People : Scientific : Faculty & Scientists

DR. SHILPA JAMWAL, Ph.D 

Scientist C
+91-129-2876487  (+91-129-2876315)
shilpajamwal [at] thsti [dot] res [dot] in
Ph.D in Biotechnology (2013), Jaipur National University, Jaipur
MSc in Biotechnology (2004), Guru Nanak Dev University
BSc in Biotechnology (2002), Bangalore University (Oxford College of Science)

Research Interests:

My broad objective is to understand the tissue level perturbations in metabolic syndrome leading to metabolism associated complications. Specifically, interest lies in deciphering the early events that trigger and disrupt metabolic homeostasis. These early initiated and erroneous events result in multitude of pathological outcomes like obesity, Diabetes type 2, Cardiovascular disease and so on. To complement my quest, my interests also involve development and optimizations for robust and sensitive assays for High Content and High throughput screening platforms. The knowledge of early events will be employed in screening natural compounds as potential therapeutics.

Quantitative Proteomics and Lipidomics Analysis of Endoplasmic Reticulum of Macrophage Infected with Mycobacterium tuberculosis.

Saquib NM, Jamwal S, Midha MK, Verma HN, Manivel V.

Int J Proteomics. 2015;2015:270438. doi: 10.1155/2015/270438. Epub 2015 Feb 16.

PMID: 25785198

Pathogenicity of Mycobacterium tuberculosis is expressed by regulating metabolic thresholds of the host macrophage.

Mehrotra P, Jamwal SV, Saquib N, Sinha N, Siddiqui Z, Manivel V, Chatterjee S, Rao KV.

PLoS Pathog. 2014 Jul 24;10(7):e1004265. doi: 10.1371/journal.ppat.1004265. eCollection 2014 Jul.

PMID: 25058590

Characterizing virulence-specific perturbations in the mitochondrial function of macrophages infected with Mycobacterium tuberculosis.

Jamwal S, Midha MK, Verma HN, Basu A, Rao KV, Manivel V.

Sci Rep. 2013;3:1328. doi: 10.1038/srep01328.

PMID: 23435464

Mycobacterium tuberculosis-driven targeted recalibration of macrophage lipid homeostasis promotes the foamy phenotype.

Singh V, Jamwal S, Jain R, Verma P, Gokhale R, Rao KV.

Cell Host Microbe. 2012 Nov 15;12(5):669-81. doi: 10.1016/j.chom.2012.09.012.

PMID: 23159056

Mycobacterial escape from macrophage phagosomes to the cytoplasm represents an alternate adaptation mechanism.

Jamwal SV, Mehrotra P, Singh A, Siddiqui Z, Basu A, Rao KV.

Sci Rep. 2016 Mar 16;6:23089. doi: 10.1038/srep23089.

PMID: 26980157

Quantitative Proteomics and Lipidomics Analysis of Endoplasmic Reticulum of Macrophage Infected with Mycobacterium tuberculosis.

Saquib NM, Jamwal S, Midha MK, Verma HN, Manivel V.

Int J Proteomics. 2015;2015:270438. doi: 10.1155/2015/270438. Epub 2015 Feb 16.

PMID: 25785198

Pathogenicity of Mycobacterium tuberculosis is expressed by regulating metabolic thresholds of the host macrophage.

Mehrotra P, Jamwal SV, Saquib N, Sinha N, Siddiqui Z, Manivel V, Chatterjee S, Rao KV.

PLoS Pathog. 2014 Jul 24;10(7):e1004265. doi: 10.1371/journal.ppat.1004265. eCollection 2014 Jul.

PMID: 25058590

Characterizing virulence-specific perturbations in the mitochondrial function of macrophages infected with Mycobacterium tuberculosis.

Jamwal S, Midha MK, Verma HN, Basu A, Rao KV, Manivel V.

Sci Rep. 2013;3:1328. doi: 10.1038/srep01328.

PMID: 23435464

Mycobacterium tuberculosis-driven targeted recalibration of macrophage lipid homeostasis promotes the foamy phenotype.

Singh V, Jamwal S, Jain R, Verma P, Gokhale R, Rao KV.

Cell Host Microbe. 2012 Nov 15;12(5):669-81. doi: 10.1016/j.chom.2012.09.012.

PMID: 23159056