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People : Scientific : Faculty & Scientists

DR. MADHU DIKSHIT, FNA, FNASc, FASc, JC Bose National Fellow 

Thsti National Chair
+91-129-2876448 
madhudikshit [at] thsti [dot] res [dot] in
MSc in biochemistry from Allahabad University, Allahabad
PhD in Pharmacology, CDRI, Lucknow

Professional Affiliations:      

Society memberships

  • Indian Society of Free Radical Research
  • International Society of Heart Research (Indian section)
  • Indian Pharmacological Society
  • Society of Biological Chemists
  • Indian Academy of Neurosciences, India
  • UP association of Science and Technology
  • National Academy of Sciences, India
  • Indian Academy of Sciences
  • National Academy of Medical Sciences, India.
  • The Cytometry Society of India
  • Indian Society for Atherosclerosis Research
  • Pulmonary Vascular Research Ins, India

Committee memberships

  • Chair-person, Research Advisory Committee at KGMU, Lucknow (2018)
  • Member Genetic Engineering Appraisal Committee (GEAC, 2018-2020).
  • Member GB National Institute of Plant Genome Research, New Delhi (2017-2020)
  • Member, GB CBMR, Lucknow (2017-till present).
  • Member, Council of Indian National Academy of Sciences (2017-2019).
  • Member, Research Council, Indian Institute Chemical Biology, Kolkata, 2017.
  • Member of Expert Committee on “Exploration, Discovery and Utilization of biological resources for sustainable development in Northeast India” 2017
  • Member, Steering Committee of NIPERs, Department of Pharmaceuticals, Ministry of Chemicals & Fertilizers, GoI, 2017
  • Member, Council of Indian Academy of Sciences (2016-2018).
  • Member, Scientific Advisory Committee (SAC), DBT-IISc Partnership Programme (2016-2018).
  • Core Member, Programme Advisory Committee on Health Sciences, SERB, DST (2016-till present).
  • Member, Academic Council, Jawaharlal Nehru University, New Delhi (2016)
  • Member SUNPHARMA Research Foundation Board, 2016.
  • Member of the expert committee of DBT to review Bangalore Life Science Cluster (B-LIFE) 2017.
  • Member, Human Ethics Committee CBMR, Lucknow (2016-till present).
  • Member, Sectional Committee, The National Academy Science, India.
  • Member, National Research Advisory Committee Meeting of National Innovation Foundation- India, Ahmedabad (2016-2017).
  • Member, Indian Council of Medical Research (Medical Sciences) PAC (2014-till present).
  • Member, Drug Technical Advisory Board, Directorate General of Health Services, DCGI, India (2016-2018).
  • Member, Council of Scientific Industrial Research (Organic & Medicinal Chemistry and Chemical Technology Res Committee).
  • Member, Institute Body of Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow 2015-2018.
  • Member, Human ethics committee CBMR, Lucknow (2011-2013)
  • Member, Expert Committee on Malaria Diagnostic and Chemotherapy and Prospects of Malaria Elimination in the Country.
  • Member, Advisory-cum-Monitoring Committee of Biotech Park, Lucknow 2015-17.
  • Member, Organic Chemicals, Alcohols & Allied Products Sectional Committee, PCD 09, Bureau of Indian Standards, New Delhi.
  • Member, Academic Standards Committee, NIPER.
  • Member, Sectional Committee (Health Sciences), Indian National Science Academy
  • Member, Sectional Committee (Biological Sciences) National Academy of Sciences India
  • Member Sectional Committee Indian Academy of Science
  • Member, Lucknow Management Association.
  • Member General Body CSIR.
  • Member of committee on Consultation on evaluation of NIPERs.
  • Committee to review the functioning of the Research Councils of Ministry of Ayush.
  • Member, Human ethics committee KGMU, Lucknow (2011-2013)
  • Member, RCGM, DBT New Delhi (2012-2014)
  • Chair-person, Human Ethics Committee KGMU, Lucknow (2017-2018).

Member Editorial Boards

  • Annals of Neurosciences
  • Drugs and Pharmaceuticals Industry Highlights
  • Guest Editor Cell Mol Biol 53, 2007
  • Proceedings of the National Academy of Sciences
  • Cytometry Part A, Wiley-Blackwell
  • Indian Journal of Pharmacology
  • Redox Biology,Elsevier

 

Honors And Awards

  • THSTI National Chair, 2018
  • Prof. N.R. Dhar Memorial Lecture Award, NASI, 2017
  • AstraZenecaOration Award,NIPER Mohali, 2017
  • GJS Rao Memorial lecture, at Biochemistry Department Indian Institute of Sciences, 2014
  • VASVIK Award-2012in the category of Smt. Chandaben Mohanbhai Patel Industrial Research Award for Women Scientists, awarded in 2014.
  • Professor Darshan Ranganathan Memorial Lectureof the Indian National Science Academy, 2013.
  • Vigyan Ratnaof Council of Science & Technology UP, 2010.
  • Dr. N. S. Dhalla Oration, of Indian Pharmacological Society for contribution in Cardiovascular Sciences, 2006.
  • National Bioscience Award, by the Department of Biotechnology, Ministry of Science & Technology for 2000.
  • Invited Senior Scientist Position award by French Ministrere de la Recherché for three months (1st Oct to 31st Dec, 2000), at a CNRS, Lab Faculty of Medicine Nancy, France.
  • Professor K.P. Bhargava Memorial Medalfrom Indian National Science Academy, New Delhi, India for 1999.
  • Uvnas Prizeof Indian Pharmacological Society (two times) for the best-published papers, for 1995 and for 1996.
  • Shakuntala Amir Chand Prizeof Indian Council of Medical Research for 1994.
  • Young Scientist Award(Medical Sciences) of Indian National Science Academy for 1989.

 

