The HIV Vaccine Translational Research Laboratory is a joint initiative established in 2012 between the Department of Biotechnology (DBT), Translational Health Science and Technology Institute (THSTI) and the International AIDS Vaccine Initiative (IAVI). The HIV Vaccine Translational Research (HVTR) Laboratory is a research facility at the THSTI NCR Biotech Science Cluster in Faridabad, Haryana, India working to design and evaluate preventive HIV vaccines, particularly ones that elicit an immune response capable of neutralizing a broad spectrum of HIV variants with HIV immunogens—the active ingredients of vaccines.
HIV's extensive genetic variability & mutability, and the multiple mechanisms that it has developed to avoid detection and elimination by the body's immune response, has challenged and evaded effective targeting by past strategies for vaccine development. The HVTR Lab's research for broadly neutralising antibodies, we believe, will prove to be the novel paradigm that would facilitate and accelerate next-generation vaccine development for HIV.
About IAVI The International AIDS Vaccine Initiative (IAVI) is a global not-for-profit organization whose mission is to ensure the development of safe, effective, accessible, preventive HIV vaccines for use throughout the world. Founded in 1996, IAVI works with partners in 25 countries to research, design and develop AIDS vaccine candidates. The organization also conducts policy analysis and serves as an advocate for the AIDS vaccine field. It supports a comprehensive approach to addressing HIV and AIDS that balances the expansion and strengthening of existing HIV prevention and treatment programs with targeted investments in the design and development of new tools to prevent HIV. IAVI is dedicated to ensuring that a future AIDS vaccine will be available and accessible to all who need it. IAVI's work is made possible by generous support from many donors including: the Bill & Melinda Gates Foundation; the Ministry of Foreign Affairs of Denmark; Irish Aid; the Ministry of Finance of Japan in partnership with The World Bank; the Ministry of Foreign Affairs of the Netherlands; the Norwegian Agency for Development Cooperation (NORAD); the United Kingdom Department for International Development (DFID), and the United States Agency for International Development (USAID). The full list of IAVI donors is available at www.iavi.org.Learn more>>
The Department of Biotechnology (DBT), Ministry of Science and Technology was set up in 1986 to give a new impetus to the development of the field of modern biology and biotechnology in India. Through several R&D projects, demonstrations, technology transfers and creation of infrastructural facilities, DBT has become a major national R&D agency. It has also nurtured human resource development and ensured a networking for knowledge sharing and dissemination. The Department has made significant contributions in the field of agriculture, health care, animal sciences, environment and industry.
Focused on the wider mandate of Biotechnology in India, the department serves as a nodal point for international collaborations, evolving regulatory guidelines, information dissemination and identifying and setting up Centres of Excellence for R&D in India. Learn more>>