- 4.1)
6. Raja Swaminathan Thangaraj, Lekshmi Narendrakumar, Preena Prasannan Geetha,Arun Raja Shanmuganathan, Arathi Dharmaratnam,Sundar Raj Nithianantham. Comprehensive update on inventory of finfish cell lines developed during the last decade (2010–2020).2021. Reviews in Aquaculture. 13(4): 2248-2288 https://doi.org/10.1111/raq.12566 (IF-10.4)
7. Thangaraj Raja Swaminathan, Sundar Raj Nithianantham, Lekshmi Narendrakumar, Tina Kollannoor Johny, Neeraj Sood, Pravata Kumar Pradhan, and Kuldeep Kumar Lal. 2021. Cichlids endemic to India are not susceptible to Tilapia Lake virus infection. Aquaculture. 548(1): 737589. doi.org/10.1016/j.aquaculture.2021.737589 . (IF- 4.5) 
8. Thangaraj Raja Swaminathan, Sundar Raj N, Lekshmi N, Arathi Dharmaratnam, Neeraj Sood, Pravata Kumar Pradhan, Krupesha Sharma S R, Kuldeep Kumar Lal. 2021. Co-infection of Lactococcus garvieae and Tilapia Lake Virus (TiLV) in Nile tilapia, Oreochromis niloticus (Linnaeus, 1758) cultured in India. Diseases of Aquatic Organisms.  147:127-140. doi.org/10.3354/dao03638 (IF- 1.769). 
9. Arathi Dharmaratnam, Arun Sudhagar, Sweta Das, Reshma Rajeev Nair, Sundar Raj Nithianantham, Prasannan Geetha Preena, Narendrakumar Lekshmi, Thangaraj Raja Swaminathan. (2022). Immune gene expression and protective effects in goldfish (Carassius auratus L.) immunized with formalin-inactivated cyprinid herpesvirus-2 (CyHV-2) vaccine. Microbial Pathogenesis. 164: 105452. https://doi.org/10.1016/j.micpath.2022.105452 (IF- 3.8)
10. Gaurav Rathore, Lekshmi.N, T. Raja Swaminathan. 2022. Antimicrobial resistance in aquaculture and fisheries - status and way forward. Indian Journal of Comparative Microbiology Immunology and Infectious Diseases. 43 (1): 58-65. Doi: 10.5958/0974-0147.2022.00008.3
11. Panwar S, Kumari S, Verma J, Bakshi S, Lekshmi N, Paul D, Das B. (2023) Toxin linked mobile genetic elements in major enteric bacterial pathogens. Gut Microbiome. doi.org/10.1017/gmb.2023.2 
12. Jiffy John, Lekshmi Narendrakumar, Shijulal Nelson Sathi. 2023. Hybrid genome assembly and annotation of multi-drug resistant Staphylococcus aureus genotype ST672-SCCmec type IVd(2B). Journal of Global Antimicrobial Resistance. 32:74-77. doi: 10.1016/j.jgar.2022.12.011. IF- (4.6)
13. Mehrotra T., Konar D., Pragasam AK., Kumar S., Jana P., Babele P., Paul D., Purohit A., Tanwar S., Bakshi S., Das S., Verma J., Talukdar D., Narendrakumar L., Kothidar A., Karmakar SP., Chaudhuri S., Pal S., Jain K., Srikanth CV., Sankar JS., Atmakuri K., Agarwal R., Gaind R., Ballal M., Kammili N., Bhadra RK, Ramamurthy T., Nair GB. Das B. 2023. Antimicrobial resistance heterogeneity among multidrug-resistant Gram-negative pathogens: Phenotypic, Genotypic and Proteomic analysis. Proc. Natl. Acad. Sci. USA. 120(33) e2305465120. https://doi.org/10.1073/pnas.2305465120. IF- (11.1)
14. Paul D, Chawla M, Ahrodia T, Narendrakumar L, Das B. 2023. Antibiotic Potentiation as a Promising Strategy to Combat Macrolide Resistance in Bacterial Pathogens. Antibiotics (Basel). 12(12):1715. doi: 10.3390/antibiotics12121715. IF- (4.8)

