People : Scientific : Faculty & Scientists

DR. JAYANTA BHATTACHARYA, PhD., MNASc. 

Principal Investigator
+91-129-2867307  (+91-129-6525508)
jbhattacharya [at] thsti [dot] res [dot] in
Ph.D. (Physiology), University of Calcutta (1999)
PRINCIPAL SCIENTIST-II, INTERNATIONAL AIDS VACCINE INITIATIVE
Deputy Director & Head, Dept. of Molecular Virology, National AIDS Research Institute, ICMR, Pune (2010-2012)
Visiting Scientist, Duke University School of Medicine, Durham, NC, USA (2006)
Instructor, Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA, USA (2004-2005)
Postdoctoral Associate, Meharry Medical College, Nashville, Tennessee, USA (1999-2001)

Principal Scientist-II, International AIDS Vaccine Initiative

Positions held

1993-1998: Junior and Senior Research Fellowat the National Institute of Cholera and Enteric Diseases, ICMR, P33 CIT Road, Scheme-XM, Beliaghata, Calcutta 700010, INDIA.Field of Study: Pathophysiology of Enteric bacteria.

1999 -2001: Postdoctoral Research Associate, Department of Microbiology, Meharry Medical College, Nashville, TN 37208, USA.Field of Study: Template interaction in Alphavirus replication.

2002-2003: Senior Postdoctoral Research Associatein the Department of Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA. Field of Study: HIV Pathogenesis.

2004-2005: Instructor(Non-tenured track faculty) in the Department of Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605,  USA. Field of Study: HIV Pathogenesis.

2006-2010: Assistant Director and Head, Division of Molecular Virology at the National AIDS Research Institute, Indian Council of Medical Research, Pune,  India.

2010-2012: Deputy Director and Head, Division of Molecular Virology at the National AIDS Research Institute, Indian Council of Medical Research, Pune India.

2013-2014: Principal Scientist & Principal Investigator, International AIDS Vaccine Initiative, THSTI-IAVI HIV Vaccine Design Program, Translational Health and Technology Institute (THSTI), Gurgaon, Haryana

2014-Present:  Principal Scientist-II & Principal Investigator, International AIDS Vaccine Initiative, THSTI-IAVI HIV Vaccine Design Program, Translational Health  and Technology Institute (THSTI), NCR Biotech Science Cluster, Faridabad, Haryana

1)     Kumar, R., Ozorowski, G., Kumar, V., Holden, L., Shrivastava, T., Patil, S., Deshpande, S., Ward, A.B., Bhattacharya, J*. (2017). Characterization of a stable HIV-1 B/C recombinant, soluble and trimeric envelope glycoprotein (Env) highly resistant to CD4-induced conformational changes. Journal of Biological Chemistry. Jul 25. pii: jbc.M117.803056. doi: 10.1074/jbc.M117.803056

2)     Qureshi, H. and Bhattacharya, J.* (2017). Dual immunity concomitantly suppress HIV-1 progression. Trends in Microbiol. 25 (5): 334-335.

3)     Khan, L., Kumar, R., Thiruvengadam, R., Parray, H.A., Makhdoomi, M.A., Kumar, S., Aggarwal, H., Mohata, M., Hussain, A.W., Das, R., Varadarajan, R., Bhattacharya, J., Vajpayee, M., Murugavel, K.G., Solomon, S., Sinha, S., Luthra, K.* (2017). Cross-neutralizing anti-HIV-1 human single chain variable fragments (scFvs) against CD4 binding site and N332 glycan identified from a recombinant phage library. Scientific Reports. Mar 23; 7: 45163.