  • Pandey CP, Misra A, Negi MPS, Kanuri  BN,ChhonkerYS,Bhatta RS, Narain VS,Dikshit  M. Cytochrome P450, P2Y12, COX1 and GPVI gene polymorphisms and responsiveness towards dual anti-platelet therapy in MI patients. Ind J Med Res (in press), 2018.
  • Anthelme SN-A, Pathak P, Kanshana JS, Kanuri BN, Rebello SC, Kumar B, Yadav PP, Traore F, Jagavelu K, Dikshit M. Vasomodulatory effects and mass spectral analysis of Bridelia ferruginea Benth. Ind J Exp Biol, 2018.
  • Kanuri BN, Rebello SC, Pathak P, Agarwal H, Kanshana JS, Awasthi D, Gupta AP, Gayen JR, Jagavelu K, Dikshit M. Glucose and lipid metabolism alterations in liver and adipose tissue pre-dispose p47phox knockout mice to systemic insulin resistance. Free Rad Res.52, 568-582, 2018.
  • Misra A, Prakash P, Aggarwal H, Dhankani P, Kumar S, Pandey CP, Pugh N, Bihan D, Barthwal MK, Farndale RW, Dikshit DK, Dikshit M. Anti-thrombotic efficacy of S007-867: pre-clinical evaluation in experimental models of thrombosis in vivo and in vitro. Biochem Pharmacol. 148: 288-297, 2018.
  • Nagarkoti S, Dubey M, Awasthi D, Kumar V, Chandra T, Kumar S, Dikshit M. S-Glutathionylation of p47phoxsustains superoxide generation in activated neutrophils. BBA Mol Cell Res 1865: 444-454, 2018.
  • Kanshana JS, Rebello SC, Pathak P, Kanuri BN, Aggarwal H, Srivastava V, Khanna V, Singh V, Jagavelu K, Barthwal MK, Dikshit M. Standardized fraction of Xylocarpus moluccensis fruits improve vascular relaxation and plaque stability in dyslipidemic models of atherosclerosis. J Ethnopharmacol., 213: 81-91, 2018.
  • Gupta A, Beg M, Kumar D, Shankar K, Varshney S, Rajan S, Srivastava A, Singh K, Sonkar S, Mahdi AA, Dikshit M, Gaikwad AN. Chronic hyper-leptinemia induces insulin signaling disruption in adipocytes: Implications of NOS2. Free Rad Biol Med. 112:93-108, 2017.
  • Jain M, Kumar A, Singh US, Kushwaha R, Singh AK, Dikshit M, Tripathi AK. Cellular and plasma nitrite levels in myeloid leukemia: a pathogenetic decrease. Biol Chem. 398:1259-1265, 2017.
  • Kanuri BN, Kanshana JS, Rebello SC, Pathak P, Gupta AP, Gayen JR, Jagavelu K, Dikshit M. Altered glucose and lipid homeostasis in liver and adipose tissue pre-dispose inducible NOS knockout mice to insulin resistance. Sci Rep 41009, 2017.
  • Khanna V, Kanshana JS, Singh V, Jain M, Misra A, Farooqui M, Barthwal MK, Dikshit M. Time dependent characterization of accelerated atherosclerosis in iliac artery of New Zealand White rabbits.J Cardiovasc Pharmacol. 69: 314-325, 2017.
  • Saha P, Yeoh BS, Olvera RA, Xiao X, Singh V, Awasthi D, Subramanian BC, Chen Q, Dikshit M, Wang Y, Parent CA, Vijay-Kumar M.Bacterial siderophores hijack neutrophil functions. J Immunol. 198: 4293-4303, 2017. 
  • Bhunia SS, Misra A, Khan IA, Gaur S, Jain M, Singh S, Saxena A, Hohlfield T, Dikshit M, Saxena AK. Novel Glycoprotein VI Antagonists as antithrombotics: Synthesis, Biological evaluation, and molecular modeling studies on 2,3-disubstituted tetrahydropyrido(3,4-b)indoles. J Med Chem. 60:322-337, 2017.
  • Dubey M, Nagarkoti S, Awasthi D, Singh AK, Chandra T, Kumaravelu J, Barthwal MK, Dikshit M. Nitric oxide mediated apoptosis of neutrophils through caspase-8 and caspase-3 dependent mechanism. Cell Death Disease 7: e2348, 2016.
  • Singh AK, Awasthi D, Dubey M, Nagarkoti S, Trivedi AK, Kumar A, Chandra T, Barthwal MK, Tripathi AK, Dikshit M. High oxidative stress adversely affects NFκB mediated induction of inducible nitric oxide synthase in human neutrophils: Implications in chronic myeloid leukemia. NO Biol Chem.58: 28-41, 2016.
  • Rana M, Maurya P, Reddy SS, Singh V, Ahmad H, Dwivedi AK, Dikshit M, Barthwal MK. A standardized chemically modified curcuma longa extract modulates IRAK-MAPK signaling in inflammation and potentiates cytotoxicity. Front Pharmacol, 7: 1-14, 2016.
  • Rana M, A Kumar, RL Tiwari, V Singh, T Chandra, Dikshit M, MK Barthwal. IRAK regulates macrophage foam cell formation by modulating genes involved in cholesterol uptake and efflux. Bioessays, 38: 591-604, 2016.
  • Manhas A, Tripathi D, Biswas B, Ahmad H, Goyal D, Dwivedi, AK, Dikshit M,  Kumaravelu J. Non-carbonyl Curcuma longa [NCCL] protects the heart from myocardial ischemia/reperfusion injury by reducing endothelial microparticle mediated inflammation in rats. RSC Adavnces 6: 54938-54948, 2016.
  • Singh V, San Yeoh B, Chassaing B, Zhang B, Saha P, Xiao X, Awasthi D, Shashidharamurthy R, Dikshit M, Gewirtz A, Matam VK. Microbiota-inducible innate immune siderophore binding protein lipocalin 2 is critical for intestinal homeostasis. Cell Mol Gastroenterol Hepatol. 2: 482-498, 2016.
  • Misra A, Kumar KSA, Jain M, Bajaj K, Shindya S, Srivastava S, Shukla P, Barthwal MK, Dikshit M, Dikshit DK, Synthesis and evaluation of dual antiplatelet activity of bispidine derivatives of N-substituted pyroglutamic acids, Eur J Med Chem, 110: 1-12, 2016.
  • Awasthi D, Nagarkoti S, Kumar A, Dubey M, Singh AK, Pathak P, Chandra T, Barthwal MK, Dikshit M. Oxidised LDL induced extracellular trap formation in human neutrophils via TLR-PKC-IRAK-MAPK and NADPH-oxidase activation. Free Rad Biol Med, 93: 190-203, 2016.
  • Chhonker YS, Pandey CP, Chandasana H, Laxman TS, Prasad YD, Narain VS, Dikshit M, Bhatta RS. Simultaneous quantitation of acetylsalicylic acid and clopidogrel along with their metabolites in human plasma using liquid chromatography tandem mass spectrometry, Biomed Chromatogr. 30: 466-473, 2016.
  • Singh A, Singh V, Tiwari RL, Chandra T, Kumar A, Dikshit M, Barthwal MK. The IRAK-ERK-p67phox-Nox-2 axis mediates TLR4, 2-induced ROS production for IL-1β transcription and processing in monocytes. Cell Mol Immunol. 13: 745-763. 2016.
