
DR.BHARTI BHATIA
PhD
PRINCIPAL SCIENTIST-I
- Post Doc Laboratory of Virology NIAID NIH
- Post-Doc Laboratory of Bacteriology NIAID NIH
- PhD National Institute of Immunology New Delhi
- MSc School of Biotechnology JNU
- BSc Kurukshetra University
Broad Research Areas:
- Zoonotic virus surveillance and characterization in high-risk areas using advanced genomic sequencing techniques
- Development of novel vaccine platforms with focus on VSV-based vaccines for emerging infectious diseases
- Pandemic risk assessment using machine learning models to predict spillover events and evaluate pandemic potential
- Improvement of vaccine stability, distribution strategies, and intervention protocols for resource-limited settings
- Translational research focusing on neglected regional pathogens like Kyasanur Forest Disease Virus and other flaviviruses
Publication
- Bhatia B, Tang-Huau TL, Feldmann F, Hanley PW, Rosenke R, Shaia Carl, Marzi A and Feldmann H, Single-dose VSV-based vaccine protects against Kyasanur Forest disease in nonhuman primates, Science Advances, September 2023, PMID: 37672587
- Bharti B, Marzi A, Kimberly MW, Haddock E, Feldmann F and Feldmann H., VSV-based Kyasanur Forest Disease Virus (KFDV) vaccines protect mice from lethal challenge, NPJ Vaccines, 2021 October, PMID: 34907224
- Bharti B*, Hillman C, Stewart P, Rosa P., Probing the role of bba30, a highly conserved gene of the Lyme disease spirochete, throughout the mouse-tick infectious cycle, Infection and Immunity, 2021 October, PMID: 34581605
- Bharti B, Furuyama W, Hoenen T, Feldmann H. and Marzi A., Ebola Virus Glycoprotein Domains Associated with Protective Efficacy, Vaccines, 2021 June, PMID: 34200548
- Solanki AK, Acharya A, Kaushik H, Bhatia B & Garg LC., Molecular docking analysis of Clostridium perfringens beta toxin model with potential inhibitors from the ZINC database., Bioinformation, 2021 June, PMID: 35173385
- Bhatia B, Haddock E, Carl S, Rosenke R, Kimberly MW, Griffin A, Marzi A and Feldmann H., Alkhurma Hemorrhagic Fever Virus causes lethal disease in IFNAR-/- mice, Emerging Microbes & Infections, 2020 December, PMID: 34013842.
- Bhatia B,Feldmann H and Marzi A., Kyasanur Forest Disease and Alkhurma Hemorrhagic Fever Virus-Two Neglected Zoonotic Pathogens., Microorganisms, 2020 September, PMID: 32932653.
- Kaushik H, Deshmukh SK, Solanki AK, Bhatia B and Garg LC., Immunization with recombinant fusion of LTB and linear epitope (40-62) of epsilon toxin elicits protective immune response against the Epsilon toxin of Clostridium perfringens type D., Appl Microbiol Biotechnol. 2019 July, PMID: 31300915.
- Bhatia B,Hillman C, Carrocoi V, Tilly K and Rosa P., Infection history of host shapes pathogenic potential of the Lyme disease spirochete within feeding tick vector, Plos Pathogens, 2018 April, PMID: 29621350.
- Solanki AK, Bhatia B, Kaushik H, Deshmukh SK, Dixit A and Garg LC., Clostridium perfringensbeta toxin DNA prime-protein boost elicits enhanced protective immune response in mice, Appl Microbiol Biotechnol. 2017 Jul;101(14):5699-5708, PMID 28523396
- Bhatia B, Solanki AK, Kaushik H, Dixit A and Garg LC., B-cell epitope of beta toxin of Clostridium perfringens genetically conjugated to a carrier protein: Expression, purification and characterization of the chimeric protein, Protein Expr Purif. 2014 October; 102:38-44, PMID 24996028.
- Bhatia B,Ponia SS,Solanki AK, Dixit A and Garg LC., Identification of glutamate ABC-Transporter component in Clostridium perfringens as a putative drug target, Bioinformation. 2014 July, PMID25187678.
- Bhatia B*,Sudipta Sonar,Seema Khan, and Jayanta Bhattacharya, Pandemic-Proofing: Intercepting Zoonotic Spill-Over Events, Pathogens. 2024 1067; https://doi.org/10.3390/pathogens13121067.
- Bharti Bhatiaand Lalit C Garg (2014): IndianPatent Application No. 58/DEL/2014; Title: "Recombinant subunit vaccine against beta toxin of Clostridium perfringens".
- Amit Kumar Solanki, Bharti Bhatia, Himani Kaushik, Sachin Kumar Deshmukh, Lalit C. Garg (2020):Indian Patent Application No. 202011039302; Title: “A recombinant peptide or peptide conjugate of Clostridium perfringens beta-toxin and a recombinant non-toxic vaccine thereof”.
Invention Report:
- Bharti Bhatia,Heinz Feldmannand Andrea Marzi (2021): Title: “Recombinant Vesicular stomatitis virus vaccine for Kyasanur Forest Disease”.
- 2021 NIH Director’s Award as a part of Laboratory of Virology COVID-19 Research Group.
- 2020 NIAID Merit awardas a part of Laboratory of Virology COVID-19 Research Group
- 01292876246
- BHARTIBHATIA[AT]THSTI[DOT]RES[DOT]IN