4)     Deshpande, S., Patil, S., Kumar, R., Shrivastava, T., Srikrishnan, A.K., Murugavel, K.G., Koff, W.C., Chakrabarti, B.K., Bhattacharya, J*. (2016). Association of mutations in V3/C3 domain with enhanced sensitivity of HIV-1 clade C primary envelopes to autologous broadly neutralizing plasma antibodies. Retrovirology 13: 41

5)     Despande, S., Patil, S., Kumar, R., Hermanus, T., Murugavel, K.G., Solomon, S., Morris, L., Bhattacharya, J*.(2016) HIV-1 clade C escapes broadly neutralizing autologous antibodies with N332 glycan specificity by distinct mechanisms. Retrovirology30;13(1):60

6)     Patil, S., Kumar, R., Deshpande, S., Samal, S., Shrivastava, T., Boliar, S., Bansal, M., Chaudhary, N.K., Srikrishnan, A.K., Murugavel, K.G., Solomon, S., Simek, M., Koff, W.C., Goyal, R., Chakrabarti, B.K., Bhattacharya, J.*(2016). Conformational Epitope-Specific Broadly Neutralizing Plasma Antibodies Obtained from an HIV-1 Clade C Infected Elite Neutralizer Mediate Autologous Virus Escape through Novel Mutations in V1 Loop. Journal of Virology 90 (7):3446-3457.

7)     Khan, L., Makhdoomi, M.A., Kumar S., Nair, A., Andrabi, R., Clark, B.E.,  Auyeung, K., Bhattacharya, J., Vajpayee, M., Wig, N., Pantophlet, R., Luthra, K. (2015). Identification of CD4-binding site dependent plasma neutralizing antibodies in an HIV-1 infected Indian individual PLoS One 10(5):e0125575

8)     Boliar S, Das, S., Bansal, M., Shukla, B.N., Patil, S., Shrivastava, T., Samal, S., Goswami, S., King, C.R., Bhattacharya, J., Bimal K Chakrabarti (2015). An efficiently cleaved HIV-1 clade C Env selectively binds to neutralizing antibodies. PLoS One 10(3): e0122443

9)     SV Kulkarni, M Bala, J Bhattacharya, A Risbud. (2015). Detection of mutations in mtrR gene in quinolone resistant strains of N.gonorrhoeae isolated from India. Indian Journal of Medical Microbiology, 33(2): 277-281

10)  Patil, S., Choudhary, I., Chaudhary, N., Ringe, R, Bansal, M, Shukla, B.N., Boliar, S., Chakrabarti, B.K., and Bhattacharya, J.* (2014). Determinants in V2C2 region of HIV-1 clade C primary envelopes conferred altered neutralization susceptibilities to IgG1b12 and PG9 monoclonal antibodies in context dependent manner. Virology 462-463: 266–272

11)  Tilghman MW , Bhattacharya J., Deshpande S, Ghate M, Espitia S, Grant I, Marcotte TD, Smith D, Mehendale S. (2014). Genetic attributes of blood-derived subtype-C HIV-1 tat and env in India and neurocognitive function. J Med Virol. 86(1): 88-96

12)  Mahajan S.D, Gaekwad A, Pawar J, Tripathy S, Ghate M, Bhattacharya J, Singh HO, Schwartz SA, Paranjape R, Gangakhedkar R. (2014). Cardiac Morbidity in an HIV-1 Lipodystrophy Patient Cohort Expressing the TNF-α-238 G/A Single Nucleotide Gene Polymorphism. Curr HIV Res. 13: 98-108

13)  Ringe, R. and Bhattacharya, J.*(2013). Preventive and therapeutic applications of neutralizing antibodies to Human Immunodeficiency Virus Type 1. Therapeutic Adv in Vaccines. 1: 67-80

14)  Gautam, A. and Bhattacharya, J.*(2013). Evidence that Vpu Modulates HIV-1 Gag-Envelope Interaction towards Envelope Incorporation and Infectivity in a Cell Type Dependent Manner. PLoS One 8(4): e61388

15)  Ghate M, Tripathy S, Gangakhedkar R, Thakar M, Bhattacharya J, Choudhury I, Risbud A, Bembalkar S, Kadam D, Rewari BB, Paranjape R. (2013). Use of first line antiretroviral therapy from a free ART programme clinic in Pune, India - A preliminary report. Indian J Medical Research 137(5):942-9

16)  Choudhary, I., Chimanpure, V., Patil, A., and Bhattacharya, J.* (2013).Single step detection of HIV-1 proviral DNA and housekeeping β-actin gene from dried blood spots by monoplex polymerase chain reaction. J Virol Methods 187: 203-206.