  • Singh V, Rana M, Jain M, Singh N, Naqvi A, Malasoni R, Dwivedi AK, Dikshit M, Barthwal MK. Curcuma oil attenuates accelerated atherosclerosis and macrophage foam-cell formation by modulating genes involved in plaque stability, lipid homeostasis and inflammation. Br J Nutr.113: 100-113. 2015.
  • Dubey M, Singh AK, Awasthi D, Nagarkoti S, Kumar V, Kumar S, Sánchez FJ, Ali W, Chandra T, Barthwal MK, Jagavelu K, Lamas S and Dikshit M. L-Plastin S-glutathionylation promotes reduced binding to β-actin and affects neutrophil functions. Free Rad Biol Med 86: 1-15, 2015.
  • Rana M, Reddy SS, Maurya P, Singh V, Chaturvedi S, Kaur K, Agarwal H, Ahmad H, Naqvi A, Dwivedi AK, Dikshit M, Barthwal MK. Turmerone enriched standardized curcuma longa extract alleviates LPS induced inflammation and cytokine production by regulating TLR4-IRAK1-ROS-MAPK-NFkB axis. J Functional Foods16: 152-163, 2015.
  • Dighe SU, Kumar KSA, Srivastava S, Shukla P, Singh S, Dikshit M, Batra S. Regioselective metal-free decarboxylative multicomponent coupling of proline, aldehydes and isonitriles leading to n-substituted prolinamides with antithrombotic activity. J Org Chem. 80: 99-108, 2015.
  • Singh V, Jain M, Misra A, Khanna V, Prakash P, Malasoni R, Dwivedi AK, Dikshit M, Barthwal MK. Curcuma oil ameliorates insulin resistance and associated thrombotic complications in hamster and rat. Ind J Med Res, 141: 823-832, 2015.
  • Singh M, Singh KP, Shukla S, Dikshit M. Assessment of in utero venlafaxine induced, ROS-mediated, apoptotic neurodegeneration in fetal neocortex and neurobehavioral sequelae in rat offspring. Int J Dev Neurosci, 40: 60-69, 2015.
  • Manhas A, Khanna V, Prakash P, Goyal D, Malasoni R, Naqvi A, Dwivedi A, Dikshit M, Jagavelu KJ. Curcuma oil reduces endothelial cell mediated inflammation in post myocardial ischemia /reperfusion in rats.JCardiovasc Pharmacol. 64: 228-236, 2014.
  • Tiwari RL, Singh V, Singh A, Rana M, Verma A, Kothari N, Kohli M, Bogra J,Dikshit M, Barthwal MK. PKCδ-IRAK1 axis regulates oxidized LDL induced IL-1β production in monocytes.J Lipid Res. 55: 1226-1244, 2014.
  • Singh S, Sharma S, Nath C, Rath SK, Singh RK, Bhadauria S, Singh P, Shukla RK, Barthwal MK, Dikshit M. Essential Safety Pharmacology and safety evaluation of bioactive fraction of Xylocarpus moluccensis: an anti-dyslipidaemic agent. Inter. J Med Sci Clin Invention1: 24-47, 2014.
  • Garikipati VNS, Jadhav S, Pal P, Prakash P, Dikshit M, Nityanand S. Mesenchymal stem cells from fetal heart attenuate myocardial injury after infarction: An in vivo serial pinhole gated SPECT-CT study in rats. PLOS One9: e100982, 2014.
  • Kumar AKS, Misra A, Siddiqui TI, Srivastava S, Jain M, Bhatta RS, Dikshit M, Dikshit DK. Synthesis and identification of chiral amino methyl piperidine carboxamides as inhibitor of collagen induced platelet activation. Eur J Med Chem. 81: 456-472, 2014.
  • Prakash P, Singh V, Jain M, Rana M, Khanna V, Barthwal MK, Dikshit M: Silymarin ameliorates fructose induced insulin resistance syndrome by reducing de novo hepatic lipogenesis in rat. Eur J Pharmacol.727: 15-28, 2014.
  • Jyoti A, Singh A, Dubey M, Kumar S, Saluja R, Keshari R, Verma A, Chandra T, Kumar A, Bajpai V, Barthwal MK, Dikshit M. Interaction of inducible nitric oxide synthase with Rac2 regulates reactive oxygen and nitrogen species generation in the human neutrophil phagosomes: implication in microbial killing. Antioxid Redox Signal. 20: 417-431, 2014.
  • Khanna V, Jain M, Singh V, Kanshana JS, Prakash P, Barthwal MK, Murthy PSR, Dikshit M.Cholesterol diet withdrawal leads to an initial plaque instability and subsequent regression of accelerated iliac artery atherosclerosis in rabbits. PLOS One,8: e77037,2013.
  • Singh V, Jain M, Misra A, Khanna V, Rana M, Prakash P, Malasoni R, Dwivedi AK, Dikshit M, Barthwal MK. Curcuma oil ameliorates hyperlipidaemia and associated deleterious effects in golden Syrian hamsters. Br J Nutr. 110: 437-446, 2013.
  • Misra A, Srivastava S, Ankireddy SR, Islam NS., Barthwal MK, Dikshit M. PhospholipaseCγ2 via p38 and ERK MAP kinase mediate DPV-Asn induced human platelet aggregation and CD40L release. Redox Report, 18: 174-85, 2013.
  • Jain M, Surin WR, Misra A, Prakash P, Singh V, Khanna V, Kumar S, Siddiqui HH, Raj K, Barthwal MK, Dikshit M. Antithrombotic activity of a newly synthesized coumarin derivative 3-(5-Hydroxy-2,2-dimethyl-chroman-6-yl)-N-{2-[3-(5-hydroxy-2,2-dimethyl-chroman-6-yl)-propionylamino]-ethyl}propionamide. Chem Biol Drug Des. 81: 499-508, 2013.
  • Keshari RS, Verma A, Barthwal MK, Dikshit M. Reactive oxygen species-induced activation of ERK and p38 MAPK mediates PMA- induced NETs release from human neutrophils.  J Cell Biochem. 114: 532-40, 2013.
  • Keshari RS, Jyoti A, Dubey M, Kothari N, Kohli M, Bogra J, Barthwal MK, Dikshit M. Cytokines induced neutrophil extracellular traps formation: implication for the inflammatory disease condition. PLOS One7: e48111, 2012.
  • Jain M, Barthwal MK, Haq W, Katti SB.Dikshit M.Novel arginine analogs as potential inhibitors of acetylcholine induced relaxation in rat thoracic aortic rings. Chem Biol Drug Design 79: 459-69, 2012.
  • Kothari N, Bogra J, Kohli M, Malik A, Kothari D, Srivastava S, Keshari RS, Singh V, Barthwal MK, Dikshit M. Role of active nitrogen molecules in the progression of septic shock.  Acta Anaesthesiol Scand. 56: 307-315, 2012.
  • Keshari RS, Jyoti A, Kumar S, Dubey M, Verma A, Srinag BS, Krishnamurthy H, Barthwal MK,Dikshit M. Neutrophil extracellular traps contain mitochondrial as well as nuclear DNA and exhibit inflammatory potential.Cytometry A.81: 238-247, 2012.