Book chapters

1. Narendrakumar L, Das B, Paramasivan B, Rasu J, Thomas S. 2018 Quorum Quenching and Biofilm Inhibition: Alternative Imminent Strategies to Control the Disease Cholera. In: Kalia V. (eds) Biotechnological Applications of Quorum Sensing Inhibitors. pp.63-85. Springer, Singapore https://doi.org/10.1007/978-981-10-9026-4_4
2. Das B, Paramasivan B, Rasu J, Narendrakumar L, Thomas S. 2018 Strategies Behind Biosensors for Food and Waterborne Pathogens. In: Kalia V. (eds) Quorum Sensing and its Biotechnological Applications. pp.107-141. Springer, Singapore https://doi.org/10.1007/978-981-13-0848-8
3. Karthika S, Lekshmi N, Akhilandeswarre D, Devika Das J, Aparna Shankar, Sabu Thomas. 2020. Evolving state-of-the-art technologies in Biofilm research: from static to real-time models. In: Sabu Thomas and Divya M Prabhakaran (eds) Emerging Concepts in Bacterial Biofilms: Molecular Mechanisms and Control Strategies. pp 319-369. Cambridge publishing group.UK.
4. Paul M, Mohan V, Narendrakumar L, Joseph I, Thomas S. 2020. Status Quo of Omics Technologies in Analyzing the Genetic Mediators of Antimicrobial Resistance at Sub-MIC Concentrations. In: Thomas S. (ed) Antimicrobial Resistance: Global Challenges and Future Interventions. Springer, Singapore. pp 207-230. DOI: 10.1007/978-981-15-3658-8_10
5. Lekshmi Narendrakumar, Animesh Ray. 2022. Respiratrory tract microbiome and pneumonia. In: Bhabatosh Das and Vijai Singh (eds). Human microbiome in Health and Disease: Part B, Progress in Molecular Biology and Translational Science. Elsevier. Pp 98-124, ISBN: 9780323912105
6. Narendrakumar L, Geetha Preena P, Swaminathan T.R. 2023. Antimicrobial Resistance in Ornamental Fisheries: Causes and Preventive Measures. In: Mothadaka, M.P., Vaiyapuri, M., Rao Badireddy, M., Nagarajrao Ravishankar, C., Bhatia, R., Jena, J. (eds) Handbook on Antimicrobial Resistance. Springer, Singapore. https://doi.org/10.1007/978-981-16-9723-4_9-1
7. Vashist, A., Verma, J., Narendrakumar, L., Das, B. 2023. Molecular Insights into Genomic Islands and Evolution of Vibrio cholerae. In: Mani, I., Singh, V., Alzahrani, K.J., Chu, DT. (eds) Microbial Genomic Islands in Adaptation and Pathogenicity. Springer, Singapore. https://doi.org/10.1007/978-981-19-9342-8_14
8. Deepjyoti Paul, Ashish Kumar Agrahari, Pratichi Singh and Lekshmi Narendrakumar*. 2024. Microbial surfactants in water remediation. In: Divya Bajpai Tripathy and Anjali Gupta (eds). Microbial Surfactants. IOP Publishing. India. https://doi.org/10.1088/978-0-7503-5989-4 

Books edited

1. Associate Editor, Emerging Concepts in Bacterial Biofilms: Molecular Mechanisms and Control Strategies, In: Sabu Thomas and Divya M Prabhakaran (eds), ISBN: 978-1-5275-4261-7. Cambridge Publishing Group.UK. pp.381
2. Associate Editor, Antimicrobial Resistance: Global Challenges and Future Interventions, In: Thomas S. (ed), ISBN: 978-981-15-3658-8. Springer Nature. Singapore. pp.230  
3. Assistant Editor, Human Microbiome- Clinical implications and therapeutic interventions, In: Thomas S. (ed). Springer Nature. Singapore. pp.264

1.     Bhabatosh Das, Lekshmi.N, Meenal Chawla, Deepjyoti Paul: Title: Genetically engineered bacterial reporter strain and a method for preparing the same thereof. Patent application no. 202411035814. Year: 2024. Indian patent

2.     Bhabatosh Das, Deepjyoti Paul, Lekshmi.N: Title: A novel genetic tool for engineering the genome of gram-negative bacteria and a method of preparing the same thereof. Patent application no. 202411056506. Year: 2024. Indian patent

2021-2024: Study of the dynamics of mobile genetic elements in ESKAPE pathogens associated with neonatal sepsis and screening of antibiotic resistance breakers for re-sensitization of MDR pathogens