17)  Kulkarni S, Bala M, Sane S, Pandey S, Bhattacharya J, Risbud A. (2012). Mutations in the gyrA and parC genes of quinolone-resistant Neisseria gonorrhoeae isolates in India. Int J Antimicrob Agents. 40(6):549-53

18)  Patil, A. and Bhattacharya, J.* (2012). Natural deletion of L35Y36 in p6 gag eliminate LYPXnL/ALIX auxiliary virus release pathway in HIV-1 subtype C. Virus Research 170: 154-158

19)  Gautam, A.*, Patil, A. and Bhattacharya, J. (2012). Gag-Vpu cross talk modulating HIV-1 envelope incorporation and infectivity in cell-type dependent manner. BMC Infectious Diseases 12 (Suppl 1): P49          

20)  Ringe, R., Das, L., Choudhury, I., Sharma, D., Paranjape, R., Chauhan, V.S., and Bhattacharya, J.* (2012). Unique sequence pattern in the C2V3 region in HIV-1 envelope obtained from broadly neutralizing plasma of an antiretroviral naïve chronically infected patient conferred enhanced neutralization by exposition of discontinuous neutralizing epitopes. PLoS One7(10):e46713.

21)  Ringe, R., and Bhattacharya, J.* (2012).Association of enhanced HIV-1 neutralization by a single residue substitution in gp41 with increased gp120-CD4 interaction and macrophage infectivity. PLoS One 7(5): e37157

22)  Ringe, R., Phogat, S. and Bhattacharya, J*. (2012). Subtle alteration of residues including N-linked glycans in V2 loop modulates HIV-1 neutralization by PG9 and PG16 monoclonal antibodies. Virology 426: 34–41

23)  Gharu, L., Ringe, R., and Bhattacharya, J.* (2012). Evidence of extended alternate coreceptor usage by HIV-1 clade C envelope obtained from an Indian patient. Virus Research 163 (2012) 410–414

24)  Ringe, R., Sharma, D., Zolla-Pazner, S., Phogat, S., Risbud, A., Thakar, M., Paranjape, R and Bhattacharya, J.* (2011)A single amino acid substitution in the C4 region in gp120 confers enhanced neutralization of HIV-1 by modulating CD4 binding sites and V3 loop, Virology 418: 123–132

25)  Gharu, L., Ringe, R., and Bhattacharya, J*. (2011). HIV-1 clade C envelopes obtained from late stage symptomatic Indian patients varied in their ability towards relative CD4 usages and sensitivity to CCR5 antagonist TAK-779. Virus Research 158: 216–224

26)  Mukhopadhyay, S., Ringe, R., Patil, A., Paranjape, R and Bhattacharya, J*. (2011) Characterization of circulating HIV-1 env genes in plasma of two antiretroviral naïve slow progressing patients with broad neutralizing antibody response with evidence of recombination. AIDS Res Human Retroviruses28(7):739-45.

27)  Jadhav, S., Tripathy, S., Kulkarni, S., Chaturbhuj, D., Ghare, R., Bhattacharya, J.* and Paranjape, R. (2011) Genetic conservation in gp36 transmembrane sequences of Indian HIV-2 isolates (2011). AIDS Res Human Retroviruses (May 19. [Epub ahead of print] PMID: 21453135)

28)  Gharu, L., Ringe, R., Anupindi S., Patil, A and Bhattacharya, J.* (2011). Evidence of HIV-1 clade C env clones containing low V3 loop charge obtained from an AIDS patient in India that uses CXCR6 and CCR8 for entry in addition to CCR5. AIDS Res Human Retroviruses 27 (2): 211-219

29)   Ringe, R., Thakar, M. and Bhattacharya, J.* (2010). Variations in autologous neutralization and CD4 dependence of b12 resistant HIV-1 clade 1 C env clones obtained at different time points from antiretroviral naïve Indian patients with recent infection. Retrovirology 7:76

30)  Sharma, D. and Bhattacharya, J.* (2010) Evolutionary constraints acting on DDX3X protein potentially interferes with Rev-mediated nuclear export of HIV-1 RNA. PLoS One 5(3): e9613.