  • Saluja R, Chatterjee M, Jyoti A, Sinha S, Habib S, Verma A, Mitra K, Barthwal MK, Bajpai VK,Dikshit M. Molecular and biochemical characterization of nitric oxide synthase isoforms and their intracellular distribution in human peripheral blood mononuclear cells.BBA Mol Cell Res 1813: 1700-1707, 2011.
  • Prakash P,Khanna V, Singh V, Jain M, Keshari, RS, Barthwal MK, Dikshit M. Atorvastatin protects against ischemia-reperfusion injury in fructose induced insulin resistant rats. Cardiovascular Drugs Therapy 25: 285-297, 2011.
  • Khanna V, Jain M, Barthwal MK, Kalita D, Boruah JJ, Das SP, Islam NS, Ramasarma T and Dikshit M. Vasomodulatory effect of novel peroxo-vanadate compounds on rat aorta: Role of Rho kinase and nitric oxide/cGMP pathway. Pharmacol Res, 64: 274-282, 2011.
  • Kothari N, Keshari RS, Bogra J, Kohli M, Abbas H, Malik A, Dikshit M, Barthwal MK. Increased myeloperoxidase enzyme activity in plasma is an indicator of inflammation and onset of sepsis. J Crit Care, 26:435e 1-7, 2011.
  • Kumar S, Barthwal MK, Dikshit M.Nitrite mediated modulation of HL-60 cell cycle and proliferation: Involvement of Cdk2 activation. J Pharmacol Exp Therap 337: 812-821, 2011.
  • Singh V, Jain M, Prakash  P, Misra A, Khanna V, Tiwari RL, Keshari RS, Singh S, Dikshit  M, Barthwal MK. A time course study on pro-thrombotic parameters and their modulation by anti-platelet drugs in hyperlipidemic hamsters. J Physiol Biochem 67:205-216, 2011.
  • Prakash P, Misra A, Surin WR, Jain M, Bhatta R, Pal R, Raj K, Barthwal MK,Dikshit M.Anti-platelet effects of Curcuma oil in experimental models of myocardial ischemia-reperfusion and thrombosis. Thrombosis Res127: 111-118, 2011.
  • Sashidhara KV, Kumar A, Kumar M, Singh S, Jain M, Dikshit M. Synthesis of novel 3-carboxamide-benzocoumarin derivatives as orally active antithrombotic agents. Bioorg Med Chem Lett. 21: 7034-7040, 2011.
  • Akinmoladun AC, Obuotor EM, Barthwal MK, Dikshit M, Farombi EO. Ramipril-like activity of spondias mombin linnagainst no-flow ischemia and isoproterenol-induced cardiotoxicity in rat heart. Cardiovasc Toxicol. 10:295-305, 2010.
  • Kumar S, Patel S, Jyoti A, KeshariRS, Verma A, Barthwal MK, Dikshit M.Nitric oxide mediated augmentation of neutrophil reactive oxygen and nitrogen species formation: critical use of probes. Cytometry Part A, 77: 1038-1048, 2010.
  • Kumar N, Misra P, Dube A, Bhattacharya S, Dikshit M, Ranade S.Piper betle Linn. a maligned Pan-Asiatic plant with an array of pharmacological activities and prospects for drug discovery.Current Science 99: 922-932, 2010.
  • Singh S, Kumar S, Dikshit M. Involvement of the mitochondrial apoptotic pathway and nitric oxide synthase in dopaminergic neuronal death induced by 6-hydroxydopamine and lipopolysacchride. Redox Report 15: 115-122, 2010.
  • Kumar S, Jyoti A, Keshari R, Barthwal MK, Dikshit M. Functional and molecular characterization of NOS isoforms in rat neutrophil precursor cells. Cytometry Part A 77:467-477, 2010.
  • Kumar S, Barthwal MK and Dikshit M. CDK2-Nitrosylation and loss of mitochondrial potential mediates NO dependent biphasic effect on HL-60 cell cycle. Free Rad Biol Med 48:  851-861, 2010.
  • Saluja R, Saini R, Mitra K, Bajpai VK, Dikshit M. Ultrastructural immunogold localization of nitric oxide synthase isoforms in rat and human eosinophils. Cell & Tissue Res 340: 381-388, 2010. ErratumCell & Tissue Res 340: 381-388, 2010.
  • Patel S, Kumar S, Jyoti A, Srinag BS,KeshariRS, Saluja R, Verma A, Mitra K, Barthwal MK, Krishnamurthy H, Bajpai VK, and Dparikshit M. Nitric oxide donors release extracellular traps from human neutrophils by augmenting free radical generation. Nitric Oxide Biol. Chem 22: 226-234,2010.
  • Mishra JK, Samanta K, Jain M, Dikshit M, Panda G. Amino acid based enantiomerically pure 3-substituted benzo fused heterocycles: A new class of anti-thrombotic agents. Bioorg Med Chem Lett.20:244-247, 2010. 
  • Babu CK, Ansari KM, Mehrotra S, Patel S, Dikshit M, Das M. Activation of inflammatory response and apoptosis of polymorphonuclear leukocytes in patients with argemone oil poisoning. Chem Biol Interact., 183:154-64, 2010.
  • Surin WR, Prakash P, Barthwal MK andDikshit M. Optimization of ferric chloride induced thrombosis model in rats: Effect of anti-platelet and anti-coagulant drugs J Pharamacol Toxicol Methods, 61: 287-291, 2010.
  • Chatterjee M, Saluja R, Tewari S, Barthwal MK, Goel SK,Dikshit M. Augmented nitric oxide generation in neutrophils: oxidative and pro-inflammatory implications in hypertension. Free Rad Res 43: 1195-1204, 2009.
  • Husain M, Shukla R, Dikshit M, Maheshwari PK, Nag D, Srimal RC, Seth PK, Khanna VK. Altered platelet monoamine oxidase-B activity in idiopathic Parkinson's disease. Neurochem Res. 34: 1427-32, 2009.
  • Srikanth GVN, Prakash P, Tripathy NK, Dikshit M, and Nityanand S. Establishment of a rat model of myocardial infarction with a high survival rate: a suitable model for myocardial regenerative therapy. J Stem Cells Regenerative Med, 5:30-36, 2009.
  • Patel S, Vemula J, Konikkat S, Barthwal MK, Dikshit M. Ion channel modulators mediated alterations in NO induced free radical generation and neutrophil membrane potential. Free Rad Res, 43: 514-521, 2009.
  • Chatterjee M, Saluja R,Kumar V, Jain GK, Barthwal MK,Dikshit M.Ascorbate sustains neutrophil NOS expression, catalysis and oxidative burst. Free Rad Biol Med. 45: 1084-1093, 2008.
  • Kumar S, Saran RK, Puri A, Gupta N, Sethi R, Surin WR, Dikshit M, Dwivedi SK, Narain VS, Puri VK. Profile and prevalence of clopidogrel resistance in patients of acute coronary syndrome. Indian Heart J. 59: 152-156, 2007.
  • Santhanam AVR, Viswanathan S, Dikshit M. Activation of protein kinase b/Akt and endothelial nitric oxide synthase mediates agmatine-induced endothelium-dependent relaxation. Eur J Pharmacol. 572: 189-196, 2007.
