Publications

  • Appaiahgari M.B., and Vrati, S. (2010) IMOJEV® : a Yellow Fever virus-based novel Japanese encephalitis vaccine. Expert Review of Vaccines 9 : 1371-1384.
  • Anantpadma, M., Stein, D.A., Vrati, S. (2010) Inhibition of Japanese encephalitis virus replication in cultured cells and mice by a peptideconjugated morpholino oligomer. Journal of Antimicrobial Chemotherpay 65 : 953-961.
  • Bhandari, N., Sharma, P., Taneja, S., Kumar, T., Rongsen-Chandola, T., Appaiahgari, M.B., Mishra, A., Singh, S., Vrati, S.; Rotavirus Vaccine Development Group (2009) A Dose-Escalation Safety and Immunogenicity Study of Live Attenuated Oral Rotavirus Vaccine 116E in Infants: A Randomized, Double-Blind, Placebo-Controlled Trial. Journal of Infectious Diseases 200 : 421-429.
  • Appaiahgari, M.B., Abdin, M.Z., Bansal, K.C., Vrati, S. (2009) Expression of Japanese encephalitis virus envelope protein in transgenic tobacco plants. Journal of Virological Methods 162 : 22-29.
  • Wadhwa N, U.C.M Natchu, Sommerfelt H, Strand TA, Kapoor V, Saini S, Kainth UPS, Bhatnagar S (2011) Oral rehydration solution containing zinc does not reduce during or stool volume of acute diarrhea in hospitalized children: A randomized controlled study. J Pediatr Gastroenterol Nutr 53:161-167.
  • Vashist S, Bhullar D, Vrati S (2010) La Protein Can Simultaneously Bind to Both 3'- and 5'-Noncoding Regions of Japanese Encephalitis Virus Genome. DNA Cell Biol. (in press). Appaiahgari MB, Vrati S (2010) IMOJEV®: a Yellow fever virus-based novel Japanese encephalitis vaccine. Expert Rev Vaccines. 9:1371-84.
  • Anantpadma M, Stein DA, Vrati S (2010) Inhibition of Japanese encephalitis virus replication in cultured cells and mice by a peptideconjugated morpholino oligomer. J Antimicrob Chemother. 65:953-61.

Patent filed:

  • Application No. 1133/DEL/2011; Title: A method and device for detection of anti-transglutaminase antibodies.

Publications originating from Research at THSTI

  • Bharati, K. and Vrati, S. (2012) Viral vaccines in India: An overview. Proc. Natl. Acad. Sci. Sect B. Biol. Sci. (In press :DOI10.1007/s40011-011-0014-9).
  • Anantpadma, M. and Vrati, S. (2011) siRNA mediated suppression of Japanese encephalitis virus replication in cultured cells and mice. Journal of Antimicrobial Chemotherpay 67:444-451.
  • Vashist, S., Bhullar, D., and Vrati, S. (2011) La protein can simultaneously bind to both 3’ and 5’-noncoding regions of Japanese encephalitis virus genome. DNA and Cell Biology 30:339-346.
  • Medigeshi GR. Mosquito-borne flaviviruses: overview of viral life-cycle and hostvirus interactions. Future Virology 2011 2011/09/01;6(9):1075-89.
  • Sudha VB, Ganesan S, Pazhani GP, Ramamurthy T, Nair GB, Venkatasubramanian P. 2012. Storing drinking-water in copper pots kills contaminating diarrhoeagenic bacteria. J Health PopulNutr. 30(1):17-21.
  • Sarkar BL, Kanungo S, Nair GB. 2012. How endemic is cholera in India?Indian J Med Res.135:246-8.
  • Hajela N, Nair GB, Abraham P, Ganguly NK. 2012. Health impact of probiotics – visionand opportunities.Gut Pathog. 4(1):1.
  • Naha A, Pazhani GP, Ganguly M, Ghosh S, Ramamurthy T, Nandy RK, Nair GB, Takeda Y, Mukhopadhyay AK. 2012. Development and evaluation of a PCR assay for tracking the emergence and dissemination of Haitian variant ctxB in Vibrio cholerae O1 strains isolated from Kolkata. India. J ClinMicrobiol. 50(5):1733-6.
  • Nahar S, Sultana M, Naser MN, Nair GB, Watanabe H, Ohnishi M, Yamamoto S, Endtz H, Cravioto A, Sack RB, Hasan NA, Sadique A, Huq A, Colwell RR, Alam M. 2011. Role of Shrimp Chitin in the Ecology of Toxigenic Vibrio cholerae and Cholera Transmission. Front Microbiol. 2:260.E.Pub Jan 4.
  • Sinha A, Sengupta S, Guin S, Dutta S, Ghosh S, Mukherjee P, Mukhopadhyay AK, Ramamurthy T, Takeda Y, Kurakawa T, Nomoto K, Nair GB, Nandy RK. 2011. Culture-independent real-time PCR reveals extensive polymicrobial infections in hospitalized diarrhoea cases in Kolkata, India. ClinMicrobiol Infect. doi: 10.1111/j.1469-0691.2011.03746.x.
  • Clemens J, Shin S, Sur D, Nair GB, Holmgren J. 2011. New-generation vaccines against cholera. Nat Rev GastroenterolHepatol. 8(12):701-10. doi:10.1038/nrgastro.2011.174.
  • Sur D, Kanungo S, Sah B, Manna B, Ali M, Paisley AM, Niyogi SK, Park JK, Sarkar B, Puri MK, Kim DR, Deen JL, Holmgren J, Carbis R, Rao R, Nguyen TV, Han SH, Attridge S, Donner A, Ganguly NK, Bhattacharya SK, Nair GB, Clemens JD, Lopez AL.
  • 2011. Efficacy of a low-cost, inactivated whole cell oral cholera vaccine: results from 3 years of follow-up of a randomised, controlled trial. PLoSNegl Trop Dis. 5(10):e1289.
  • Bhatnagar S, Wadhwa N, Aneja S, Lodha R, Kabra SK, Natchu UC, Sommerfelt H, Dutta AK, Chandra J, Rath B, Sharma M, Sharma VK, Kumari M and Strand TA. Zinc as adjunct treatment in infants aged between 7 and 120 days with probable serious bacterial infection: a randomised, doubleblind, placebo-controlled trial (accepted for publication by Lancet)
  • Wadhwa N, UCM Natchu, Sommerfelt H, Strand TA, Kapoor V, Saini S, Kainth UPS and Bhatnagar S. Oral rehydration solution is a poor vehicle for zinc in the treatment of acute childhood diarrhea. J Pediatr Gastroenterol Nutr. 2011 Aug; 53(2):161-7.
  • Gulani A, Bhatnagar S, Sachdev HP. Neonatal zinc supplementation for prevention of mortality and morbidity in breastfed low birth weight infants: systematic review of randomized controlled trials. Indian Pediatr. 2011 Feb 7;48(2):111-7.
  • Yadav P, Das P, Mirdha BR, Gupta SD, Bhatnagar S, Pandey RM, Makharia GK. Current spectrum of malabsorption syndrome in adults in India. Indian J Gastroenterol. 2011 Feb;30(1):22-8.
  • KN Beeesabathuni, UC Natchu. Production and Distribution of a Therapeutic Nutritional Product for Severe Acute Malnutrition in India: Opportunities and Challenges. Indian Pediatr 2010 Aug 7;47(8):702-6.
  • Goldie SJ, Sweet S, Carvalho N, Natchu UC, Hu D. Alternative strategies to reduce maternal mortality in India: a cost-effectiveness analysis. PLoS Med. 2010 Apr 20;7(4):e1000264
  • Lee Y*, Awasthi A *, Nir Yosef, Francisco Quintana, Sheng Xiao, Sharon Kunder, Aviv Regev Sobel R, Kuchroo VK. Induction and molecular signature of pathogenic TH 17 cells. Nature. Immunology. [Shared first and senior author ]. 2012 Oct;13(10):991-9.
  • Kuchroo VK, Awasthi A. Emerging new roles of Th17 cells. European Journal of Immunology. 2012 Sep;42(9):2211-4.

THSTI Publications from External Collaborations

  • Ravikiran M. Raju, Meera Unnikrishnan, Daniel H. F. Rubin, Vidhya Krishnamoorthy, Olga Kandror, Tatos N. Akopian, Alfred L. Goldberg, Eric J. Rubin
    Mycobacterium tuberculosis ClpP1 and ClpP2 Function Together in Protein Degradation and Are Required for Viability in vitro and During Infection. Research Article | 16 Feb 2012 | PLoS Pathogens. doi:10.1371/journal.ppat.1002511