31)  Patil, A., Gautam, A and Bhattacharya, J.* (2010) Evidence that Gag facilitates HIV-1 envelope association both in GPI-enriched plasma membrane and detergent resistant membranes and facilitates envelope incorporation onto virions in primary CD4+ T cells. Virology J7: 3

32)  Sharma, D. and Bhattacharya, J.* (2009). Dynamics of evolution of HIV-1 Rev binding host factors with their predicted role in HIV associated neuropathogenesis. Journal of Neurovirology, 15 (Supplementary 1): 88-89 (DOI: 10.1080/13550280903016074)

33)  Gharu, L., Ringe, R., Pandey, S., Paranjape, S., and Bhattacharya, J.* (2009). HIV-1 clade C env clones obtained from an Indian patient exhibiting expanded coreceptor tropism are presented with naturally occurring unusual amino acid substitutions in V3 loop. Virus Research 144:306-314.

34)   Sharma, D and Bhattacharya, J.* (2009). Cellular and Molecular Basis of HIV-Associated Neuropathogenesis. Indian Journal of Medical Research 129: 637-651

35)  Ringe, R., Gharu, R., Satyakumar, A., Pandey, S., Thakar, M. and Bhattacharya, J *. (2008). Genetic and Neutralization Properties of HIV-1 India Clade C Envelope in Recent Infection: Correlation with CCR5 Usage and Clonal Divergence. AIDS Res Human Retrovirus 24 Supplement 1: 33-33. (DOI: 10.1089/aid.2008.9997a).

36)  The Six Week Extended Dose Nevirapine (SWEN) Study Team (2008). Extended Dose of Nevirapine to Six Weeks of Age for Infants in Ethiopia, India and Uganda: A Randomized Trial for Prevention of HIV Transmission through Breastfeeding. Lancet 372: 300-313

37)  Lakhashe, S., Tripathy, S.P., Paranjape, R.S. and Bhattacharya, J.* (2008). Evidence of a Novel B/C Recombinant Exhibiting Unique Breakpoints of Nearly Full Length HIV-1 Genome in North Eastern India. AIDS Res Human Retroviruses 24 (2): 229-234

38)  Lakhashe, S., Tripathy, S.P., Paranjape, R.S. and Bhattacharya, J.* (2008). Characterization of B/C Recombinants of Nearly Full Length HIV-1 in North Eastern India with Mosaics Identical to ARE195FL but with a Different Ancestral Origin. AIDS Res Human Retroviruses 24 (1): 92-99

39)  Peters P.J., Sullivan, W.M, Duenas Decamp, M., Bhattacharya, J., Ankghuambom, C., Brown, R., Luzuriaga, K., Bell, J., Simmonds, P., Ball, J and Clapham, P.R. (2006). Macrophage-tropic R5 envelopes are infrequent in blood, lymph nodes and semen: Implications for transmission and pathogenesis. Journal of Virology 80: 6324-6332

40)  Bhattacharya, J., Repik, A. and Clapham, P.R. (2006). Gag regulates Human Immunodeficiency virus type 1 envelope association with detergent resistant membranes. Journal of Virology 80: 5292-5300

41)  Bhattacharya, J., Peters, P.J., and Clapham, P.R. (2004). Human Immunodeficiency virus type 1 envelope glycoproteins that lack cytoplasmic domain cysteines: Impact on association with membrane lipid rafts and incorporation onto budding virus particles. Journal of Virology, 8: 5500-5506.

42)  Bhattacharya, J.,* Peters, P.J.,* Hibbitts, S.,* Dittmar, M.T., Simmons, G.S, Bell, J., Simmonds, P.S. and Clapham, P.R. (2004). Biological analysis of HIV-R5 envelopes amplified from brain and lymph node tissue of AIDS patients with neuropathology reveals two distinct tropism phenotypes and identifies envelopes in brain that confer an enhanced tropism and fusigenicity for macrophages. Journal of Virology 78: 6915-6926 [* equal contribution].

43)  Bhattacharya, J., Peters, P. J., and Clapham, P.R. (2003). CD4-independent infection of HIV and SIV: implications for envelope conformation and cell tropism in vivo. AIDS: S35-S43.