  • Sharma P, Singh S, Siddiqui TI. Singh VS, Kundu B, Prathipati P, Saxena AK, Dikshit DK, Rastogi L, Dixit C, Gupta MB, Patnaik GK, Dikshit M. α-Amino acid derivatives as proton pump Inhibitors and potent anti-ulcer agents. Eur J Med Chem. 42: 386-393, 2007.
  • Gupta R, Chakrabarti P, Dikshit M,Dash D. Late signaling in the activated platelets upregulates tyrosine phosphatase SHP1 and impairs platelet adhesive functions: Regulation by calcium and Src kinase. BBA Mol Cell Res.1773: 131-140, 2007.
  • Chatterjee M, Saluja R, Kanneganti S, Chinta S, Dikshit M. Biochemical and molecular evaluation of neutrophil NOS in spontaneously hypertensive rats. Cell Mol Biol. 53: 84-93, 2007.
  • Sankaranarayanan A, Narender T, Kumar S,Dikshit M. Allium sativum constituents: Effect on free radical generation from ratneutrophils. Cell Mol Biol. 53: 63-67, 2007.
  • Saini R, Patel S, Saluja R, Sahasrabuddhe AA, Singh MP, Habib S, BajpaiVK, Dikshit M. Nitric oxide synthase localization in the rat neutrophils: immunocytochemical, molecular and biochemical studies. J Leukocyte Biol. 79: 519-528, 2006.
  • Shukla R, Rajani M, Srivastava N, Barthwal MK, Dikshit M.Nitrite and malondialdehyde content in the cerebrospinal fluid of patients with Parkinson’s disease. Int J Neurosciences 116: 1391-1402, 2006.
  • Das A, Dikshit M, Nath C. Role of molecular isoforms of acetylcholinesterase in learning and memory functions. Pharmacol. Biochem. Behav. 81:89-99, 2005.
  • Singh S, Das T, Ravindran A, Chaturvedi RK, Shukla Y, Agarwal AK,Dikshit M. Involvement of nitric oxide in neurodegeneration: A study on the experimental models of Parkinson’s disease. Redox Report 10: 103-109, 2005.
  • Das A,Rai D, Dikshit M, Palit G, Nath C. Nature of stress: differential effects on brain acetylcholinesterase activity and memory in rats.Life Sciences 77:2299-2311, 2005.
  • Saxena HM, Dikshit M. Abrogation of DTH response and mitogenic lectin - and alloantigen - induced activation of lymphocytes by calcium inhibitors, TMB-8 and BAPTA-AM.Immunol Lett. 101: 60-64, 2005.
  • Sadiq PA, Puri A, Dikshit M, Ghatak A, Dwivedi SK, Narain VS, Saran RK, Puri VK.Profile and prevalence of aspirin resistance in Indian patients with coronary artery disease. Ind Heart J. 57: 658-661, 2005.
  • Wadhawan V, Karim Z A., Mukhopadhyay S, Gupta R, Dikshit M, Dash D. Platelet storage under in vitro condition is associated with calcium-dependent apoptosis-like lesions and novel reorganization in platelet cytoskeleton. Arch Biochem Biophys. 422: 183-190, 2004.
  • Shukla R, Barthwal MK, Srivastava N, Sharma P, Raghavan S.AV, Nag D, Srimal RC, Seth PK, Dikshit M. Neutrophil free radical generation and enzymatic antioxidants in the migraine patients. Cephalgia 24: 37-43, 2004.
  • Sharma P, Raghavan SAV, Dikshit M. Ascorbate-mediated enhancement of reactive oxygen species generation from polymorphonuclear leukocytes: modulatory effect of nitric oxide.  J Leuko Biol. 75: 1070-1078, 2004.
  • Pandey VK, Tusi S, Tusi Z, Raghubir R, Dikshit M, Joshi MN, Bajpai SK. Thiadiazolyl quinazolones as potential antiviral and antihypertensive agents. Ind J Chem Section B-Org Chem Including Med Chem. 43: 180-183, 2004.  
  • Batra S, Roy A K, Patra A, Bhaduri AP,Surin WR, Raghavan SAV, Sharma P, Kapoor K and Dikshit M. Baylis-Hillman reaction assisted parallel synthesis of 3, 5-disubstituted isoxazoles and their in vivo bioevaluation as antithrombotic agents. Bioorg Med Chem. 12: 2059-2077, 2004.
  • Das A, Dikshit M, Singh HK, Nath C. Evaluation of effect of scopolamine on stages of active avoidance learning in rats. Ind J Pharmacol. 35: 47-50, 2003.
  • Shukla R, Khanna VK, Husain MF, Tandon R, Nag D, Dikshit M, Srimal RC, Seth PK. Platelet [3H]-Ketanserin binding in tension type headache. Headache, 43: 103-108, 2003.
  • Batra S. Srinivasan T. Rastogi SK, Patra A, Bhaduri AP, Dikshit M. Isoxazole-based derivatives from Baylis-Hillman chemistry: assessment of preliminary hypolipidemic activity. Bioorg Med Chem. 11: 2269-2276, 2003.
  • Shukla R, Rajani M. Barthwal MK, Srivastava N, Dikshit M. Cerebrospinal fluid nitrite and malondialdehyde levels in patients with motor neuron disease. Intern J Neuroscience, 113:1043-1054, 2003.
  • Raghavan SAV, Sharma P, Dikshit M. Role of ascorbic acid in the modulation of inhibition of platelet aggregation by polymorphonuclear leukocytes. Thrombosis Res. 110: 117-126, 2003.
  • Sharma P, Raghavan SAV, Dikshit M. Role of ascorbate in the regulation of nitric oxide generation by polymorphonuclear leukocytes. Biochem Biophys Res Commun. 309: 12-17, 2003.
  • Tewari R, Singh MP, Farheen S, Dikshit M, Mehrotra PK. Inhibition of platelet aggregation by rat trophoblasts. Med Principles Pract. 11: 100-104, 2002.
  • Srivastava P, Rajnikanth M, Raghavan SAV, Dikshit M. Role of endogenous reactive oxygen derived species and cyclooxygenase mediators in 5-hydroxytryptamine induced contractions in rat aorta: relationship to nitric oxide. Pharmacol Res. 45:375-382, 2002.
  • Srivastava N, Barthwal MK, Dalal PK, Agarwal AK, Nag D, Seth PK, Srimal RC, Dikshit M. A study on nitric oxide, beta adrenergic receptors and antioxidant status in the polymorphonuclear leukocytes from the patients of depression. J Affective Disorder, 47: 45-52, 2002.
  • Sharma P, Barthwal MK, Dikshit M. NO Synthesis and its regulation in the arachidonic acid stimulated rat polymorphonuclear leukocytes.Nitric Oxide Biol. Chem. 7: 119-126, 2002.
  • Batra S. Srinivasan T. Rastogi SK, Kundu B, Patra A, Bhaduri AP, Dikshit M: Combinatorial synthesis and biological evaluation of isoxazole-based libraries as antithrombotic agents. Bioorg. Med. Chem. Let. 12: 1905-1908, 2002.