Publications originating from Research at THSTI

  • Agarwal,N.,Pareek,M.,Thakur,P.,Pathak,V.(2012) Functional characterization of EngA.MS,a P-loop GTPase of Mycobacterium smegmatis.PLoSOne.7(4):e34571.
  • Appaiahgari,M.B.,Vrati,S.(2012) Clinical development of iMOJE -a recombinant Japanese encephalitis vaccine (JE-CV).ExpertOpinBioiTher.12:1251-1263.
  • Beena,Joshi,S.,Kurnar,N.,Kidwai,S.,Singh,R.,Rawat,D.S.(20U) Synthesis and antitubercuIar activity evaluation of novelunsymmetricalcyclohexane1,2- diamine derivatives.Arch Pharm (Weinheim).345:896-901.
  • Bharati,K.,Vrati,S.(2012)Vira vl accines in lndia: An overview. Proc. Natl. Acad. Sci. Sect B. Biol. Sci.82:181-198.
  • Bhatnagar,S.,Wadhwa,N.,Aneja,S.,Lodha,R.,Kabra,S.K.,Natchu,U.C.,Sommerfelt,H.,Dutta,A.K.,Chandra,J., Rath, B., Sharma, M.,Sharma,V.K., Kumari,M.,Strand, T.A. (2012) Zinc as adjunct treatment in infants aged between 7 and 120 days with probable serious bacterial infection: a randomised, double-blind, placebo­ controlled trial.Lancet.379(9831):2072-8.
  • Chandola,T.R.,Taneja,S.,Goyal,N.,Rathore,S.S.,Appaiahgari,M.B.,Mishra,A.,Singh,S.,Vrati,S.,and Bhandari, N.(2012) Descriptiveepidemiologyofrotavirus infection in a community inNorth India.Epidemiollnfect.8:1-7.
  • Deb,A.,Kanungo,S.,Deb,M.,Nair,G.B.(2012) lmpact of clima techangeon health and strategies for mitigation and adaptation. WHOSouth-EastAsia Journalof Pub Health1:8-19.
  • Gupta,S.S.,Nair,G.B.,Arora,N.K.,Ganguly,N.K.(2013) Vaccine development and deployment: Opportunities and challenges in India.Vaccine.(31S):B43-B53.
  • Gupta,S., Dudha,N.,Appaiahgari,M.B., Bharati,K.,Gupta,D.,Gupta,Y.,Kumar,K., Gabrani, R.,Sharma,S.K., Gupta,A.,Chaudhary,V.K.,Vrati, S.(2012) Molecular cloning and characterization of Chikungunya virus genes from Indian isolate of2006 outbreak. Journal of Pharmacy Research.5:3860-63.
  • Haldar S,Sankhyan N,Sharma N,BansalA,Jain V,Gupta VK,Juneja M,Mishra D,KapilA,Singh UB,Prasad HK, GulatiS,Kalra V,Tyagi JS (2012).Detection of Mycobacterium tuberculosis GlcB or HspX antigens or devR DNA impacts the rapid diagnosis of tuberculous meningitis in children.e44630PLoSONE.
  • Hajela,N.,Nair,G.B.,Abraham,P.,Ganguly,N.K.(2012) Health impact of probiotics-vision and opportunities.Gut Pathog.4(1):1.
  • Haridas,V.,RajgokuI,K.S.,Sadanandan,S.,AgrawaI,T.,Sharvani,V.,Gopalakrishna,M.V.S.,Bijesh M.B.,Kumawat, K.L.,Basu,A.,Medigeshi,G.R. (2013) Bispidine-amino acid conjugates act as a novelscaffold for the design of antiviralsthat block Japanese encephalitisvirus replication.PLoS NeglTropDis.7:e2005.
  • Kalia,M.,Renu,K.,Sharma,M.,Nain,M.,Vrati,S.(2013) Japanese encephalitis virus infects neuronalcells through a clathrinindependentendocytic mechanism.JVirology. 87(1):148.
  • Lantagne,D.,Nair,G.B.,Lanata,C.L.,Cravioto,A.(2012) The origin of cholera inHaiti. Journalof Disaster Research.7:759-767.
  • Natchu,U.C.,Bhatnagar,S.(2013) Diarrhoea inchildren:identifyingthecauseand burden.Lancet.382(9888):184-6.
  • Natchu,U.C.,Liu,E.,Duggan,C.,Msamanga,G.,Peterson,K.,Aboud,S.,Spiegelman,D.,Fawzi,W.(2012) Exclusive breastfeedingreduces risk of mortality in infants up to 6 mo ofage born to HIV--positive Tanzanian women.Am JClin Nutr.96(5):1071-8.
  • Sreejith,R.,Rana,J.,Dudha,N.,Kumar,K.,Gabrani,R.,Sharma,S.K.,Gupta,A.,Vrati,s.,Chaudhary,V.K.,Gupta, s.(2012)MappinginteractionsofChikungunya virus non structural proteins. Virus Res.169:231-236.
  • You,Y.A.,Ali,M.,Kanungo, S.,Sah,B.,Manna,B.,Puri,M.,Nair,G.B.,Bhattacharya, S.K.,Deen, J.L.,Lopez,A.L., Wierzba, T.F.,Clemens, J.,Sur, D. (2013) Risk Map of Cholera Infection for Vaccine Deployment: The Eastern Kolkata Case.PLoSOne.8(8):e71173.
  • Vohra,P.,Bhatnagar,S.(2012) Childhooddiarrhea.JIndian MedAssoc.110(11):848-9.