44)  Bhattacharya, J., Samanta, S., Hoque, K.M., Mukherjee, A. and Chakrabarti, M.K. (2001). Escherichia coli heat stable enterotoxin receptors and guanylyl cyclase activity in the intestinal brush border membrane of hamsters and guinea pigs. Indian Journal of Medical Research, 113; 5-10

45)  Bhattacharya, J. and Chakrabarti, M.K. (1999). Binding of Escherichia coli heat stable toxin and rise of guanylyl cyclase activity in the brush border membranes of rabbit intestinal epithelial cells. Journal of Diarrhoeal Diseases Research; 1; 28-33.

46)  Basu, I., Mitra, R., Saha, P.K., Ghosh, A.N., Bhattacharya, J., Chakrabarti, M.K., Takeda, Y. and Nair G.B. (1999). Morphological and cytoskeletal changes caused by non-membrane damaging cytotoxin of Vibrio cholerae on INT 407 and HeLa cells. FEMS Microbiology Letters. 179(2): 255-63.

47)  Bhattacharya, J. and Chakrabarti, M.K. (1998). Rise of intracellular free calcium levels with activation of inositol triphosphate in a human colonic carcinoma cell line (COLO 205) by heat-stable enterotoxin of Escherichia coli. Biochimica et Biophysica Acta.1403 (1): 1-4.

48)  Bhattacharya, J., Chaudhuri AG, Sinha AK, Samanta AK, Chakrabarti MK. (1997) Binding of Escherichia coli heat-stable enterotoxin and rise of cyclic GMP in COLO 205 human colonic carcinoma cells. FEMS Microbiology Letters; 156 (1): 79-83.

49)  Chakrabarti, M.K., Bhattacharya, J., Bhattacharya, M.K., Nair, G.B., Bhattacharya, S.K., Mahalanabis. D. (1999). Killed oral Shigella vaccine made from Shigella flexneri 2a protects against challenge in the rabbit model of shigellosis. Acta Paediatr. 88 (2): 161-5.

50)  Chaudhuri, A.G., Bhattacharya, J., Nair, G.B., Takeda, T. and Chakrabarti, M.K. (1998). Rise of cytosolic Ca2+ and activation of membrane-bound guanylyl cyclase activity in rat enterocytes by heat-stable enterotoxin of Vibrio cholerae non-01. FEMS Microbiology Letters. 1998 160(1): 125-9.

51)  Chakrabarti, M.K., Bhattacharya, M.K, Bhattacharya, J., Bhattacharya, S.K., and Mahalanabis, D. (1998). Evaluation of different antibiotics in inhibiting colonization of Vibrio cholerae O1 and O139 in the rabbit intestine. Chemotherapy. 44(2): 108-11.

52)  Chakrabarti, M. K., Bhattacharya, J., Sinha, A.K., De, S.P. (1995). Role of outer membrane proteins on the adherence of Vibrio parahaemolyticus to rabbit intestinal epithelial cell in vitro. International Journal of Medical Microbiology. 282(4): 436-41.

53)  Chakrabarti, M.K., Bhattacharya, J. and De, S.P. (1995). Hemagglutinating activities of different strains of Vibrio parahaemolyticus. Medical Science Research 23: 497-498.

54)  Chakrabarti, M.K. and Bhattacharya, J. (1996). Cyclic 3’ 5’ adenosine monophosphate in bacteria. Indian Journal of Physiology and Allied Science, 50: 128-135.

1.     Ambrose CS, Bhattacharya J, Fox CB, McIntosh ED, Stern PL. Therapeutic Advances in Vaccines. 2013 SAGE Publication, London, UK. May; 1(1):3-5. doi: 10.1177/2051013613486264.

2.     Bhattacharya, Jayanta. Unconventional technologies accelerating HIV Vaccine Discovery. Spinco Biotech CuttingEdge Newsletter. September 2015: page 22-24

1.    PUBLISHED

       U.S. Patent Application Jointly Filed by the International AIDS Vaccine Initiative and Translational Health Sciences & Technology Institute (62/068,202);

      CLEAVED FUNCTIONAL HIV-1 CLADE C ENVELOPE GLYCOPROTEIN.