  • Das A, Dikshit M, Srivastava SR, Srivastava UK, Nath C. Effect of ovariectomy and estrogen supplementation on brain acetylcholine esterase activity and passive avoidance learning in rats. Can J Physiol Pharmacol. 80: 907-914, 2002.
  • Singh MP, Sinha S, Raghavan SAV, Dikshit M. Inhibition of platelet aggregation by rat globin. Thrombosis Research, 107: 201-207, 2002.
  • Das A, Rai D, Dikshit M, Palit G, Nath C. Effect of unpredictable stress on cognition and brain acetyl cholinesterase activity. Ind J Pharmacol. 34: 416-422, 2002.
  • Dikshit M,Sharma P. Nitric oxide mediated modulation of free radical generation response in the rat polymorphonuclear leukocytes: A flow cytometric study. Methods Cell Sci. 24: 69-76, 2002.
  • Raghavan SAV, Srivastava P, Dikshit M.Altered contractions to endothelin-1, phenylephrine, potassium chloride and relaxations to acetylcholine at various stages of renal hypertension in the rat. Pharmacol Res. 43: 225-232, 2001.
  • Das A, Dikshit M, Nath C. Profile of acetylcholine esterase in brain areas of male and female rats of adult and old aged Life Sciences, 68: 1545-1555, 2001.
  • Shukla R, Barthwal MK, Srivastava N, Nag D, Seth PK, Srimal RC, Dikshit M. Blood nitrite level in Migraine patients during headache-free period. Headache, 41: 475-481, 2001.
  • Shukla R, Khanna VK, Husain M, Tandon R, Pradeep S, Nag D, Dikshit M, Srimal RC, Seth PK: Platelet [3H]-Ketanserin binding in migraine. Cephalgia, 21: 567-572, 2001.
  • Dixit C, Dikshit M. A flowcytometric method for evaluation of acid secretion from isolated rat gastric mucosal cells. J Pharmacol Toxicol Methods, 45: 47-53, 2001.
  • Saxena AK, Pandey SK, Seth P, Singh MP, Dikshit M, Carpy A. Synthesis and QSAR studies in 2-(N-aryl-N-aroyl) amino-4,5-dihyrothiazole derivatives as potential antithrombotic agents. Bioorg Med Chem. 9: 2025-2034, 2001.
  • Sethi S, Sharma P, Dikshit M. Nitric oxide and oxygen derived free radical generation from control and lipopolysaccharide treated rat polymorphonuclear leukocyte. Nitric Oxide Biol. Chem. 5: 482-493, 2001.
  • Srivastava N, Barthwal MK, Dalal PK, Agarwal AK, Nag D, Seth PK, Srimal RC, Dikshit M. Nitrite content and antioxidant enzyme levels in the blood of schizophrenia patients. Psychopharmacology, 158: 140-145, 2001.
  • Raghavan SAV, Dikshit M. Augmented relaxation to L-citrulline in lipopolysaccharide treated rat aorta: possible role of L-citrulline in endotoxaemia.Eur J Pharmacol. 431: 61-69, 2001.
  • Barthwal MK, Srivastava N, Dikshit M. Role of nitric oxide in a progressive neurodegeneration model of Parkinson’s disease. Redox Report, 6: 297-302, 2001.
  • Barthwal MK, Srivastava N, Shukla R, Nag D, Seth PK, Srimal RC, Dikshit M. Antioxidant levels in the rat brain after nitric oxide synthase inhibition: A preliminary report. Redox Report, 5: 75-80, 2000.
  • Sethi S, Singh MP, Dikshit M. Mechanisms involved in the augmented free radical generation from rat neutrophils. Thrombosis Res. 98: 445-450, 2000.
  • Das A, Kapoor K, Sayeepriyadarshini AT, Dikshit M, Palit G, Nath C. Immobilisation stress induced changes in brain acetylcholine esterase activity and cognitive function in mice. Pharmacol Res. 42: 213-217, 2000.
  • Sethi S, Singh MP, Dikshit M. Nitric oxide mediated augmentation of polymorphonuclear free radical generation following hypoxia-reoxygenation. Blood, 93: 333-340, 1999.
  • Dixit C, Rastogi L, Dikshit M. Effect of nitric oxide modulators on experimentally induced peptic ulcer in the rat. Pharmacol Res. 39: 33-40, 1999.
  • Barthwal MK, Srivastava N, Shukla R, Nag D, Seth PK, Srimal RC, Dikshit M. Polymorphonuclear leukocyte nitrite content and antioxidant enzymes in Parkinson’s disease patients. Acta Neurol Scand. 100: 300-304, 1999.
  • Tripathi RC, Pandey SK, Kar K, Dikshit M, Saxena AK. Synthesis and SAR studies of 1-substituted-n-(4-alkoxycarbonylpiperidin-1-yl) alkanes as potent anti-arrhythmic agents. Bioorg Med Chem Lett. 9: 2693-2698, 1999.
  • Kumari R, Singh MP, Seth P, Dikshit M. Inhibition of platelet aggregation by a factor present in the rat peripheral neutrophil supernatant. Thrombosis Res. 91: 75-82, 1998.
  • Rastogi L, Patnaik GK, Dikshit M. Free radicals and antioxidants status in the rat stomach after pyloric ligation induced ulcers. Pharmacol Res. 38: 125-132, 1998.
  • Nath C, Rastogi L, Dikshit M, Patnaik GK, Saxena RC and Gupta MB. Interferon inducer Poly I: Poly C - A potent antigastric ulcer agent and inhibitor of gastric proton pump in rats. Clin Expt Pharmacol Physiol. 25: 564-567, 1998.
  • Hegde, LG, Srivastava P, Kumari R, Dikshit M. Alterations in the vasoreactivity of hypertensive rat aortic rings: Role of nitric oxide and superoxide radicals. Clin Exp Hypertension, 20: 817-832, 1998.
  • Srivastava P, Hegde LG, Patnaik GK, Dikshit M. Role of endothelial derived reactive oxygen species and nitric oxide in norepinephrine-induced rat aortic ring contractions. Pharmacol Res. 38: 265-274, 1998.
  • Hegde LG, Shukla R, Srimal RC, Dikshit M: Attenuation in the brain nitric oxide synthase activity in coarctation model of hypertension in rats. Pharmacol Res. 36: 109-114, 1997.
  • Seth P, Kumari R, Dikshit M. Alteration in the free radical generation and nitric oxide release from rat polymorphonuclear leukocytes following thrombosis. Thrombosis Res. 87: 279-288, 1997.
  • Tandon R, Singh, MP, Haq W, Dikshit M, Patnaik GK, Dhar MM: Synthesis of novel tetra peptides as potential ACE inhibitors. Ind J Chem. 36B: 386-390, 1997.
  • Shukla A, Dikshit M, Srimal RC. Nitric oxide-dependent blood-brain barrier permeability alteration in the rat brain. Experientia, 52: 136-40, 1996.