THSTI Publications from External Collaborations

  • Ali,M.,Sur,D.,You,Y.A.,Kanungo,S.,Sah,B.,Manna,B.,Puri,M.,Wierzba,T.F.,Donner,A.,Nair,G.B.,Bhattacharya, S.K.,Dhingra,M.S.,Deen,J.L.,Lopez,A.L.,Clemens,J.(2013) Herd protection by a bivalent killed whole-celloral cholera vaccinein theslumsofKolkata,lndia.Clin Infect Dis.56(8):1123.
  • Bhat,A.S.,Chaturvedi,M.K.,Saini,S.,Bhatnagar,S.G, upta,N.,Sapra,S.,Gupta,S.D.,Kabra, M.(2013) Prevalence of celiac disease in Indian children with Down syndrome and its clinical and laboratory predictors. lndianJ Pediatr.80(2):114-7.
  • Chattopadhyay,S.,Patra,R.,Chatterjee,R.,De,R.,Alam,J.,Ramamurthy,T.,Chowdhury,A.,Nair,G.B.,Berg, E.D., Mukhopadhyay,A.K.(2012) Distinct repeat motifs at the C-terminalregion of CagA. of Helicobacter pylori strains isolated fromdiseased patients andasymptomatic individualsinWest Bengal,India.Gut Pathog.4(1):4.
  • Chowdhury,G.,Pazhani,G.P.,Dutta,D.,Guin,S.,Dutta,S.,Ghosh,S.,Izumiya,H.,Asakura,M.,Yamasaki,S.,Takeda,Y., Arakawa,E.,Watanabe,H.,Mukhopadhyay, A.K.,Bhattacharya,M.K.,Rajendren, K., Nair,G.B.,Ramamurthy,T.(2012) Vibriofluvialisin patients with diarrhea, Kolkata, lndia. EmergInfect Dis.18(11):1868-3.
  • Das, B.,Martinez,E.,Midonet,C.,Barre,F.X. (2013) Integrative mobile elements exploiting Xer recombination.Trends inMicrobial.21:23-30.
  • Dhiman,R.,Periasamy,S.,Barnes,P.F.,Jaiswai,A.G.,Paidipally,P.,Barnes,A.B.,Tvinnereim,A., Vankayalapati,R. (2012) NKl.l+ cells and IL-22 regulate vaccine-induced protective immunity against challenge with Mycobacterium tuberculosis.J Immunol.189(2):897-905.
  • Dutta,S.,Guin,S.,Ghosh,S.,Pazhani,G.P.,Rajendran,K.,Bhattacharya,M.K.,Takeda,Y.,Nair,G.B.,Ramamurthy,T. (2013) Trends in the Prevalence of Diarrheagenic Escherichia coli among Hospitalized Diarrheal Patients inKolkata,India.PLoS One.8(2):e56068.
  • Dwivedi,S.,Das,B.K.,Aneja,S.,Sharma,S.,Chaturvedi,M.K.,Kahn,G.,Fitzwater,S.P.,Chandran,A.,Wadhwa,N., Bhatnagar,S.(2013) Group B StreptococcalMeningitis in Infants Beyond the NeonatalPeriod.Indian J Pediatr. [Epub ahead of print]
  • Griffin, J.E.*, Pandey, A.K.*, Mizrahi, V., McKinney, J.D., Sassetti, C.M. (2012) Cholesterol catabolism by Mycobacterium tuberculosis requires transcriptional and metabolic adaptations. Chern Bioi. (19): 218-227.*contributed equallytothiswork
  • lsac,S.R.,Nair,G.B.,Singh,D.V.(2012) Purification and Characterization of Cytotoxin Produced by a ClinicalIsolate ofVibriocholerae 054TV113.ApplBiochem Biotechnol.167:809-23.
  • Kanungo,S.,Sur,D.,Ali,M.,You,Y.A.,Pal,D.,Manna,B.,Niyogi,S.K.,Sarkar,B.,Bhattacharya,S.K.,Clemens,J.D., Nair,G.B. (2012) Clinical,epidemiological,and spatial characteristics of Vibrio parahaemolyticus diarrhea and cholera in the urbanslumsofKolkata,lndia.BMC Public Health12(1):830.
  • Kao, c.c., Fan,B.,Chinnaswamy,S.,Cai, H.,Ranjith-Kumar C.T.,Deval, J. (2012) Assays for RNA Synthesis and Replicationby theHepatitisCVirus.Frontiersin Biology.7(3):233-245 Kuchroo, V.K.,Awasthi,A.(2012) Emergingnew roles ofTh17 cells.EurJ lmmunol.42(9):2211-4.
  • Kumar,N.,Borth,N.(2012) Flow-cytometry and Cellsorting:An efficient approach to investigate productivity and cellphysiologyin mammaliancellfactories.Methods.56(3):366-74.
  • Kumar,N.,Sharma,G.,Kaur,G.,Tandon,N.,Bhatnagar, s., Mehra,N. (2012) Major histo compatibility complex class Ichain related gene-A microsatellite polymorphism shows secondary association with type 1diabetes and celiac diseasein North Indians. Tissue Antigens. 80(4):356-62.
  • Kumar,R.,Andrabi,R.,Tiwari,A.,SomiSankaran,P.,Wig.N.,Dutta,D.,Sankhyan,A.,Khan,L,Sinha,S.,Luthra,K.(2012) A Novel strategy for efficient production ofanti-V3 humansc Fvs againstHIV-1dadeC.BMC Biotechnol.l2(1):87.
  • Kurakawa,T.,Kubota,H.,Tsuji,H.,Matsuda,K.,Takahashi,T.,Ramamurthy,T.,Nair,GB.,Takeda,Y.,Nomoto,K. (2012) Intestinal Entero bacteria ceae and Escherichia coli populations in Japanese adults demonstrated by the reverse transcription-quantitative PCR and the done library analyses. J MicrobioiMethods.92:213-219
  • Larsson,C.,Luna,B.,Ammerman,N.C.,Maiga,M.,Agarwal,N.,Bishai,W.R.(2012) Gene expression of Mycobacterium tuberculosis putative transcription factors whiB1-7in redoxenvironments. PLoS0ne.7(7):e37516.
  • Lee,Y.*,Awasthi,A.*,Yosef,N.,Quintana,F.,Xiao,S.,Kunder,S.,Regev,A.,Sobel,R.,Kuchroo,V.K.(2012) Induction and molecularsignatureofpathogenicTH17cells.Natlmmunol.13:991-9.*[Shared first and senior author].
  • Naha,A.,Chowdhury,G.,Ghosh-Banerjee,J.,Senoh,M.,Takahashi,T., Ley,B.,Thriemer,K.,Deen, J.,Seidlein,LV., Ali, S.M.,Khatib,A., Ramamurthy,T., Nandy,R.K.,Nair,G.B., Takeda,Y., Mukhopadhyay,A.K. (2013) Molecular Characterization of High-Level-Cholera-Toxin-Producing El Tor Variant Vibrio cholerae Strains in the Zanzibar Archipelago ofTanzania.J Clin Microbial.51(3):1040-5.
  • Nair, G.B., Ramamurthy, T., Sur, D., Kurakawa, T., Takahashi, T., Nomoto, K., Takeda, Y. (2012) Vibrio cholerae/mimicus in fecalmicrobiota of healthy children incholera endemic urban slum settingin Kolkata,lndia. Microbiollmmunol. 56(11):789-91.
  • Neogi, S.B., Islam, M.S., Nair,G.B., Yamasaki, s., Lara, R.J. (2012) Occurrence and distribution of plankton­ associated and free livingtoxigenic Vibrio cholerae in a tropicalestuary of a cholera endemic zone.Wetlands Ecol Manage.20:271-285.
  • Octavia,S.,Salim,A.,Kurniawan,J.,Lam,C.,Leung,Q.,Ahsan,S.,Reeves,R.P.,Nair,G.B.,Lan,R.(2013) Population structure and evolution of non-01/non-0139 Vibrio cholerae by multilocus sequence typing. PLoS One. 8(6):e65342.
  • Pal, R.R., Bag, S., Dasgupta,S., Das, B., Bhadra,RK. (2012) Functional characterization of the stringent response regulatory gene dksA ofVibriocholerae and itsrolein modulation of virulence phenotypes.J.Bacteriol.194:5638-5648.
  • Patra, R., Chattopadhyay, S., De, R., Ghosh, P. Ganguly, M., Chowdhury, A., Ramamurthy, T., Nair, G.B., Mukhopadhyay,A.K. (2012) Multiple infection and microdiversity among Helicobacter pyloriisolates in a single hostin India.PLoSOne.7:e43370.
  • Ramachandran, P., Fitzwater, S.P., Aneja, S., Verghese, V.P., Kumar, V., Nedunchelian, K., Wadhwa, N., Veeraraghavan,B.,Kumar,R.,Meeran,M.,Kapil,A.,Jasmine,S., Kumar,A., Suresh,S.,Bhatnagar,S.,Thomas,K., Awasthi,S., Santosham,M.,Chandran,A. (2013) Prospective multi-centre sentinelsurveillance for Haemophilus influenzaetype b&other bacterial meningitis in Indian children.Indian J MedRes.137(4):712-20.
  • Sarkar,B.L.,Kanungo,S.,Nair,G.B.(2012) How endemicis cholera in India? Indian J MedRes.135:246-8.
  • Senoh,M.,Ghosh-Bane ee.J.,Ramamurthy,T.,Colwell,R.R.,Miyoshi,S.,Nair,G.B.,Takeda,Y.(2012) Conversion of viable butnonculturableentericbacteriatoculturable byco-culturewitheukaryotic cells.Microbiollmmunol.56:342-5.
  • Shenoy,G.N.;Chatterjee,P,Kaw,S.;Mukherjee,S.;Rathore,D.K.;Bal,V.;Rath,S.;George,A.;(2012) Recruitmentof memory B cells to lymph nodes remote from the site of immunization requires an inflammatory stimulus. J lmmunol.189(2):521-8.
  • Singh,P.,Das,P.,Jain,A.K.,Mathan,M.,Mathur,M.,Bhat,A.S.,Varma,S.,Chaturvedi,M.K.,Gupta,S.D.,Bhatnagar, S.{2013) Microscopic ColitisinChildren With Chronic Diarrhea.J PediatrGastroenterolNutr.57(2):240-4.
  • Subba-Reddy,C.V., Tragesser, B., Xu, Z., Stein, B.,Ranjith-Kumar,C.T.,Kao,C.C. (2012) RNA Synthesis by the Brome MosaicVirus RNA-Dependent RNA Polymerase in Human Cells Reveals Requirementsfor De Novo Initiation and Protein-Protein lnteraction.JVirol86:4317-4327.
  • Sudha, V.B., Ganesan,S., Pazhani, G.P., Ramamurthy, T., Nair, G.B., Venkatasubramanian, P. (2012) Storing drinking-water in copper-pots kills contaminating diarrhoeagenic bacteria. JHealth PopulNutr.30:17-21.
  • Sumi, A, Rajendran, K., Ramamurthy, T., Krishnan, T., Nair, G.B., Harigane, K., Kobayashi, N. (2013} Effect of temperature,relativehumidityand rain fall on rotavirus infections in Kolkata, India.Epidemiollnfect.141(8):1652-1661.
  • Vaughan,R.,Li,Y.,Fan,B.,Ranjith-Kumar,C.T.,Kao,C.C.(2012) RNA bindingby the NS3 protease ofthe hepatitis C virus.Virus Res.169(1}:80-90.
  • Wadhwa,N.,Chandran,A.,Aneja,S.,Lodha,R.,Kabra,S.K.,Chaturvedi,M.K.,Sodhi,J.,Fitzwater,S.P.,Chandra,J., Rath,B.,Kainth,U.S.,Saini,S.,Black,R.E.,Santosham,M.,Bhatnagar,S.(2013) Efficacy of zinc givenas an adjunct in the treatment of severe and very severe neumonia in hospitalized children 2-24 mo of age: a randomized, double-blind,placebo-controlled trial.Am JClin Nutr.97(6):1387-94.
  • Vi,G.,Deval,J.,Fan,B.,Cai,H.,Soulard,C.,Ranjith-Kumar,C.T.,Smith,D.B.,Blatt,L.,Beigelman,L., Kao,C.C.(2012) Comparative Inhibition of the Hepatitis C Virus RNA Polymerase by VX-222 and Filibuvir- a BiochemicalStudy. AntimicrobAgents Chemother.56 (2):830-837.
  • Yosef,N., Shalek,A.K.,Gaublomme, J.T.,Jin, H.,Lee,Y.,Awasthi,A.,Wu,C., Karwacz, K.,Xiao,S., Jorgolli, M., Gennert,D.,Satija,R.,Shakya,A.,Lu,D.Y.,Trombetta,J.J.,Pillai,M.R., Ratcliffe,P.J.,Coleman, M.L.,Bix,M.,Tantin,D., Park,H., Kuchroo,V.K.,Regev, A. (2013} Dynamic regulatory network controlling TH17 cell differentiation. Nature.496:461-8.

Book Chapters

  • Bhatnagar,S.,Singh,M.,Chaturvedi,M.(2012).Acute Gastroenteritis.Medical Emergencies in Children.Singh,M.(Ed.),(4th ed.) pp.385-405SagarPublicationslndia.
  • Bhatnagar,S.,Vohra,P.,Kunnekal,K.(2013).Antimicrobial therapy in acutegastroenteritis. N.Shah,T.Singhal(Eds.), RationalAntimicrobialPracticein Pediatrics(2nded.) pp.189-201. IndianAcademyofPediatrics.
  • Das,B.,& Nair,G.B.(2012).The genomics of Cholera.In Karen E.Nelson & Barbara jones-Nelson (Eds.),'Genomics Applicationsfor the Developing World'pp.21-38. New York, USA: Springer publication.
  • Sharma, D., Surolia, A (2013). Pathway targeting, antimycobacterial drug design. In Werner Dubitzky, Olaf Wolkenhauer,Kwang-Hyun Cho,HirokiYokota (Eds.),Encyclopedia of Systems Biology (pp1656-1659).NewYork, USA:Springer.
  • Nair,G.B.,Neerja,H.,Ramamurthy,T.,& Takeda,Y.(2012}.Probiotics and Diarrhea in low and middle -income countries. In G.B.Nair andY.Takeda (Eds.},'Health Impact of Probiotics-Vision & Opportunities' pp 36-47.New Delhi,India:Elsevier.
  • Ramamurthy, T., Mukhopadhyay, A.K., Nandy, R.K.,& Nair,G.B. (2013}.Molecular typing of Vibrio cholerae: Imprints in the Epidemiology of Cholera. In l.de Filippis and M.L. McKee (Eds.),'Molecular Typing in Bacterial Infections'pp.53-72.NewYork,USA: Humana Press.