      Filed October 25, 2014

      Saikat Boliar, Supratik Das, Jayanta Bhattacharya, Bimal K. Chakrabarti (PI)

 

2.    Provisional U.S. Patent Application Filed by the International AIDS Vaccine Initiative (62/189,418); HIV-1 CLADE C ENVELOPE GLYCOPROTEINS

        Filed July 07, 2015

       Jayanta Bhattacharya (PI), Suprit Deshpande, Shilpa Patil, Rajesh Kumar, Bimal K. Chakrabarti

 

3.    Provisional Indian Patent Application Filed by the Translational Health Science & Technology Institute, Dept of Biotechnology (# 201611004727)

       ISOLATED NUCLEOTIDE SEQUENCE USEFUL FOR THE PREVENTION OF HIV-1 INFECTION

                      Filed February 10, 2016

                     Jayanta Bhattacharya (PI), Suprit Deshpande, Shilpa Patil, Rajesh Kumar, K.G. Murugavel

 

4.    Provisional U.S. Patent Application Filed by the International AIDS Vaccine Initiative (62334636); Engineered Recombinant Protein Antigen of Trimeric              Mimic of HIV-1 Envelope Glycoprotein Spike

      Filed May 11, 2016

     Jayanta Bhattacharya (PI), Rajesh Kumar, Vivek Kumar Yadav, Shilpa Patil

1.     Department of Biotechnology, Ministry of Science & Technology, Govt of India. “Characterization of HIV-1 primary envelopes obtained from broadly cross neutralizing plasma for their degree of cleavage, sensitivity to neutralizing and non-neutralizing antibodies and immunogenicity”National Bioscience Award Project Status: Active. Role: Principal Investigator. Period: 2014-2017

 

2.     Department of Biotechnology, Ministry of Science & Technology, Govt of India. “Construction and Characterization of Genetically Engineered Chimeric HIV-1 Envelope Protein Modulating Virus Neutralization: Implication and Relevance in Vaccine development”Status: Completed. Role: Principal Investigator. Awarded amount: INR 53.87 Lacs. Period: 2010-2013

 

3.     Department of Science and Technology (Ministry of Science & Technology, Govt of India). “Identification of neutralizing antibody epitopes on Indian and South African HIV-1 subtype C viruses for HIV vaccine design”.Status: Completed

Role: Principal Investigator; Awardedamount: INR 136 Lacs. Period: 2011-2015, Type: Multi-centric collaborative project between Indian institutes (NARI, AIIMS, ICGEB, YRGCare) and South Africa (NICD, Johannesburg).

 

4.     NIH Fogarty funded Vanderbilt NARI-NIE-Informatics Training Program (VNNIT) [1D43TW008440-01]. [Multi centric partnership between Vanderbilt University and two leading research institutions in India, the National AIDS Research Institute (NARI) in Pune and the National Institute of Epidemiology (NIE) in Chennai. NARI and NIE are nodal institutes of the Indian Council of Medical Research (ICMR) the Indian counterpart to the National Institutes of Health (NIH), providing national level leadership in the field of biomedical and behavioral research in HIV/AIDS and other infectious diseases, clinical and field epidemiology, and program monitoring and evaluation in India.    

Funded amount: US $ 1.1 million. Period: Completed(2011-2016)

Role: Co-Principal Investigator (PI: Dr Cindy Gadd, Vanderbilt University)

 

5.     Department of Biotechnology (Ministry of Science & Technology, Govt of India) &Indian Council of Medical Research (Ministry of Health & Family Welfare)[2006-2010]

Neutralization Epitope Mapping in HIV-1 Envelope of Indian Origin and Construction of Envelope- Based Peptide Immunogen for Generation of Broadly Cross-Reactive Neutralizing Antibodies.

      Role: Principal Investigator Status: Completed. Awarded amount: INR 54 Lakhs

 

6.     Department of Biotechnology (Ministry of Science & Technology, Govt of India)& Indian Council of Medical Research ((Ministry of Health & Family Welfare)[2006-2010]

Comprehensive molecular analysis of HIV incidence, genetic diversity and anti-retroviral drug-resistance mutations in diverse risk groups across wide geographic locales of India

        Role: Principal Investigator Status: Completed Awarded amount: INR 75 Lakhs

 

7.     Department of Biotechnology (Ministry of Science & Technology, Govt of India)/Indian Council of Medical Research ((Ministry of Health & Family Welfare) [2006-2010]

Establishment of virtual knowledge and resource center for reagents, protocols and technology in context with research in HIV and AIDS.