1. Best oral presentation at 8^th Global Conference on Gender in Aquaculture and Fisheries (GAF8)- Interventions for control of AMR: Harnessing one health knowledge, Cochin, Kerala, India, November 21-22, 2022. 
2. Best poster award (Day 2) at 16^th Asian Conference on Diarroeal Disease and Nutrition (ASCODD-2022), Kolkata, India, November 11-13th, 2022.
3. Travel grant to attend 16^th Asian Conference on Diarroeal Disease and Nutrition (ASCODD-2022), Kolkata, India, November 11-13th, 2022.
4. Received MK BHAN Young Researcher Fellowship (2020-2021)
5. First Prize for Poster presentation at the Amrita BIOCREST 2021-International Symposium on Antimicrobial Resistance (AMR) Man Vs Microbes Race of the Century organized by Amrita School of Biotechnology, Amritapuri, Kerala, India, February 24-26^th, 2021.
6. DST-ITS Travel grant received from DST-SERB to attend 8th Biennial International Conference on the Biology of Vibrios (ICBV) organised by McGill University, Montreal, Quebec, Canada, November 17^th-20^th,2019
7. Second Prize for Poster presentation at the International Conference on Antibiotic Stewardship and Infectious Diseases organized by Amrita Institute of Medical Sciences in Collaboration with World Health Organization (WHO), India and Imperial College of London, held at Crown Plaza, Kochi, Kerala, October 27^th-28^th, 2018. 
8. Wellcome trust travel award to attend Wellcome Genome Campus Advanced Course, Working with pathogen Genomes, Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam, Nov- 12^th-17^th, 2017
9. American Society of Microbiology Travel grant to attend 2^nd International Conference on Infectious Diseases and Nanomedicine (ICIDN-2015), Kathmandu, Nepal. December 15-18^th, 2015.

Invited Talk

1.     Lekshmi Narendrakumar. Antibiotic potentiation as an effective strategy to revive obsolete drugs. National Symposium on Biotechnology for Sustainable Development 2023. Rajiv Gandhi Centre for Biotechnology. April 12^th, 2023.

Conferences attended

1. Lekshmi N and Sabu Thomas. Molecular studies on the Haitian variant ctxB gene and cholera toxin production in Vibrio cholerae O1 outbreak strains isolated from India.   2^nd International Conference on Infectious Diseases and Nanomedicine (ICIDN-2015), Kathmandu, Nepal.  December 15-18^th , 2015. Oral Presentation
2. Lekshmi N and Sabu Thomas. Molecular epidemiology of Vibrio cholerae outbreak strains with Haitian ctxB allele isolated from south India. 14^th Asian Conference on Diarroeal Disease and Nutrition (ASCODD-2017), Crown Plaza, Kochi, India, October 30,31^st- November 1^st, 2017. Oral Presentation
3. Lekshmi N and Sabu Thomas. Pathogenicity Studies of Multidrug Resistant Vibrio cholerae O1 Outbreak Strains Possessing Haitian Variant ctxB Allele Isolated from Kerala. 30^th Kerala Science Congress, Brennen College, Thalassery, Kerala, India,January 28-30^th 2018. Poster Presentation
4. Lekshmi N and Sabu Thomas. Toxigenic Vibrio cholerae O1 gaining reduced susceptibility to Doxycycline, South India. International Conference on Antibiotic Stewardship and Infectious Diseases organized by Amrita Institute of Medical Sciences in Collaboration with World Health Organization (WHO), India and Imperial College of London, Crown Plaza, Kerala October 27^th-28^th, 2018. Poster Presentation (Second Prize)
5. Lekshmi N and Sabu Thomas. Genomic insights into multidrug resistant Haitian variant V. cholerae circulating in India. 8th biennial International Conference on the Biology of Vibrios (ICBV) organised by McGill University, Montreal, Qubec, Canada, November 17^th-20^th,2019. Poster presentation.
6. Lekshmi.N and Sabu Thomas. Resistance progression of Vibrio cholerae to doxycycline and alternative therapies to tackle cholera. Amrita BIOCREST 2021- International Symposium on Antimicrobial Resistance (AMR) Man Vs Microbes Race of the Century organized by Amrita School of Biotechnology, Amritapuri, Kerala, India, February 24-26^th, 2021. Poster presentation (First Prize)
7. Lekshmi.N, Raja Swaminathan T, Arathi D, Sundar Raj N, Tina K. In vitro and in vivo resistance of rohu, Labeo rohita to cyprinid herpesvirus -2 (CyHV-2). World Fisheries Congress, Adelaide, Australia, September 20-24^th, 2021. Presentation on Demand (Virtual)
8.  Lekshmi Narendrakumar, Deepjyoti Paul, Shashi Kumari, Bhabatosh Das*. Identification of a novel b-Lactam potentiator against enteric and UTI pathogens.  16^th Asian Conference on Diarroeal Disease and Nutrition (ASCODD-2022), Kolkata, India, November 11-13th, 2022. (Best Poster, Day 2)
9. Lekshmi N, Bhabatosh Das. Development of a 3 in 1 reporter strain assay for in-vitro high throughput screening of novel antibiotic potentiators to re-sensitize MDR pathogens. 8^th Global Conference on Gender in Aquaculture and Fisheries (GAF8)- Interventions for control of AMR: Harnessing one health knowledge, Cochin, Kerala, India, November 21-22, 2022. (Best Oral presentation)