Books

  • Nair,G.B.,&Takeda,Y.(Eds.}.2012.Health lmpactofProbiotics-Vision&Opportunities.New Delhi,India:Elsevier.

Publications originating from Research at THSTI

  • Pareek S, Roy S, Kumari B, Jain P, Banerjee A, Vrati S (2014) miR-155 induction in microglial cellssuppresses Japanese Encephalitis Virus replication and negatively modulates innate immuneresponses. Journal of Neuroinflammation11 : 97
  • Sharma M, Bhattacharya S, Nain M, Kaur M, Sood V, Gupta V, Khasa R, Abdin MZ , Vrati S, Kalia M(2014) Japanese Encephalitis Virus replication is negatively regulated by autophagy and occurson LC3-I and EDEM 1 containing membranes. Autophagy Volume 10, Issue 9.
  • Bhandari N, Rongsen-Chandola T, Bavdekar A, John J, Antony K, Taneja S, Goyal N, Kawade A, Kang G, Rathore SS , Juvekar S, Muliyil J, Arya A, Shaikh H, Abraham V, Vrati S, Proschan M, Kohberger R, Thiry G, Glass R, Greenberg HB, Curlin G, Mohan K, Harshavardhan GV , Prasad S, RaoTS ,Boslego J, Bhan MK (2014) Efficacy of a monovalent human-bovine (116E) rotavirus vaccine in Indian infants: a randomised, double-blind, placebo-controlled trial. Lancet S0140-6736 : 62630-6.
  • Appaiahgari MB, Glass R, Singh S, Taneja S, Rongsen-Chandola T, Bhandari N, Mishra S, Vrati S.(2014) Transplacental rotavirus IgG interferes with immune response to live oral rotavirus vaccine ORV -116E in Indian infants. Vaccine 3; 32(6):651-656.
  • Bhattacharyya S, Sen U, Vrati S. (2014) Regulated IRE 1-dependent decay pathway is activated during Japanese encephalitis virus-induced unfolded protein response and benefits viral replication. J Gen Virol. 95(Pt 1):71-79.
  • Kalia M, Khasa R, Sharma M, Nain M, Vrati S. (2013) Japanese encephalitis virus infects neuronalcells through a clathrin-independent endocytic mechanism. J Virol 87(1):148-162.Bhattacharyya S. Can’t RIDD off viruses.Frontiers in Microbiology, section virology. (2014).(Invited review;In press)
  • Nimesh Gupta, PushpaHegde, MaximeLecerf, Minu Nain, ManpreetKaur, ManjulaKalia, SudhanshuVrati, JagadeeshBayry, SebastienLacroix-Desmazes and Srini V. Kaveri (2014) Japanese encephalitis virus expands regulatory T cells by increasing the expression of PD-L1on dendritic cells E ur. J. Immunol. 2014 May;44(5):1363-74.
  • Pal A, Panigrahi R, Biswas A, Datta S, Sarkar N, Guha SK, Saha B, Banerjee A, Chakrabarti S,Chakravarty R. (2013) Influence of HIV-associated degree of immune suppression on molecular heterogeneity of hepatitis B virus among HIV co-infected patients. Virology.5;436(1):134-42.
  • Xia Jiang, Tatsuo Kanda, Shuang Wu, Masato Nakamura, Tatsuo Miyamura, Shingo Nakamoto, Arup Banerjee, Osamu Yokosuka. (2014) Regulation of miRNA by HBV infection and their possible association with control of innate immunity. World J Gastroenterol, (In press)
  • Yuen-Yi Tseng, BrandenMoriarity, Wuming Gong, Hiroko Kawakami, Ryutaro Akiyama, Ashutosh Tiwari, Peter Ronning, Brian Reuland, M. O’Sullivan, David Largaespada, York Marahrens, Kathryn Schwertfeger, Yasuhiko Kawakami, AnindyaBagchi. (2014) PVT1-Dependence in Cancer with MYC Copy Number Increase. Nature (In press)
  • Haridas,V., Rajgokul, K. S., Sadanandan, S., Agrawal, T., Sharvani, V., Gopalakrishna,M. V. S., Bijesh, M.B., Kumawat, K. L., Basu, A., and Medigeshi, G. R. (2013) Bispidine-Amino Acid Conjugates Act as aNovel Scaffold for the Design of Antivirals That Block Japanese EncephalitisVirus Replication. PLoSNegl Trop Dis7, e2005
  • Agrawal,T., Sharvani, V., Nair, D., and Medigeshi,G. R. (2013) Japanese Encephalitis Virus Disrupts Cell-Cell Junctions andAffects the Epithelial Permeability Barrier Functions. PLoS ONE 8, e69465.
  • Agrawal,T., Schu, P., and Medigeshi, G. R.(2013) Adaptor protein complexes-1 and 3 are involved at distinct stages offlavivirus life-cycle. Sci Rep3, 1813
  • Agrawal, T., Sharvani, V., Nair, D., and Medigeshi, G. R. (2013) Japanese Encephalitis Virus Disrupts Cell-Cell Junctions and Affects the Epithelial Permeability Barrier Functions. PLoS ONE 8, e69465
  • Kakumani, P. K., Ponia, S. S., Shanmugam, R. K., Sood, V., Chinnappan, M., Banerjea, A. C., Medigeshi, G. R., Malhotra, P., Mukherjee, S. K., and Bhatnagar, R. K. (2013) Role of RNA Interference (RNA i) in Dengue Virus Replication and Identification of NS 4B as an RNA i Suppressor. Journal oF Virology 87, 8870-8883
  • Eira Choudhary, William Bishai, and NisheethAgarwal. (2014) Expression of a subset of heat stress induced genes of Mycobacterium tuberculosis is regulated by 3’,5’-cyclic AM P.PLoS One. 2014 Feb 28;9(2):e89759
  • Chandola TR, Taneja S, Goyal N, Rathore SS , AppaiahgariMB,et.al. (2013). Descriptive epidemiology of rotavirus infection in a community in North India.Epidemiol Infect, 141(10): 2094-2100
  • Appaiahgari MB, et.al.,(2014) Transplacental rotavirus IgG interferes with immune response to live oral rotavirus vaccine ORV -116E in Indian infants. Vaccine. 3;32(6):651-6
  • Das B., Martinez E.,Midonet C., and Barre F.X. (2013): Integrative mobile elements exploitingXerrecombination.Trends in Microbiol.TrendsMicrobiol. 21:23-30
  • Zaw MT , Yamasaki E, Yamamoto S, Nair GB, Kawamoto K, Kurazono H. (2013). Uropathogenic specific protein gene, highly distributed in extraintestinaluropathogenic Escherichia coli, encodes a new member of H-N-H nuclease superfamily. Gut Pathogens 5(1):13.
  • Barman S, Koley H, Ramamurthy T, Chakrabarti MK, Shinoda S, Nair GB, Takeda Y. (2013). Protective immunity by oral immunization with heat-killed Shigella strains in a guinea pig colitis model. Microbiology and Immunology 57(11):762-71
  • You YA , Ali M, Kanungo S, Sah B, Manna B, Puri M, Nair GB, Bhattacharya SK,Convertino M, Deen JL, Lopez AL ,Wierzba TF, Clemens J, Sur D. (2013). Risk map ofcholera infection for vaccine deployment: the eastern Kolkata case. PLoS One. 8(8):e71173
  • Yamasaki E, Sakamoto R, Matsumoto T, Morimatsu F, Kurazono T, Hiroi T, Nair GB, Kurazono H.(2013). Development of an immunochromatographic test strip for detection of cholera toxin. BioMed Research International 2013;2013:679038
  • De R., Ghosh Banerjee J., Sen Gupta S., Nair GB. (2013). The role of Vibrio choleraegenotyping in Africa. The Journal of Infectious Diseases. 208 Suppl 1:S32-8.
  • Bhattacharya SK, Sur D, Ali M, Kanungo S, You YA , Manna B, Sah B, NiyogiSK,Park JK, Sarkar B, Puri MK, Kim DR, Deen JL, Holmgren J, Carbis R, Dhingra MS , Donner A, Nair GB, Lopez AL ,Wierzba TF, Clemens JD. (2013). 5 year efficacy of a bivalent killed whole-cell oral cholera vaccine in Kolkata, India: a cluster-randomised, double-blind, placebo-controlled trial. Lancet Infect Dis. 13(12):1050-6
  • GhoshTS , Gupta SS , Nair GB, Mande SS . (2013) Insilico analysis of antibiotic resistance genes in the gut microflora of individuals from diverse geographies and age-groups. PLoS One. 8(12):e83823
  • Hajela N, Nair G.B, Ramakrishna B.S. &Ganguly NK.(2014). Probiotic foods: Can their increasing use in India ameliorate the burden of chronic lifestyle disorders? Indian J Med Res. 139: 19-26
  • Banerjee R.*, Das B.*, Nair G.B., Basak S. (2014): Dynamics in genome evolution of Vibrio cholerae. Infect. Genet.Evol. 23: 32-41 (*Equally contributed)
  • Kar SK, Sah B, Patnaik B, Kim YH , Kerketta AS , Shin S, Rath SB, Ali M, Mogasale V, Khuntia HK, Bhattachan A, You YA , Puri MK, Lopez AL , Maskery B, Nair GB, Clemens JD, Wierzba TF.(2014). Mass vaccination with a new, less expensive oral cholera vaccine using public health infrastructure in India: the odishamodel.PLoS Neglected Tropical Diseases.8(2):e2629.
  • Ghosh T.S., Sen Gupta S., Bhattacharya T., Yadav D., Barik A., Chowdhury A., Das B., Mande S.S., Nair G.B. (2014): Gut microbiomes of Indian children of varying nutritional status. Plos One 9(4) e95547.