Role: Principal Investigator & Project Coordinator; Status: Completed Awarded amount: INR 9.92 Lakhs

 

8.     Collaboration of Vaccine Development-Vaccine Immune Monitoring Consortium (CAVD/VIMC): Funded by Bill and Melinda Gates Foundation [2006-2010]

Role: Co-investigator, India site (PI: David Montefiori, Duke University) Status:Completed

 

9.     American Foundation of AIDS Research (amfAR) Fellowship, New York, USA [2004-2006]

Role: Principal Investigator Status: Completed; Awarded amount: US$ 99,000

  • ‘On the Spot Award of Excellence’, by the International AIDS Vaccine Initiative, New York, USA, February, 2015
  • Member, National Academy of Science (MNASc.), India (Allahabad), 2014.
  • National Bioscience Award for Career Development, 2013, Ministry of Science and Technology, Govt of India.
  • Member, DBT Infectious Disease Task Force, 2011-2013
  • Member, Advisory Board, Premier Medical Corporation, 2015, Gujarat
  • Chairperson, IMAPAC 5th Annual Vaccine World India Summit, Pune, March 2015
  • International Travel Award/Fellowship: International AIDS Vaccine Conference, Cape Town, South Africa, 2008.
  • Research Grant Award from The American Foundation for AIDS Research (amfAR), USA, 2005-2006 (at National AIDS Research Institute, Pune, India).
  • Research Fellowship Grant Award from The American Foundation for AIDS Research (amfAR), USA, 2004-2005 (at UMASS Medical School, Worcester, USA).
  • UNESCO-ASM Visiting Resource Person Program Award, 2005.
  • Travel Grant Award 11th Conference on Retrovirus & Opportunistic infection, San Francisco, CA, USA 2004.
  • Travel Grant Award 12th Conference on Retrovirus & Opportunistic infection, Boston, MA, USA, 2005
  • Prof. P.B.Sen Memorial award from The Physiological Society of India (1998).
  • Senior and Junior Research Fellowships from Indian Council of Medical Research (1993-1998).
  • Prof Arun Sen Award for ranking FIRST in B.Sc. (Honors), Burdwan University, 1989. 

 

Principal Scientist-II, International AIDS Vaccine Initiative

Positions held

1993-1998:       Junior and Senior Research Fellowat the National Institute of Cholera and Enteric Diseases, ICMR, P33 CIT Road, Scheme-XM, Beliaghata, Calcutta                              700010, INDIA.Field of Study: Pathophysiology of Enteric bacteria.

1999 -2001:       Postdoctoral Research Associate, Department of Microbiology, Meharry Medical College, Nashville, TN 37208, USA.Field of Study: Template                                         interaction in Alphavirus replication.

2002-2003:       Senior Postdoctoral Research Associatein the Department of Molecular Medicine, University of Massachusetts Medical School, Worcester, MA                                      01605, USA. Field of Study: HIV Pathogenesis.

2004-2005:        Instructor(Non-tenured track faculty) in the Department of Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605,                                   USA. Field of Study: HIV Pathogenesis.

2006-2010:        Assistant Director and Head, Division of Molecular Virology at the National AIDS Research Institute, Indian Council of Medical Research, Pune,                                   India.

2010-2012:        Deputy Director and Head, Division of Molecular Virology at the National AIDS Research Institute, Indian Council of Medical Research, Pune,                                         India.