  • Dikshit M, Chari S, Seth P, Kumari R. Effect of nitric oxide synthase inhibitors and their antipodes on rat polymorphonuclear leukocyte luminol dependent chemiluminescence response. Brit J Pharmacol. 119: 578-582, 1996.
  • Shukla A, Dikshit M, Srimal RC. Nitric oxide modulates blood-brain barrier permeability during infections with an inactivated bacterium. Neuroreport, 6: 1629-1632, 1995.
  • Kumari R, Seth P, Dikshit M. Involvement of bio-antioxidants in thrombosis in mice. Redox Report, 7: 191-195, 1995.
  • Shukla A, Dikshit M, Srimal RC. Status of bio-antioxidants in brain micro vessels of monkey and rat. Free Rad Res. 22: 303-308, 1995.
  • Dikshit M, Rastogi L, Shukla R, Srimal RC. Prevention of ischemia induced biochemical changes by curcumin and quinidine in the cat heart. Ind J Med Res. 101: 31-35, 1995.
  • Seth P, Kumari R, Dikshit M, Srimal RC. Effect of PAF-Antagonists in the models of thrombosis. Thrombosis Res. 76: 503-512, 1994.
  • Hegde LG, Shukla R, Dikshit M, Srimal RC. A study on the central cardiovascular regulation in the cat by L-Arginine-EDRF/NO-cGMP pathway. Arch Int Pharmacodyn Ther. 328: 155-164, 1994.
  • Seth P, Kumari R, Dikshit M, Srimal RC. Modulation of rat polymorphonuclear leukocyte response by nitric oxide and arginine. Blood, 84: 2741-2748, 1994.
  • Kumari R, Seth P, Dikshit M, Srimal RC. Alterations in the bio-antioxidants following thrombosis. Free Radical Biol Med. 17: 481-484, 1994.
  • Dikshit M,Chalecka-Franaszek E, Nalepa I. Centpropazine affinity to cortical noradrenergic receptors and effect on their responsiveness. J Pharma Pharmacol. 45: 228-230,1993.
  • Shukla A, Shukla R, Dikshit M, Srimal RC. Alterations in free radical scavenging mechanisms following blood-brain barrier disruption. Free Radical Biol Med. 15: 97-100, 1993.
  • Dikshit M, Kumari R, Srimal RC: Pulmonary thromboembolism induced alterations in the nitric oxide release from the rat neutrophils. J Pharmacol Exp Therap. 265: 1369-1373, 1993.
  • Kumari R, Dikshit M, Srimal RC: Free radical scavenging mechanisms during pulmonary thromboembolism in rats. Thrombosis Res. 69: 101-111, 1993.
  • Dikshit M,Seth P, Srimal RC. Effect of molsidomine and free radical scavengers on the pulmonary thromboembolism in mice. Thrombosis Res. 70: 317-327, 1993.
  • Dikshit M,Oosten MHMV, de Graff S, Srimal RC. Free radical production and scavenger mechanisms in the rabbit heart and the protective effect of verapamil. Arch Int Pharmacodyn Ther. 318: 55-65, 1992.
  • Dikshit M, Kumari R, Srimal RC. Effect of pulmonary thromboembolism on circulating neutrophils in mice. Thrombosis Res. 66: 133-139, 1992.
  • Dikshit M,Srimal RC. Effect of centbucridine on biochemical changes in isoproterenol induced ischemia in rats. Ind J Med Res. 94: 307-311, 1991.
  • Dikshit M,Srimal RC. Evidence for the presence of a new plasma factor, which acts synergistically to ADP, induced platelet aggregation. Life Sciences, 47: 117-126, 1990.
  • Dikshit M,Kar K, Srimal RC. Effect of alpha adrenergic receptor blockers on vulnerability to ventricular fibrillations in the cat. Arch Int Pharmacodyn Ther. 302: 119-127, 1989.
  • Dikshit M, Srivastava R, Srimal RC, Dhawan BN: Modification of ischemia induced biochemical changes in the myocardium by Rooh-afza extracts. Drug Dev Res. 17: 245-252, 1989.
  • Dikshit M, Srivastava R, Srimal RC. Role of free radicals in pulmonary thromboembolism in mice. Thrombosis Res. 55: 549-557, 1989.
  • Dikshit M, Srivastava R, Kundu B, Mathur KB, Kar K. Antiarrhythmic and antithrombotic effect of anti-arrhythmic peptide and its synthetic analogues. Ind J Exp Biol. 26: 874-876, 1988.
  • Dikshit M,Ansari MS, Pandey VC, Kar K. Effect of quinidine on myocardial enzyme activities following myocardial infarction in the cat. Ind J Med Res. 85: 85-90, 1987.
  • Dikshit M, Srivastava R, Kar K, Srimal RC. Anti-thrombotic effect of some platelet modifying drugs. Thrombosis Res. 46: 397-403, 1987.
  • Bhatnagar M,Pande M, Dubey MP, Dhawan BN. Effect of centhaquin on spontaneous and evoked release of norepinephrine from isolated perfused rabbit heart. Arzen For/Drug Res. 35: 693-697, 1985.
  • Pande M, Kar K, Dhawan BN. Effect of anti-arrhythmic drugs on ventricular threshold and cardiac stores of norepinephrine in the cat. Ind J Pharmacol. 17: 103-107, 1985.
  • Srivastava R, Dikshit M, Srimal RC, Dhawan BN: Antithrombotic effect of curcumin. Thrombosis Res. 40: 413-418, 1985.
  • Pande M, Bhatnagar M, Pandey VC, Kar K, Dhawan BN. Effect of cardiac arrhythmias and anti-arrhythmic drugs on myocardial acetylcholine esterase in the cat. Ind J Med Res. 80: 360-364, 1984.
  • Pande M, Bhatnagar M, Pandey VC, Kar K, Dhawan BN. Effect of experimental arrhythmias and anti-arrhythmic drugs on lactate dehydrogenase and succinate dehydrogenase activity in the cat heart. Ind J Exp Biol. 22: 149-153, 1984.
  • Bhatnagar M, Pande M, Dubey MP, Dhawan BN. Effect of guanethidine on spontaneous and evoked release of norepinephrine from isolated perfused rabbit heart.Ind J Exp Biol. 21: 265-271, 1983.
  • Pande M, Bhatnagar M, Pandey VC, Kar K, Dhawan BN. Effect of anti-arrhythmic drugs on the serum free fatty acids levels during experimental cardiac arrhythmias in the cat. Pharmacol Res. 15: 951-957, 1983.
  • Pande M, Kar K, Bhatnagar M, Dubey MP, Dhawan BN. Supraspinal influences on ventricular fibrillation threshold and cardiac stores of norepinephrine in the cat. Arch Int Pharmacodyn Ther. 255: 117-130, 1982.
  • Bhatnagar M, Dubey MP, Pande M, Dhawan BN. Effect of clonidine on spontaneous and evoked norepinephrine release from isolated perfused rabbit heart.Ind J Exp Biol. 19: 1040-1046, 1981.