  • Malla S, Dumre SP, Shakya G, Kansakar P, Rai B, Hossain A, Nair GB, Albert MJ, Sack D, Baker S, Rahman M. (2014). The challenges and successes of implementing a sustainable antimicrobial resistance surveillance programme in Nepal. BMC Public Health. 14(1):269
  • Das B., Nair G.B., Bhadra R.K. (2014): Acquisition and dissemination mechanisms of CTX Φin Vibrio cholerae: New paradigm for difresidents. World J Med Genet (In press)
  • Bag S., Das B., Dasgupta S., and Bhadra R.K. (2014): Mutational analysis of the (p)pp Gpp synthetase activity of the Rel enzyme of Mycobacterium tuberculosis. Arch. Microbiol. (In press)
  • Chauhan P, Reddy PV, Singh R, Jaisinghani N, Gandotra S and Tyagi AK.(2013) Secretory phosphatases deficient mutant of Mycobacterium tuberculosis imparts protection at the primary site of infection in guinea pigs. pLOS One18;8(10):e77930
  • Kumar N, Kapoor E, Singh R, Kidwai S, Kumbukgolla W, Bhagat S and Rawat DS. (2013) Synthesis and antibacterial/antitubercular activity evaluation of symmetrical trans-cyclohexane-1,4-diamine derivatives. Ind J Chem 52B 1441 – 1450
  • Singh R, Singh M, Arora G, Kumar S, Tiwari P, Kidwai S. (2013) Polyphosphate deficiency in mycobacterium tuberculosis is associated with enhanced drug susceptibility and impaired growth in guinea pigs. J Bacteriol 195 2839 – 51
  • Beena, Joshi S, Kumar N, Kidwai S, Singh R, Rawat DS. (2012) Synthesis and antitubercular activity evaluation of novel unsymmetrical cyclohexane-1,2-diamine derivatives. Arch Phar 345 (11) 896-901
  • Cascales E, Atmakuri K, Sarkar M, and Christie P. (2013) DNA Substrate-Induced Activation of the Agrobacterium VirB/VirD4 Type IV Secretion System. J. Bacteriol.195: 2691-2704
  • Khattar SK, Samal S, Labranche CC , Montefiori DC, Collins PL, Samal SK. Comparative Immunogenicity of HIV-1 gp160, gp140 and gp120 Expressed by Live Attenuated Newcastle Disease Virus Vector.PLoS One. 2014 Jan 29;9(1)
  • Khattar SK, Nayak B, Kim SH , Xiao S, Samal S, Paldurai A, Buchholz UJ, Collins PL, Samal SK. Evaluation of the replication, pathogenicity, and immunogenicity of avian paramyxovirus (APMV ) serotypes 2, 3, 4, 5, 7, and 9 in rhesus macaques. PLoS One. 2013 Oct 10
  • Samal S,Khattar SK, Paldurai A, Palaniyandi S, Zhu X, Collins PL, SamalSK.Mutations in the cytoplasmic domain of the Newcastle disease virus fusion protein conferhyperfusogenic phenotypes modulating viral replication and pathogenicity.JVirol. 2013 Sep;87(18):10083-93.
  • TriptiShrivastava, K. Mino, NigarBabayeva, OxanaBaranosky, A. Rizzino, Tahir H Tahirov. (2014) Structural basis of Ets1 activation by Runx1. L eukemia. Murphy M.K., Ye L., Pan R., Boliar S., Sethi A., Tian J., Pfafferot K., Karita E., Allen S.A., Cormier E., Goepfert P.A., Borrow P., Robinson J.E., Gnanakaran S., Hunter E., Kong X.P., Derdeyn C.A. (2013). Viral escape from neutralizing antibodies in early subtype A HIV-1 infection drives an increase in autologous neutralization breadth. PLoS Pathogen 9(2): e1003173
  • Yosef N, Shalek AK, Gaublomme JT, Jin H, Lee Y, Awasthi A, Wu C, Karwacz K, Xiao S, Jorgolli M, Gennert D, Satija R, Shakya A, Lu DY, Trombetta JJ, Pillai MR , Ratcliffe PJ, Coleman ML , Bix M, Tantin D, Park H, Kuchroo VK, Regev A. Dynamic regulatory network controlling TH 17 cell differentiation. Nature. (2013) 25;496(7446):461-8.
  • Prashant Singh and NityaWadhwa, Mona K Chaturvedi, Vidyut Bhatia, SavitaSaini, Nikhil Tandon, Govind K Makharia, Markku Maki, Tarcisio Not, Alan Phillips, ShinjiniBhatnagar. (2014) Validation of point of care testing for Celiac Disease in children in a tertiary hospital in north India. Archives of Disease in Childhood (In press).
  • Dwivedi S, Das BK, Aneja S, Sharma S, Chaturvedi MK, Kahn G, Fitzwater SP, Chandran A, Wadhwa N, Bhatnagar S. (2014) Group B Streptococcal Meningitis in Infants Beyond the Neonatal Period. Indian J Pediatr;81(1):4-8. Epub 2013 Jul 24.
  • Wadhwa N, Chandran A, Aneja S, Lodha R, Kabra SK, Chaturvedi MK, Sodhi J, Fitzwater SP, Chandra J, Rath B, Kainth US , Saini S, Black RE , Santosham M, Bhatnagar S. (2013) Efficacy of zinc given as an adjunct in the treatment of severe and very severe pneumonia in hospitalized children 2-24 mo of age: a randomized, double-blind, placebo-controlled trial. Am J Clin Nutr; 97(6):1387-94
  • Ramachandran P, Fitzwater SP, Aneja S, Verghese VP, Kumar V, Nedunchelian K, Wadhwa N, Veeraraghavan B, Kumar R, Meeran M, Kapil A, Jasmine S, Kumar A, Suresh S, Bhatnagar S, Thomas K, Awasthi S, Santosham M, Chandran A. (2013) Prospective multi-centre sentinel surveillance for Haemophilus influenzae type b & other bacterial meningitis in Indian children. Indian J Med Res; 137(4):712-20.
  • Negi R1, Dewan P, Shah D, Das S, Bhatnagar S, Gupta P. (2014) Oral zinc supplements are ineffective for treating acute dehydrating diarrhoea in 5-12-year-olds. Acta Paediatr. Lodha R, Shah N, Mohari N, Mukherjee A, Vajpayee M, Singh R, Singla M, Saini S, Bhatnagar S, Kabra S. (2014) Immunologic effect of zinc supplementation in HIV infected children receiving highly active antiretroviral therapy: A randomized, double blind placebo controlled trial. J Acquir Immune DeficSyndr.1;66(4):386-92
  • Mukherjee A, Saini S, Kabra SK, Gupta N, Singh V, Singh S, Bhatnagar S, Saini D, Grewal HM , Lodha R1; Delhi TB Study group, Aneja S, Arya T, Bhatnagar S, Chandra J, Dutta A, Doherty T, Friis H, Grewal HM , Hesseling A, Kabra S, Lodha R, Marais B, Mukherjee A, Parashar D, Prajapati S, Purohit K, Saini D, Saini S, Singh RR , Singh S, Singh V. (2014) Effect of micronutrient deficiency on QuantiFER ON-TB Gold In-Tube test and tuberculin skin test in diagnosis of childhood intrathoracic tuberculosis. Eur J ClinNutr.68(1):38-42.
  • Natchu UCM ,Bhatnagar S. (2013) Diarrhoea in children: identifying the cause and burden. Lancet 2013;13: S0140-6736(13)60941-1
  • Singh P, Das P, Jain AK, Mathan M, Mathur M, Bhat AS , Varma S, Chaturvedi MK, Gupta SD, Bhatnagar S. (2013) Microscopic colitis in children with chronic diarrhea. J Pediatr Gastroenterol Nutr2013; 57(2):240-4
  • Tak V, Mirdha BR, Yadav P, Vyas P, Makharia GK, Bhatnagar S. (2014) Molecular characterisation of Giardia intestinalis assemblages from human isolates at a tertiary care centre of India. Indian J Med Microbiol.32(1):19-25.
  • Dwivedi S, Das BK, Aneja S, Sharma S, Chaturvedi MK, Kahn G, Fitzwater SP, Chandran A, Wadhwa N, Bhatnagar S. (2014) Group B Streptococcal Meningitis in Infants Beyond the Neonatal Period.Indian J Pediatr.81(1):4-8
  • Ramachandran P, Fitzwater SP, Aneja S, Verghese VP, Kumar V, Nedunchelian K, Wadhwa N, Veeraraghavan B, Kumar R, Meeran M, Kapil A, Jasmine S, Kumar A, Suresh S, Bhatnagar S, Thomas K, Awasthi S, Santosham M, Chandran A. (2013) Prospective multi-centre sentinel surveillance for Haemophilus influenzae type b & other bacterial meningitis in Indian children. Indian J Med Res. 137(4):712-20
  • Bhat AS , Chaturvedi MK, Saini S, Bhatnagar S, Gupta N, Sapra S, Gupta SD, Kabra M. (2013) Prevalenceof celiac disease in Indian children with Down syndrome and its clinical and laboratory predictors. Indian J Pediatr.80(2):114-7.
  • Sharma TK and Shukla R (2014).Nucleic acid aptamers as an emerging diagnostic tool for animal pathogens. A dvances in Animal and Veterinary Science 2 (1): 50 – 55.
  • Gosh IN, Patil SD, Sharma TK, Pathania R and Navani NK (2013). Synergestic action of cinnamaldehyde with silver nanoparticles against spore-forming bacteria: a case for judicious use of silver nanoparticles for antibacterial applications. International Journal of Nanomedicine 8 (1): 4721-4731.
  • Sharma TK and Shukla R (2014).Nanoscience and aptamer technology for point of care diagnostics. N anoscience and Technology 1 (2): 1-2 (Editorial)

Books

  • Ramakrishna B.S., N air G.B. and Takeda Y (Editors) 2014. Probiotics in Prevention of Life style Disorders. Published by Elsevier, Gurgaon, Haryana, India.