2013-2014:        Principal Scientist & Principal Investigator, International AIDS Vaccine Initiative, THSTI-IAVI HIV Vaccine Design Program, Translational Health and                               Technology Institute (THSTI), Gurgaon, Haryana

 

2014-Present:  Principal Scientist-II & Principal Investigator, International AIDS Vaccine Initiative, THSTI-IAVI HIV Vaccine Design Program, Translational Health                                    and Technology Institute (THSTI), NCR Biotech Science Cluster, Faridabad, Haryana

 

Member of Professional Bodies

  1. Member, National Academy of Sciences, Allahabad, India
  2. Past Member, Task Force (Infectious Disease Biology Study Section), Department of Biotechnology, Govt of India
  3. Member, Scientific Advisory Board, Premier Medical Corporation Ltd., Nani Daman, Gujarat.
  4. Member, American Society of Microbiology
  5. Life member, Physiological Society of India

 

Editorial Board Member

  1. Associate Editor & Senior Editorial Management Team, Therapeutic Advances in Vaccines, SAGE Publications Ltd, London, UK.
  2. Member, Editorial Board of World Journal of Virology, Baishideng Publishing Group.
  3. Section Editor & Senior Editorial Board Member, VirusDisease, Springer Publications Inc.

DR. TRIPTI SHRIVASTAVA
SCIENTIST

DR. SWEETY SAMAL
SCIENTIST

DR. SUPRATIK DAS
SENIOR SCIENTIST

MR. MANISH BANSAL
LAB TECHNICIAN

MR. NARESH KUMAR
LAB TECHNICIAN

DR. RAJESH KUMAR
SCIENTIST

DR. HUMA QURESHI
SENIOR SCIENTIST

MR. VIVEK KUMAR
LAB TECHNICIAN

DR. SHUBBIR AHMED
SENIOR SCIENTIST

DR. SUPRIT DESHPANDE
SCIENTIST

MR. ANKUSH KUMAR RANA
LAB TECHNICIAN

 

Ph.D. Students (Awarded) under my direct supervision:

Name

UNIVERSITY

Current Status

Dr. Lavina Gharu

PUNE UNIVERSITY (2011)

POST-DOC (ICGEB, TRIESTE, ITALY)

Dr. Rajesh Ringe

PUNE UNIVERSITY (2012)

POST-DOC (CORNELL UNIV, NY, USA)

Dr. Archana Gautam

PUNE UNIVERSITY (2012)

POST-DOC (CORNELL UNIV, NY, USA)

Dr. Deepak Sharma

PUNE UNIVERSITY (2012)

POST-DOC (CASE WESTERN, CLEVELAND, USA)

Dr. Sampurna Mukhopadhyay

PUNE UNIVERSITY (2013)

POST-DOC (POPULATION COUNCIL, NEW YORK, USA)

 

Postdoctoral & Postgraduate Associates

1. Dr. Suprit Deshpande (Ph.D., Gulbarga University) (2013-2016) (Current status: Scientist at the HVTR Laboratory, THSTI)

2. Dr. Lipsa Das (M.Tech, IIT Kharagpur): 2010-2011 (Current status: PhD student, University of Arizona, USA)

 

M.Sc., M.Tech, B. Tech Students (selected students carried out their dissertation studies under my direct supersion):

1. Dr. Alok Joglekar, (M. Tech, Pune University) - Current status (Ph.D at UCLA, USA and currently at CalTech in Prof David Baltimore's Laboratory)

2. Yogaditya Chakraborty, (M. Tech, Pune University): Current status - at IICB Kolkata pusuing PhD.

3. Debanjan Mukherjee (B.Sc. St Xavier’s College, Kolkata): Following his training he moved to TIFR, Mumbai (currently pursuing PhD, Harvard School of Public Health, Boston)

4. Dr Adonia Kim: Currently Scientist at BioHelix Corporation, Boston, MA, USA.

5. Dr. Shravan Kumar Mishra (M.Sc. Virology Pune University): Currently Health Researcher, Ministry of Health and Population, Nepal

6. Deepti Patki: Currently Clinical Research Coordinator, University of Mississippi Medical Center, USA.

7. Sandeep Sadashiv Patil (M.Sc. Virology Pune University): Currently at the University of Wuerzburg, Germany pursuing PhD.

8. Archana Seetharaman (Stella Maris College, Chennai): Currently at the The Institute of Mathematical Sciences, Chennai.

9. Soumya Kusumaskshi (Kannur University, Kerala): Currently pursuing Ph.D. at the University of Saarland School of Medicine, Saarbrücken Area, Germany