Review Articles

  • Gaikwad AN, Kumar S, Dikshit M. Recent advancement in nitric oxide research in India. Proc Ind Natl Sci Acad. 84, (in press), 2018.
  • Kulkarni SR, Dikshit M. Indian marine pharmacology: A sneak peek into the ecosystem.  Proc Ind Natl Sci Acad. (in press), 2018.
  • Dikshit M, Dikshit DK. Drug discovery research in India, Current Science, 111: 252-255, 2016.
  • Misra A, Dikshit M. Platelets and arterial thrombosis: evolving role of platelet GPVI as an antithrombotic drug target. Proc Ind Nat Sci Acad. 80: 289-299, 2014.
  • Sánchez-Gómez FJ, Espinosa-Díez C, Dubey M, Dikshit M, Lamas S. S-Glutathionylation: relevance in diabetes and potential role as a biomarker. Biol Chem. 394: 1263-1280, 2013.
  • Singh V, Tiwari RL, Dikshit M, Barthwal MK. Models to study atherosclerosis: a mechanistic insight. Curr Vasc Pharmacol.7: 75-109, 2009.
  • Chatterjee M, Dikshit M. The Ascorbate resistance to pathogenic invasions: possible implications during infections and for better health. Proc Natl Acad Sci. (Section B, Ind) 79: 34-44, 2009.
  • Panday SK, Dikshit M, Dikshit DK. Synthesis of N-[3’-(acetylthio)alkanoyl] and N-[3’-mercaptoalkanoyl]-4-S)-(phenylmethyl)pyroglutamic acids and prolines as potent ACE inhibitors, Med. Chem Res. 18: 566-578, 2009.  
  • Surin WR, Barthwal MK, Dikshit M. Platelet collagen receptors, signalling and antagonism: Emerging approaches for the prevention of intra-vascular thrombosis. Thrombosis Res. 122: 786-803, 2008.
  • Singh S, Dikshit M. Apoptotic neuronal death in Parkinson’s disease: Involvement of nitric oxide. Brain Res. 54: 233-250, 2007.
  • Kavya R, Rohit Saluja R, Singh S, Dikshit M. Nitric oxide synthase regulation and diversity: Implications in Parkinson's disease. Nitric Oxide Biol. Chem. 15: 280–294, 2006.  
  • Singh MP, Patel S, Dikshit M, Gupta YK. Contribution of genomics and proteomics in understanding the role of modifying factors in Parkinson's disease.
  • Ind J Biochem Biophys. 43: 9-81, 2006.
  • Kapoor K,Dikshit M.Transgenic and Gene knockout rodents as research tools for cardiovascular diseases. Scand J Lab Anim Sci. 32, 1-19,2005. (Impact Factor 0.211)
  • Kavya R, Dikshit M. Role of nitric oxide/nitric oxide synthase in Parkinson’s disease. Annals Neurosciences, 12, 1-5, 2005.
  • Raghavan SAV, Dikshit M. Vascular regulation by the L-arginine metabolites, nitric oxide and agmatine. Pharmacol Res. 49: 397-414, 2004.
  • Jayakar SS, Dikshit M. AMPA receptor regulation mechanisms: Future target for safer neuroprotective drugs.Intern J Neuroscience, 114: 695-734, 2004.
  • Raghavan SAV, Dikshit M. Recent Advances in the Status and Targets of Antithrombotic Agents. Drugs of Future 27: 669-683, 2002.
  • M Dikshit, Barthwal MK. Role of nitric oxide and free radicals in Parkinson’s disease: An overview. Annals of Neurosciences, 8: 89-97, 2001.
  • Dikshit M. Status report on pharmacology of autacoids. Reviews of Research in Pharmacology in India (1994-1998), Published by Indian National Science Academy, New Delhi, India, Ind J Pharmacol. 32: S3-S14.  2000.
  • Sethi S, Dikshit M. Modulation of polymorphonuclear leukocyte function by nitric oxide. Thrombosis Res. 100: 223-247, 2000.
  • Dikshit M,Kumari R. Modulation of platelet aggregation response by factors released from polymorphonuclear leukocytes. Hematology, 2: 39-53, 1997. 

Book Chapters

  • Prakash P, Surin WR, Barthwal MK, Dikshit M. Advancements in the new anti-thrombotic drug development. "Recent Advances in Herbal Drug Research and Therapy” (Eds: A Ray and K Gulati) IK International, New Delhi, pp 130-163, 2010.
  • Kumar S,Dikshit M. Neutrophil phagocytosis assay. Flow cytometry lab protocols: Protocols from the international cytometry workshops, (Ed: Krishan A) pp 49-51; 2010
  • Kumar S, Dikshit M. Respiratory burst / free radical assay. Flow cytometry lab protocols: Protocols from the international cytometry workshops, (Ed: Krishan A) pp 53-56; 2010.
  • Saini R, Chatterjee M, Dikshit M. Neutrophil nitric oxide synthase: functional, biochemical and molecular perspective. "Current Trends in Pharmacology" (Eds: A Ray and K Gulati) IK International, New Delhi, pp 327-365, 2007.
  • Surin W.R. Dikshit M. Prevention of intravascular thrombosis: Research on Indian herbs and spices. In: Herbal Drug Research: A Twenty-first Century Perspective, (Eds: RK Sharma and R Arora) M/s Jaypee Brothers Medical Publishing Limited, New Delhi, pp 432-444, 2006.
  • Saini R, Bajpai VK, Dikshit M. Characterization and localization of nitric oxide synthase in rat polymorphonuclear leukocytes. Natural antioxidants and micronutrients. 3rd International Symposium on Micronutrients and Natural Antioxidants - ISMNSA and 2nd Meeting of the Society for Free Radical Research - SFRR Asia (China, Shanghai, June 24-29, 2005). (Eds. Zhao, B., Liu, G, Packer L) Medimond Bologna, Italy, pp 67-71, 2005.
  • Sharma P, Dikshit M. Mechanisms involved in the regulation of free radical generation from neutrophils. In: Pharmacological Perspectives of some Toxic Chemicals and Antidotes (Eds. Flora SJS, Romano JA, Baskin SI, Sekhar K.) Narosa Publishing House, pp 303-330, 2004.
  • Sharma P, Dikshit M. Nitric oxide mediated modulation of free radical generation response in the rat polymorphonuclear leukocytes: Applications in Biological Research. (Eds, Sobti RC and Krishnan A) Kluwer Academic Press, pp 69-76, 2003.
  • Srimal RC, Dikshit M. Current trends in anti-thrombotic drug research. In: Proceedings of International Conference on Atherosclerosis (Ed S. Singh), pp 83-90, 1998.

Patents

Patent Number(S): IN192822-B
Assignee: COUNCIL SCI&IND RES INDIA
Inventor(S): Dikshit D K, Dikshit M,Sharma P, Srivastava S

Patent Number(S): US2007287723-A1
Assignee: COUNCIL SCI & IND RES INDIA
Inventor(S): Gaur S, Fatima Z, Dixit A, Ali Z, Surin W R, Kapoor K, Bhutani K, Ansari M S, Dikshit M, Saxena A K

Patent Number(S): IN200101196-I1Assignee: COUNCIL SCI & RES
Inventor(S): Dikshit D K; Dikshit M; Srivastava S, Sharma P.

Patent Number(S): US2006142322-A1; US7601838-B2Assignee: Gaur S; Fatima Z; Dixit A; Et Al.
Inventor(S): Gaur S, Fatima Z, Dixit A, Ali Z, Surin W R, Kappor K, Bhutani K, Ansari M S, Dikshit M,Saxena A K

Patent Number(S): WO2006070385-A1; IN200501258-P1
Assignee: COUNCIL SCI & IND RES INDIA; GAUR S; FATIMA Z; Et Al.
Inventor(S): Gaur S, Fatima Z, Dixit A, Ali Z, Surin W R, Kappor K, Bhutani K, Ansari M S,