Abstracts published in conference proceedings

  • Role of mammalian RNAi in regulating dengue viral infection
    Pavan Kumar Kakumani, Guruprasad Medigeshi, Pawan Malhotra, Sunil Mukherjee, Raj Bhatnagar
    RNA Silencing, Keystone Sympoisa, March 19-24, 2013, Whistler Conference Center, Whistler, Canada.
  • Dengue Sero-epidemiology in Southern India: High prevalence of concurrent infection with multiple serotypes.
    Soham Gupta, Priyadarashini Kowtal, Ujjwal Neogi, Anmol Chandele, Guruprasad R. Medigeshi, Anita Shet
    Third International Conference on Dengue and Dengue Haemorrhagic Fever 2013 (Dengue 2013).
    21-23 October 2013, Bangkok, Thailand
  • Sankar Bhattacharyya, Utsav Sen and Sudhanshu Vrati. Japanese encephalitis virus infection: Riding on stress. 4th Annual conference of Indian Immunological Society, Nov 15-17, 2013. Immunocon, 2013 abstract book p13.

Publications

  • Appaiahgari MB and Vrati S. (2014) Adenoviruses as gene/vaccine delivery vectors: promises and pitfalls. Expert Opinion on Biological Therapy 15: 337-51.
  • Arora G, Sajid A, Singhal A, Joshi J, Virmani R, Gupta M, Verma N, Maji A, Misra R, Baronian G, Pandey A.K, Molle V, and Singh Y. (2014) Identification of Ser/Thr kinase and Forkhead Associated Domains in Mycobacterium ulcerans: Characterization of Novel Association between Protein Kinase Q and MupFHA. PloS Negl Trop Dis 8(11): e3315. doi; 10.1371/journal. pntd.0003315.
  • Arora G, Tiwari P, Mandal RS, Gupta A, Sharma D, Saha S and Singh R. (2014) High through put screen identifies small molecule inhibitors specific for Mycobacterium tuberculosis phosphoserine phosphatase. J Biol Chem 289(36): 25149-25165.
  • Bandopadhyay M, Banerjee A, Sarkar N, Panigrahi R, Datta S, Pal A, Singh SP, Biswas A, Chakrabarti S, Chakravarty R. (2014) Tumor suppressor micro RNA miR-145 and onco micro RNAs miR-21 and miR-222 expressions are differentially modulated by hepatitis B virus X protein in malignant hepatocytes. BMC Cancer 14:721-733.
  • Bansal S, Singh M, Kidwai S, Bhargava P, Singh A, Sreekanth V, Singh R and Bajaj A. (2014) Bile acid amphiphiles with tunable head groups as highly selective anti-tubercular agents. MS accepted in Med Chem Comm 5: 131-137.
  • Bhandari N, Rongsen-Chandola T, Bavdekar A, John J, Antony K, Taneja S, Goyal N, Kawade A, Kang G, Rathore SS, Juvekar S, Muliyil J, Arya A, Shaikh H, Abraham V, Vrati S, Proschan M, Kohberger R, Thiry G, Glass R, Greenberg HB, Curlin G, Mohan K, Harshavardhan GV, Prasad S, Rao TS, Boslego J, Bhan MK; Indian Rotavirus Vaccine Group. (2014) Efficacy of a monovalent human-bovine (116E) rotavirus vaccine in Indian children in the second year of life. Vaccine 32 Suppl 1 : A110-6.
  • Bhandari N, Rongsen-Chandola T, Bavdekar A, John J, Antony K, Taneja S, Goyal N, Kawade A, Kang G, Rathore SS, Juvekar S, Muliyil J, Arya A, Shaikh H, Abraham V, Vrati S, Proschan M, Kohberger R, Thiry G, Glass R, Greenberg HB, Curlin G, Mohan K, Harshavardhan GV, Prasad S, Rao TS, Boslego J, Bhan MK; Indian Rotavirus Vaccine Group. (2014) Efficacy of a monovalent human-bovine (116E) rotavirus vaccine in Indian infants: a randomised, double-blind, placebo-controlled trial. Lancet S0140-6736: 62630-6.
  • Bhullar D, Jalodia R, Kalia M, Vrati S. (2014) Cytoplasmic translocation of Polypyrimidine Tract-Binding Protein and Its Binding to Viral RNA during Japanese Encephalitis Virus Infection Inhibits Virus Replication PLos ONE 9(12): e114931. doi:10.1371/journal.pone.0114831.
  • Boliar S, Das S, Bansal M, Shukla BN, Patil S, Shrivastava T, Samal S, Goswami S, King CR, Bhattacharya J, Chakrabarti BK. (2015) An efficiently cleaved HIV-1 clade C Env selectively binds to neutralizing antibodies. PLoS ONE 10(3): e0122443.
  • Chauhan P, Reddy PV, Singh R, Jaisinghani N, Gandotra S and Tyagi AK. (2013) Secretory phosphatases deficient mutant of Mycobacterium tuberculosis imparts protection at the primary site of infection in guinea pigs. pLOS One 8 (10): e77930.
  • Choudhary E, Thakur P, Pareek M and Agarwal N (2015) Gene silencing by CRISPR interference in mycobacteria. Nat. Communications 6:6267 doi: 10.1038/ncomms7267.
  • Gupta M, Sajid A, Sharma K, Ghosh S, Arora G, Singh R, Nagaraja V, Tandon V and Singh Y. (2014) HupB, a nucleoid associated protein of Mycobacterium tuberculosis is modified by Serine/Threonine protein kinases in vivo. J Bacteriol 196: 2646-2657.
  • Gupta N, Hegde P, Lecerf M, Nain M, Kalia M, Vrati S, Bayry J, Lacroix-Desmazes S, Kaveri SV. (2014) Japanese encephalitis virus expands regulatory T cells by increasing the expression of PD-L1 on dendritic cells. European Journal of Immunology 44: 1363-74.
  • Kumar D, Beena, Khare G, Kidwai S, Tyagi AK, Singh R and Rawat DS. (2014) Synthesis of 1, 2, 3 triazole derivatives of isoniazid and their in vitro and in vivo anti-mycobacterial activity evaluation. Euro J Med Chem 81: 301 – 313.
  • Kumar D, Khare G, Beena, Kidwai S, Tyagi AK, Singh R and Rawat DS. (2015) Novel isoniazid-amidoether derivatives: synthesis, characterization and antimycobacterial activity evaluation. Med Chem Comm DOI: 10.10392015 (6) 131-137.
  • Kumar N, Kapoor E, Singh R, Kidwai S, Kumbukgolla W, Bhagat S and Rawat DS. (2013) Synthesis and antibacterial/antitubercular activity evaluation of symmetrical trans-cyclohexane-1,4-diamine derivatives. Ind J Chem 52B: 1441 – 1450.
  • Lakshinarayana SB, Boshoff HI, Cherian J, Ravindran S, GohA, Jiricek J, Nanjudappa M, Nayyar A, Gurumurthy M, Singh R, Dick T, Blasco F, Barry CE, Ho PC and Manjunatha UM. (2014) Pharmacokinetics-pharmacodynamics analysis of bicyclic -4-nitroimidazoles analogs in murine model of tuberculosis. PLOS One 9(8): e105222.
  • Maindola P, Raina R, Goyal P, Atmakuri K, Ojha A, Gupta S, Christie PJ, Iyer LM, Aravind L and Arockiasamy A. (2014) Multiple enzymatic activities of ParB/Srx superfamily mediate sexual conflict between among conjugative plasmids. Nat Commun 5: 5322. doi: 0.1038/ncomms6322.
  • Pareek S, Roy S, Kumari B, Jain P, Banerjee A, Vrati S. (2014) miR-155 induction in microglial cells suppresses Japanese encephalitis virus replication and negatively modulates innate immune responses. J Neuroinflammation 11:97-110.
  • Patil S, Choudhary I, Chaudhary NK, Ringe R, Bansal M, Shukla BN, Boliar S, Chakrabarti B K, Bhattacharya J. (2014) Determinants in V2C2 region of HIV-1 clade C primary envelopes conferred altered neutralization susceptibilities to IgGb12 and PG9 monoclonal antibodies in a context-dependent manner. Virology, 462-463C: 266-272.
  • Sarkar N, Panigrahi R, Pal A, Biswas A, Singh SP, Kar S, Bandopadhyay M, Das D, Saha D, Kanda T, Sugiyama M, Chakrabarti S, Banerjee A, Chakravarty R (2015). Expression of microRNA-155 correlates positively with the expression of Toll Like Receptor 7 and modulates Hepatitis B Virus via C/EBP-β in Hepatocytes. J Viral Hepatitis (in press).
  • Sharma D, Priyadarshini P and Vrati S. (2015) Unravelling the web of viroinformatics: computational tools and databases in viral research. Journal of Virology 89: 1489-501.
  • Sharma M, Bhattacharya S, Nain M, Kaur M, Sood V, Gupta V, Khasa R, Abdin MZ, Vrati S, Kalia M. (2014) Japanese encephalitis virus replication is negatively regulated by autophagy and occurs on LC3-I and EDEM1 containing membranes. Autophagy 10: 1637-51.
  • Singh R, Singh M, Arora G, Kumar S, Tiwari P, Kidwai S. (2013) Polyphosphate deficiency in mycobacterium tuberculosis is associated with enhanced drug susceptibility and impaired growth in guinea pigs. J Bacteriol 195: 2839 – 51.
  • Tiwari P, Arora G, Singh M, Kidwai S, Narayan O and Singh R. (2015). MazF ribonucleases promote Mycobacterium tuberculosis drug tolerance and virulence in guinea pigs. MS accepted in Nature Communications 6:6059 doi 10.1038/ncomms 7059.
  • Wen Y, Lin X, Fan B, Ranjith-Kumar CT, Kao CC. (2015) The juxtamembrane sequence of the Hepatitis C virus polymerase can affect RNA synthesis and inhibition by allosteric polymerase inhibitors. Virus Genes 51(1): 1-11. Lodha R, Mukherjee A, Singh V, Singh S, Friis H, Faurholt-Jepsen D, Bhatnagar S, Saini S, Kabra SK, Grewal MH (2014) Delhi Pediatric TB Study Group. Effect of micronutrient supplementation on treatment outcomes in children with intrathoracic tuberculosis: a randomized controlled trial. Am J Clin Nutr 100(5): 1287-97.
  • Lodha R, Shah N, Mohari N, Mukherjee A, Vajpayee M, Singh R, Singla M, Saini S, Bhatnagar S, Kabra S. (2014) Immunologic effect of zinc supplementation in HIV infected children receiving highly active antiretroviral therapy: A randomized, double blind placebo controlled trial. J Acquir Immune Defic Syndr 66(4):386-92.
  • Mukherjee A, Saini S, Kabra SK, Gupta N, Singh V, Singh S, Bhatnagar S, Saini D, Grewal HM, Lodha R; Delhi TB Study group. (2014) Effect of micronutrient deficiency on QuantiFERON-TB Gold In-Tube test and tuberculin skin test in diagnosis of childhood intrathoracic tuberculosis. Eur J Clin Nutr 68(1):38-42.
  • Negi R, Dewan P, Shah D, Das S, Bhatnagar S, Gupta P. (2014) Oral zinc supplements are ineffective for treating acute dehydrating diarrhoea in 5-12-year-olds. Acta Paediatr 104(8): e367-71.
  • Prasad K, Sharma A, Garg A, Mohanty S, Bhatnagar S, Johri S, Singh KK, Nair V, Sarkar RS, Gorthi SP, Hassan KM, Prabhakar S, Marwaha N, Khandelwal N, Misra UK, Kalita J, Nityanand S; for InveST Study Group. (2014) Intravenous autologous bone marrow mononuclear stem cell therapy for ischemic stroke: a multicentric, randomized trial. Stroke 45(12): 3618-24.
  • Rathore DK, Nair D, Raza S, Saini S, Singh R, Kumar A, Tripathi R, Ramji S, Batra A, Aggarwal KC, Chellani HK, Arya S, Bhatla N, Paul VK, Aggarwal R, Agarwal N, Mehta U, Sopory S, Natchu UCM, Bhatnagar S, Bal V, Rath S, Wadhwa N. (2015) Underweight full-term Indian neonates show differences in umbilical cord blood leukocyte phenotype. PLoS ONE 10(4): e0123589.
  • Singh P, Wadhwa N , Lodha R, Sommerfelt H, Aneja S, Natchu UCM, Kabra SK, Bhatnagar S, Strand TA. (2015) Predictors of time till recovery in infants with probable serious bacterial infections. PLoS ONE 10(4): e0124594.
