People : Scientific : Faculty & Scientists

DR. VIKAS SOOD, Ph.D 

Senior Scientist
+91-129-2876317 
vikas [at] thsti [dot] res [dot] in
Postdoctoral Training as Vaccine Research Innovation Awardee from Vaccine and Infectious Disease Research Center, THSTI
PhD from University of Delhi
Master of Science from Guru Nanak Dev University, Amritsar

·         Lata S., Ali A., Sood V., Raja R and Banerjea AC. HIV-1 Rev downregulates Tat expression and viral replication via modulation of  NAD(P)H:Quinine oxidoreductase 1 (NQO1). Nature Communications. 2015 June 10;6;7244.

 

·         Sharma M., Bhattacharya S., Nain M., Kaur M., Sood V., Gupta V., et. al. Japanese Encephalitis Virus Replication is Negatively Regulated by Autophagy and Occurs on LC3-I and EDEM1 containing Membranes. Autophagy 2014 Jul 16;10(9) 1637-51.

 

·         Lata S., Ronsard L., Sood V., Dar SA., Ramachandran VG., Das S et. al. Effect on HIV-1 gene expression, Tat-Vpr interaction and Cell apoptosis by natural variants of HIV-1 Tat exon 1 and Vpr from Northern India. PLoS One 2013 Dec 19;8(12):e82128

 

·         Kakumani PK., Ponia S., Rajgokul KS., Sood V., Chinnapan M., Banerjea AC. et. al. Role of RNAi in Dengue Viral Replication and Identification of NS4B as a RNAi Suppressor. J Virol.2013 Aug;87(16):8870-83. 

 

·         Kumar B, Khanna M, Kumar P, Sood V, Vyas R, Banerjea AC. Nucleic acid-mediated cleavage of M1 gene of Influenza A virus is significantly augmented by antisense molecules targeted to hybridize close to the cleavage site.   Mol Biotechnol. 2012 May;51(1):27-36.

 

  • Neogi U., Sharma Y., Sood V., Wanchu A. and Banerjea AC. Diversity of HIV-1 Long Terminal Repeat (LTR) Sequences following Mother-to-Child Transmission in North India. AIDS Research and Human Retroviruses. 2010 Dec:26(12):1299-305.

 

  • Karjee S., Manhas A., Sood V., Ponia SS., Banerjea AC, Chow V. et. al. The 7a accessory protein of SARS-CoV acts as an RNA silencing suppressor. J Virol. 2010 Oct;84(19):10395-401.

 

·        Neogi U*., Sood V*., Chowdhry A., Das S., Ramachandran VG., Sreedhar VK. et. al. Genetic Analysis of HIV-1 Circulating Recombinant Form 02_AG, B and C subtype specific Envelop Sequence from Northern India and their predicted co-receptor usage. AIDS Res Ther. 2009 Dec 3;6(1):28. *equal contribution

 

  • Bano AS*, Sood V*, Neogi U*, Goel N, Sreedhar K, Wanchu A. et. al. Genetic and Functional Characterization of HIV-1 VprC Variants from North India: Presence of Unique Recombinants with mosaic genomes from B, C and D subtypes within the ORF of Vpr. J Gen Virol. 2009 Nov;90(Pt 11):2768-76.*equal contribution

 

  • Sood V*, Ranjan R* and Akhil C Banerjea. Functional analysis of HIV-1 subtypes B and C HIV-1 Tat exons and RGD/QGD motifs with respect to Tat-mediated transactivation and apoptosis. AIDS. 2008 Aug 20;22(13):1683-5. *equal contribution

 

  • Rathore A., Chatterjee A., Sood V., Khan SZ., Banerjea AC., Yamamoto N and Dhole TN. Risk for HIV-1 infection is not associated with repeat-region polymorphism in the DC-SIGN neck domain and novel genetic DC-SIGN variants among North Indians. Clin Chim Acta. 2008 May;391(1-2):1-5. Epub 2008 Jan 12.

 

  • Neogi, U.*, Sood, V.*, Goel, N., Wanchu, A., Banerjea, A.C. Novel HIV-1 Long Terminal Repeat (LTR) sequences of Subtype B and mosaic intersubtype B/C Recombinants in North India. Arch Virol. 2008;153(10):1961-6.. *equal contribution

 

  • Sood V, Gupta N, Bano AS and Banerjea AC: DNA-enzyme mediated cleavage of HIV-1 GAG RNA is significantly augmented by antisense-DNA molecules targeted to hybridize close to the cleavage site. Oligonucleotides. 2007 17(1):113-21

 

  • Sood V, Gupta N, Shanker V, Bano AS and Banerjea AC: Basal RANTES promoter activity differs considerably among different species of monkeys: Implications for HIV-1/AIDS progression. AIDS. 2007 Jan 2; 21(1):116-8.

 

  • Sood V*, Unwalla H*, Gupta N, Chakraborti S and Banerjea AC: Potent knockdown of HIV-1 replication by targeting HIV-1 TAT/Rev sequences synergistically with catalytic RNA and DNA. AIDS. 2007 Jan 2; 21(1):31-40. *equal contribution 

 

  • Gupta N, Sood V, Bano A S and Akhil C Banerjea. X Protein of hepatitis B virus potently activates HIV-1 subtype C long terminal repeat promoter: implications for faster spread of HIV-1 subtype C. AIDS. 2007 Jul 11; 21(11):1491-2.

 

  • Bano A S, Gupta N, Sharma Y, Sood V, and Akhil C Banerjea. HIV-1 VprB and C RNA cleavage by potent 10-23 DNAzymes that also cause reversal of G2 cell cycle arrest mediated by Vpr genes. Oligonucleotides. 2007 Winter; 17(4):465-72.

 

  • Bano A S, Gupta N, Sood V and Akhil C Banerjea. Vpr from HIV-1 subtypes B and C exhibit significant differences in their ability to transactivate LTR-mediated gene expression and also in their ability to promote apoptotic DNA ladder formation. AIDS. 2007 Aug 20; 21(13):1832-4.

 

  • Gupta N, Bano A S, Sharma Y, Sood V and Banerjea A C. Potent Intracellular Knock Down of Hepatitis B Virus X RNA by Catalytic Hammerhead Ribozymes or DNA-Enzymes with Antisense DNA-Oligonucleotides or 10-23 DNA-Enzymes that Powerfully Augment In Vitro Sequence-Specific Cleavage Activities. The Open Biotechnology Journal, 2008 2, 1-12.

 

  • Hoshang Unwalla, Samitabh Chakraborti, Sood V, Nidhi Gupta and Akhil C. Banerjea. Potent inhibition of HIV-1 gene expression and TAT mediated apoptosis in human T cells by novel mono- & multitarget anti-TAT/Rev/Env ribozymes and a general purpose RNA-cleaving DNA-enzyme. Antiviral Research 2006 72(2):134-44. PMID: 16790281

 

Participating as Co-PI in DBT finded research project ”Transcriptome analysis for identification of novel biomarker for disease progression in Dengue patients” from 2014-2017.

  • Awarded International Scholarship by International AIDS Society (IAS) to attend 4th International AIDS Conference in Sydney, Australia from 22-25 July, 2007.
  • Awarded Global Health Travel Award by Bill and Melinda Gates Foundation to attend Keystone Symposia on HIV-1 Pathogenesis to be held in New Mexico, USA from 12th to 17th January, 2010.
  • Awarded Global Health Travel Award by Bill and Melinda Gates Foundation to attend Keystone Symposia on HIV-1 Evolution, Pathogenesis and Genomics held in Whistler, Canada from 20th to 25th March, 2011.