  • Singh P, Wadhwa N, Chaturvedi MK, Bhatia V, Saini S, Tandon N, Makharia GK, Maki M, Not T, Phillips A, Bhatnagar S. (2014) Validation of point-of-care testing for coeliac disease in children in a tertiary hospital in north India. Arch Dis Child 99(11):1004-8.Chopra, A.; Shukla, R.; Sharma, T. K. (2014) Aptamers as an emerging player in Biology. Aptamers and Synthetic Antibodies, 1(1): 1-11.
  • Ghosh IN, Sharma TK, Shrivastava SK, Pathania R, Navani NK. (2013) Synergistic action of cinnamaldehyde with silver nanoparticles against spore-forming bacteria: a case for judicious use of silver nanoparticles for antibacterial applications. International Journal of Nanomedicine, 8: 4721-4731.
  • Kulshreshtha P, Tiwari A, Priyanka, Joon S, Sinha S, Bhatnagar R. (2015) Investigation of a panel of monoclonal antibodies and polyclonal sera against anthrax toxins resulted in identification of an anti-lethal factor antibody with disease-enhancing characteristics. Mol Immunol (in press).
  • Sharma C, Sankhyan A, Sharma T, Khan N, Chaudhuri S, Kumar N, Bhatnagar S, Khanna N, Tiwari A. (2015) A repertoire of high-affinity monoclonal antibodies specific to S. typhi: as potential candidate for improved typhoid diagnostic. Immunol Res 62(3): 325-40.
  • Sharma TK, Ramanathan R, Mohammadtaheri, M, Daima HK, Shukla R, Bansal V. (2014) Aptamer-mediated ‘turn-off/turn-on’ nanozyme activity of gold nanoparticles for kanamycin detection. Chemical Communications, 50: 15856-15859.
  • Sharma TK, Ramanathan R, Rakwal R, Agrawal GK, Bansal V. (2015) Moving forward in plant food safety and security through NanoBioSensors: Adopt or adapt biomedical technologies? Journal of Proteomics 15:1680-1692.
  • Sharma TK, Shukla R. (2014) Editorial: Nanoscience and Aptamer Technology for Point of Care Diagnostics. Nanoscience and Technology 1:1-2.
  • Sharma TK, Shukla R. (2014) Nucleic acid aptamers as an emerging diagnostic tool for animal pathogens. Advances in Animal and Veterinary Sciences, 2: 50-55.
  • Weerathunge P, Ramanathan R, Shukla R, *Sharma TK, Bansal V. (2014) Aptamer-controlled reversible inhibition of gold nanozyme activity for pesticide sensing. Analytical Chemistry, 86: 11937–11941.
  • Kumar R, Sharma YP, Thakur JS, Patro BK, Bhatia A, Singh IP, Rana SK, Chakraborti A, Dhanda V, Sapru S, Sharma M, Shah B, Ganguly NK. (2014) Streptococcal pharyngitis, rheumatic fever and rheumatic heart disease: Eight-year prospective surveillance in Rupnagar district of Punjab, India. Natl Med J India, 27(2):70-5.
  • Ganguly NK, Croft S, Singh L, Sinha S, Balganesh T. (2014) Biomedicine and biotechnology: public health impact. Biomed Res Int.
  • Lagrange PH, Thangaraj SK, Dayal R, Deshpande A, Ganguly NK, Girardi E, Joshi B, Katoch K, Katoch VM, Kumar M, Lakshmi V, Leportier M, Longuet C, Malladi SV, Mukerjee D, Nair D, Raja A, Raman B, Rodrigues C, Sharma P, Singh A, Singh S, Sodha A, Kabeer BS, Vernet G, Goletti D. (2014) A toolbox for tuberculosis (TB) diagnosis: an Indian multi-centric study (2006-2008); evaluation of serological assays based on PGL-Tb1 and ESAT-6/ CFP10 antigens for TB diagnosis. PLoS One, 9(5).
  • Mukhopadhyay B, Ganguly NK. (2014) The Unexplored Role of Probiotics on the Parasitic Pathogens. Food and Nutrition Sciences, No. 22, 2177-2184.
  • Mukhopadhyay B, Ganguly NK. (2014) The Unexplored Effect of Probiotics on Protozoan Parasite. Probiotic Association of India Newsletter, Vol. 1, Iss. 6.
  • Hajela N, Nair GB, Ramakrishna BS, Ganguly NK. (2014) Probiotic foods: can their increasing use in India ameliorate the burden of chronic lifestyle disorders? Indian J Med Res., 139(1): 19-26. Review.
  • G-FINDER Report - 2014 Neglected disease research and development: Emerging trends - (Dr. Gautam Kumar Saha)
  • The G-FINDER Report 2013: Neglected disease research and development: The public divide (Dr. Gautam Kumar Saha)
  • Lagrange PH, Thangaraj SK, Dayal R, Deshpande A, Ganguly NK, Girardi E, Joshi B, Katoch K, Katoch VM, Kumar M, Lakshmi V, Leportier M, Longuet C, Malladi SV, Mukerjee D, Nair D, Raja A, Raman B, Rodrigues C, Sharma P, Singh A, Singh S, Sodha A, Kabeer BS, Vernet G, Goletti D. (2013) A toolbox for tuberculosis (TB) diagnosis: an Indian multicentric study : Evaluation of QuantiFERON-TB gold in tube for TB diagnosis. PLoS One, 8(9): e73579. doi: 10.1371/journal.pone.0073579. eCollection.
  • Gupta SS, Nair GB, Arora NK, Ganguly NK. (2013) Vaccine development and deployment: opportunities and challenges in India. Vaccine, 31 Suppl 2:B43-53, Review.
  • Bharati K, Ganguly NK. (2013) Tackling the malaria problem in the South-East Asia Region: need for a change in policy? Indian J Med Res, 137(1): 36-4.
  • Bharati K, Ganguly NK. (2013) Does India need an indigenous HPV vaccine and why? J Public Health Policy, 34(2): 272-87. doi: 10.1057/jphp.2013.4. Epub.
  • Mukhopadhyay B, Ganguly NK. (2013) Tuberculosis research in India. Curr. Sci, 105(5): 594-596.
  • Singh V, Kaur C, Chaudhary VK, Rao K, Chatterjee S. (2014) M. tuberculosis Secretory Protein ESAT-6 Induces Metabolic Flux Perturbations to Drive Foamy Macrophage Differentiation. Scientific Reports. (in press).
  • Chatterjee S, Pessani D, Venturino E. (2015) Harvesting strategies for “bianchetti” and “blue fish” in the Ligurian Sea (North Mediterranean). Appl. Math. Infortn Scis. (in press).
  • Pedruzzi G, Rao K, Chatterjee S. (2015). Mathematical model of mycobacterium-host interaction describes physiology of persistence. Journal of Theoretical Biology 376: 105-117.
  • Biswas S, Chatterjee S, Chattopadhyay J. (2015). Cannibalism may control disease in predator population: Result drawn from a model based study. Mathematical methods in the Applied Sciences 38: 2272-2290.
  • Sinha N, Negi S, Tikoo K, Sharma S, Tripathi P, Kumar D, Rao KVS, Chatterjee S. (2014). Molecular signatures for obesity and associated disorders identified through partial least square regression models. BMC System Biology 8:104.
  • Mehrotra P, Jamwal S, Saquib N Md, Sinha N, Siddiqui Z, Manivel V, Chatterjee S, Rao KVS. (2014). Pathogenicity of Mycobacterium tuberculosis is expressed by regulating metabolic thresholds of the host macrophage. PLOS Pathogens 10 (7): e1004265. doi: 10.1371/journal. ppat.1004265.
  • Mehta J, Asthana S, Mandal CC, Saxena S. (2015) A molecular analysis provides novel insights into androgen receptor signaling in breast cancer. PLoS One. 17; 10(3).
  • Asthana S, Shukla S, Ruggerone P, Vargiu AV. (2014) Molecular mechanism of viral resistance to a potent non-nucleoside inhibitor unveiled by molecular simulations. Biochemistry 11:6941-53.
  • Caboni P, Liori B, Kumar A, Santoru ML, Asthana S, Pieroni E, Fais A, Era B, Cacace E, Ruggiero V, Atzori L. (2014) Metabolomics analysis and modeling suggest a lysophosphocholines-PAF receptor interaction in fibromyalgia. PLoS One. 19; 9 (9).
  • Bag S, Das B, Dasgupta S, Bhadra RK. (2014) Mutational analysis of the (p) ppGpp synthetase activity of the Rel enzyme of Mycobacterium tuberculosis. Arch Microbiol 196(8): 575-88.
  • Barman S, Koley H, Nag D, Shinoda S, Nair GB, Takeda Y. (2014) Passive immunity with multi-serotype heat-killed Shigellae in neonatal mice. Microbiology and Immunology. 58(8): 463-6.
  • Das B. (2014) Mechanistic insights into filamentous phage integration in Vibrio cholerae. Front. Microbiol. 5:650. DOI: 10.3389/fmicb.2014.00650.
  • Das B, Banerjee R, Nair GB, Basak S. (2014) Dynamics in genome evolution of Vibrio cholerae. Infect Genet Evol 23: 32-41.
  • Das B, Kumari R, Pant A, Sen Gupta S, Saxena S, Nair GB. (2014) A Novel, Broad-Range, CTXΦ -Derived Stable Integrative Expression Vector For Functional Studies. J. Bacteriol 196(23): 4071-80.
  • Das B, Midonet C, Paly E, Barre FX. (2014) XerD initiates the integration of TLCΦ into the Vibrio cholerae genome independently of FtsK. Proc Natl Acad Sci USA 111 (47): 16848-16853.
  • Das B, Nair GB, Bhadra RK. (2014) Acquisition and dissemination mechanisms of CTXΦ in Vibrio cholerae: New paradigm for diff residents. World J Med Genet 4: 27-33.
  • Ghosh TS, Sen Gupta S, Bhattacharya T, Yadav D, Barik A, Chowdhury A, Das B, Mande SS, Nair GB. (2014) Gut Microbiomes of Indian children of varying nutritional status. PLoS One 9: e95547.
  • Hajela N, Ramakrishna BS, Nair GB, Abraham P, Gopalan S, Ganguly NK. (2015) Gut microbiome, gut function, and probiotics: Implications for health. Indian J Gastroenterol. 34(2): 93-107.
  • Kanungo S, Lopez AL, Ali M, Manna B, Kim DR, Mahapatra T, Holmgren J, Dhingra MS, Weirzba TF, Nair GB, Bhattacharya SK, Clemens JD, Sur D. (2014) Vibriocidal antibody responses to a bivalent killed whole-cell oral cholera vaccine in a phase III trial in Kolkata, India. PLoS One. 9(5): e96499.
  • Kanungo S, Sen B, Ramamurthy T, Sur D, Manna B, Pazhani GP, Chowdhury G, Jhunjhunwala P, Nandy RK, Koley H, Bhattacharya MK, Gupta S, Goel G, Dey B, M T, Nair GB, Ghosh A, Mahalanabis D. (2014). Safety and immunogenicity of a live oral recombinant cholera vaccine VA1.4: a randomized, placebo controlled trial in healthy adults in a cholera endemic area in Kolkata, India. PLoS One. 9(7): e99381
  • Kim EJ, Lee D, Moon SH, Lee CH, Kim SJ, Lee JH, Kim JO, Song M, Das B, Clemens J, Pape JW, Nair GB, Kim DW. (2014) Molecular insights into the evolutionary pathway of Vibrio cholerae O1 atypical El Tor variants. PLoS Pathogens 0(9): e1004384.
  • Kim JE, Lee HC, Nair GB, Kim WD. (2015) Whole-genome sequence comparisons reveal the evolution of Vibrio cholera O1. Trends in Microbiology. Apr 23. 1-11.
  • Lopez AL, Gonzales ML, Aldaba JG, Nair GB. (2014) Killed oral cholera vaccines: history, development and implementation challenges. Ther Adv Vaccines. 2(5):123-36.
  • Malik S, Muzamil Want, Awasthi A. (2015) Emerging role of gamma-delta T cells in tissue inflammation in EAE. Frontiers of Immunology 2015 (in press)
  • Tyagi RK, Garg NK, Jadon R, Sahu T, Karare OP, Awasthi A, Marepally SK. (2015) Elastic liposome mediated transdermal immunization enhanced the immunogenicity of P. falciparum surface antigen, MSP-1. Vaccine (in press)
  • Yamasaki E, Yamada C, Jin X, Nair GB, Kurazono H, Yamamoto S. (2015) Expression of marA is remarkably increased from the early stage of development of fluoroquinolone-resistance in uropathogenic Escherichia coli. Journal of Infection and Chemotherapy. 21(2): 105-9.

Patents

  • Cleaved functional clade C envelope glycoprotein: U.S. provisional patent application Serial No. 62/068,202
  • Native trimeric ENV immunogen design: U.S. Patent Application No.62,155,673
  • HIV-1 CLADE C ENVELOPE GLYCOPROTEINS: US provisional application. 62/189,418.
  • 7-substituted 2-nitro 6,7- dihydroimidazo [2,1-b][1,3] oxazine derivatives of their optical isomers, pharmaceutical composition containing the same as an active ingredient. Korean application no. DP-201-40911-01.
  • Technology for ELISA kits for rapid diagnosis of celiac diagnosis were transferred to J. Mitra and Co and were commercialised in October 2014
  • Bhatnagar S, Khanna N, Natchu UCM, Wadhwa N, Gupta S, Bagga A, Saini S. “A method and device for detection of anti-transglutaminase antibodies” (patent no. 1133/DEL/2011 dated 18-04-2011).
  • Production of recombinant ATB protein and its uses as diagnostic tool thereof - 1350/DEL/2015
  • Monoclonal Antibodies specific to Salmonella typhi flagellin, and use thereof - 683/DEL/2015
  • Human monoclonal antibodies specific to preS1 domain of Hepatitis B virus, and use thereof 2291/DEL/2015
  • Drug Targeting: Rajat Anand, Srikanth Ravichandran, Samrat Chatterjee. 78/DEL/2015
  • Computer Software for Drug Targeting: Rajat Anand, Samrat Chatterjeee. 52951/2014-CO/SW (Indian, copyright application)
  • Novel Autophagy-inducing Compounds: Singh. 1055/DEL/2014 (Indian application)
  • Compounds for Induction of Autophagy: Singh. 1056/DEL/2014 (Indian application)
  • Novel Compounds as anti-Tubercular Agents: Sundeep Dugar, Dinesh Mahajan, Kanury Rao, Varshneya Singh. 1431/DEL/2014 (Indian Application)